HESI A2
Biology HESI A2 Practice Exam
1. Which cellular structure is largely protective in function?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: C
Rationale: The correct answer is C: Cell membrane. The cell membrane, also known as the plasma membrane, is largely protective in function as it serves as a selectively permeable barrier that surrounds the cell, providing structural support and helping to maintain cell integrity. It regulates the movement of substances in and out of the cell, thus protecting the cell from harmful external factors while allowing essential nutrients to enter. Mitochondrion (choice A) is responsible for energy production, not primarily protective. Vacuole (choice B) is mainly involved in storage and transport. Ribosome (choice D) is involved in protein synthesis, not protective functions.
2. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
3. The two catabolic pathways that lead to cellular energy production are:
- A. fermentation and protein synthesis
- B. cellular respiration and glycolysis
- C. fermentation and glycolysis
- D. cellular respiration and fermentation
Correct answer: D
Rationale: The correct answer is D: cellular respiration and fermentation. Cellular respiration involves the breakdown of glucose in the presence of oxygen to produce ATP, which is the primary source of energy for cells. Fermentation, on the other hand, occurs in the absence of oxygen and produces ATP through glycolysis followed by specific fermentation pathways. Choices A, B, and C are incorrect. Protein synthesis is a biosynthetic process, not a catabolic pathway for energy production. Glycolysis is a common step in both cellular respiration and fermentation, so it is not a pair of distinct catabolic pathways. Therefore, the most accurate pairing of catabolic pathways for cellular energy production is cellular respiration and fermentation.
4. What is the term for the movement of ions and other molecular substances across cell membranes without the need for energy?
- A. Active Transport
- B. Passive Transport
- C. Diffusion
- D. Osmosis
Correct answer: B
Rationale: Passive transport refers to the movement of substances across cell membranes without the need for energy input. In contrast, active transport, choice A, requires energy to move substances against their concentration gradient. Diffusion, choice C, is a type of passive transport where substances move from an area of high concentration to low concentration. Osmosis, choice D, specifically refers to the movement of water molecules across a selectively permeable membrane.
5. What molecule is primarily responsible for providing energy to the cell?
- A. ATP
- B. DNA
- C. ADP
- D. Glycogen
Correct answer: A
Rationale: Correct! ATP (Adenosine Triphosphate) is the main molecule that stores and provides energy for cellular activities. ATP is known as the energy currency of the cell, where energy released from the breakdown of nutrients is stored in the high-energy phosphate bonds of ATP. Choices B, C, and D are incorrect because DNA carries genetic information, ADP is the precursor of ATP, and glycogen is a polysaccharide used for energy storage, not direct energy provision.
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