HESI A2
Biology HESI A2 Practice Test
1. Which is true of gametes?
- A. They are diploid cells
- B. They are haploid cells
- C. They are somatic
- D. A & C are true
Correct answer: B
Rationale: Gametes are sex cells (sperm and eggs) that are involved in sexual reproduction. They are haploid cells, meaning they have half the number of chromosomes (n) compared to diploid cells. This is necessary for the formation of a diploid zygote when two gametes unite during fertilization. Somatic cells are non-reproductive cells in the body, so they are not gametes. Choice A is incorrect because gametes are not diploid but haploid. Choice C is incorrect because gametes are not somatic cells.
2. What happens during the S phase of the cell cycle?
- A. Chromosomes are duplicated.
- B. Cell growth occurs.
- C. DNA is synthesized.
- D. DNA is destroyed.
Correct answer: A
Rationale: During the S phase of the cell cycle, chromosomes are duplicated. This is a critical step in cell division as each chromosome is replicated to ensure that the resulting daughter cells receive an identical set of genetic information. Choices B, C, and D are incorrect because cell growth primarily occurs in the G1 phase, DNA synthesis happens during the S phase, and DNA destruction does not occur during any phase of the cell cycle.
3. In which phase of mitosis do new nuclear membranes form around sets of chromosomes?
- A. Prophase
- B. Anaphase
- C. Telophase
- D. Interphase
Correct answer: C
Rationale: The correct answer is C, Telophase. During telophase, the final phase of mitosis, new nuclear membranes form around sets of chromosomes at the opposite poles of the cell. This process marks the completion of nuclear division in mitosis. Choices A, B, and D are incorrect because in prophase, chromosomes condense but nuclear membranes are not formed; in anaphase, chromosomes separate and move to opposite poles but no new nuclear membranes are formed; and in interphase, the cell prepares for division but nuclear membranes are not forming around sets of chromosomes.
4. Which cellular structure is largely protective in function?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: C
Rationale: The correct answer is C: Cell membrane. The cell membrane, also known as the plasma membrane, is largely protective in function as it serves as a selectively permeable barrier that surrounds the cell, providing structural support and helping to maintain cell integrity. It regulates the movement of substances in and out of the cell, thus protecting the cell from harmful external factors while allowing essential nutrients to enter. Mitochondrion (choice A) is responsible for energy production, not primarily protective. Vacuole (choice B) is mainly involved in storage and transport. Ribosome (choice D) is involved in protein synthesis, not protective functions.
5. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
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