HESI A2
HESI A2 Biology 2024
1. Which is not a product of the Krebs cycle?
- A. ATP
- B. Carbon dioxide
- C. Glucose
- D. NADH
Correct answer: C
Rationale: Glucose is not a direct product of the Krebs cycle. Glucose is a starting molecule that undergoes glycolysis outside the mitochondria to produce pyruvate, which then enters the mitochondrial matrix to participate in the Krebs cycle. The Krebs cycle primarily generates ATP, carbon dioxide, and NADH as products. Choices A, B, and D are all products of the Krebs cycle, making them incorrect answers.
2. Which of the following animals would have the least energy efficiency in nutrient consumption?
- A. Cow
- B. Caterpillar
- C. Coyote
- D. Cricket
Correct answer: A
Rationale: Cows are ruminant animals that have multiple stomachs and require large amounts of food to digest and convert into energy. They have lower energy efficiency compared to insects like caterpillars, coyotes, and crickets, which have more efficient nutrient consumption processes. The digestive system and metabolic functions of cows result in them having the least energy efficiency in nutrient consumption among the given choices. Caterpillars, coyotes, and crickets have more efficient nutrient consumption processes, making them more energy-efficient than cows.
3. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
4. How many phases are there in the process of mitosis?
- A. 2
- B. 3
- C. 4
- D. 5
Correct answer: C
Rationale: The correct answer is C: '4'. Mitosis consists of four phases: prophase, metaphase, anaphase, and telophase. These phases are crucial in the orderly division of the cell's genetic material. Choice A is incorrect because mitosis is a more complex process involving multiple phases. Choice B is incorrect as it is one phase short of the total phases in mitosis. Choice D is incorrect as mitosis does not consist of five phases.
5. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
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