HESI A2
Biology HESI A2 Practice Test
1. Which of the following is an example of human error in an experiment?
- A. an imperfectly calibrated scale
- B. contaminating a sterile sample by breathing on it
- C. a draft in the laboratory slightly changing the temperature of a liquid
- D. failure to account for wind speed when measuring distance traveled
Correct answer: B
Rationale: Contaminating a sterile sample by breathing on it is an example of human error in an experiment because it involves an action directly caused by the researcher that compromises the integrity of the sample. Breathing on a sterile sample introduces external contaminants that can affect the results. Choices A, C, and D involve factors not directly under the researcher's control or are technical errors that do not involve direct human actions.
2. DNA bases include all but which of the following?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is not a DNA base; it is a base found only in RNA. The four bases in DNA are Adenine, Thymine, Cytosine, and Guanine. Choice A, Adenine, is a correct DNA base. Choice B, Thymine, is a correct DNA base. Choice D, Cytosine, is a correct DNA base. Therefore, Uracil is the only incorrect choice among the options provided.
3. Which of the following is not found within a bacterial cell?
- A. mitochondria
- B. DNA
- C. vesicles
- D. ribosome
Correct answer: A
Rationale: The correct answer is A: mitochondria. Mitochondria are not found in bacterial cells. Bacterial cells lack membrane-bound organelles like mitochondria, which are commonly found in eukaryotic cells. Choices B, C, and D are all components that can be found within a bacterial cell. Bacterial cells contain DNA as their genetic material, vesicles for various cellular functions, and ribosomes for protein synthesis. Therefore, the presence of mitochondria is the distinguishing factor that is not found in bacterial cells, making option A the correct answer.
4. Which of the following structures is not directly involved in translation?
- A. tRNA
- B. mRNA
- C. ribosome
- D. DNA
Correct answer: D
Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.
5. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
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