HESI A2
Biology HESI A2 Practice Test
1. Which of the following is an example of human error in an experiment?
- A. an imperfectly calibrated scale
- B. contaminating a sterile sample by breathing on it
- C. a draft in the laboratory slightly changing the temperature of a liquid
- D. failure to account for wind speed when measuring distance traveled
Correct answer: B
Rationale: Contaminating a sterile sample by breathing on it is an example of human error in an experiment because it involves an action directly caused by the researcher that compromises the integrity of the sample. Breathing on a sterile sample introduces external contaminants that can affect the results. Choices A, C, and D involve factors not directly under the researcher's control or are technical errors that do not involve direct human actions.
2. Which component of the cell contributes to the protection, communication, and passage of substances into and out of the cell?
- A. Nucleus
- B. Cell membrane
- C. Endoplasmic reticulum
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the cell membrane. The cell membrane is responsible for protecting the cell, facilitating communication with the external environment, and regulating the passage of substances into and out of the cell. The nucleus (Choice A) is the control center of the cell and houses the genetic material but is not primarily involved in these functions. The endoplasmic reticulum (Choice C) is involved in protein synthesis and lipid metabolism, not primarily in protection or communication. The cytoplasm (Choice D) is the gel-like substance that fills the cell but does not specifically contribute to protection, communication, or substance passage.
3. What helps the cell maintain its shape and allows it to adapt?
- A. Microfilaments
- B. Cytoplasm
- C. Cytoskeleton
- D. Centrioles
Correct answer: C
Rationale: The cytoskeleton is the correct answer. It provides structural support to the cell, helps maintain its shape, and enables it to adapt to different environments. Microfilaments are part of the cytoskeleton, but they alone do not encompass the entire cytoskeleton's functions. Cytoplasm is the fluid inside the cell where organelles are suspended and is not directly responsible for maintaining cell shape. Centrioles are involved in cell division and do not primarily contribute to maintaining the cell's shape and adaptation.
4. Which of the following is not a product of the Krebs cycle?
- A. carbon dioxide
- B. oxygen
- C. adenosine triphosphate (ATP)
- D. energy carriers
Correct answer: B
Rationale: The correct answer is B: oxygen. Oxygen is not a product of the Krebs cycle. During the Krebs cycle, carbon dioxide, adenosine triphosphate (ATP), and energy carriers like NADH and FADH2 are produced. Carbon dioxide is a byproduct of the cycle, ATP is a form of energy produced, and energy carriers play a crucial role in transferring energy within the cell. Therefore, oxygen is the only option that is not a product of the Krebs cycle, making it the correct answer.
5. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
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