HESI A2
HESI A2 Biology 2024
1. Which is not a product of the Krebs cycle?
- A. ATP
- B. Carbon dioxide
- C. Glucose
- D. NADH
Correct answer: C
Rationale: Glucose is not a direct product of the Krebs cycle. Glucose is a starting molecule that undergoes glycolysis outside the mitochondria to produce pyruvate, which then enters the mitochondrial matrix to participate in the Krebs cycle. The Krebs cycle primarily generates ATP, carbon dioxide, and NADH as products. Choices A, B, and D are all products of the Krebs cycle, making them incorrect answers.
2. Within the biological hierarchical system of organization, which of the following is least inclusive?
- A. phylum
- B. order
- C. kingdom
- D. species
Correct answer: D
Rationale: The correct answer is 'D: species.' In the biological hierarchical system of organization, a species is the least inclusive level. A species consists of organisms that share similar characteristics and can interbreed to produce fertile offspring. On the other hand, a phylum, order, and kingdom are more inclusive classifications that encompass multiple species. Phylum groups together related classes, order groups together related families, and kingdom groups together related phyla. Therefore, species is the least inclusive category within the biological hierarchical system.
3. During which phase is the chromosome number reduced from diploid to haploid?
- A. S phase
- B. interphase
- C. mitosis
- D. meiosis I
Correct answer: D
Rationale: The correct answer is 'meiosis I.' During meiosis I, the chromosome number is reduced from diploid to haploid through two rounds of division. Choice A ('S phase') is incorrect as the S phase is part of the cell cycle where DNA is replicated. Choice B ('interphase') is also incorrect as interphase is the phase where the cell prepares for division. Choice C ('mitosis') is incorrect as mitosis is a process where a diploid cell divides to produce two identical diploid daughter cells, maintaining the chromosome number.
4. The force per unit area exerted against a surface by the weight of air above that surface in the Earth's atmosphere is the ______.
- A. Atmospheric pressure
- B. Barometric density
- C. Aneroid pressure
- D. Barometric pressure
Correct answer: A
Rationale: Atmospheric pressure is the correct term for the force per unit area exerted against a surface by the weight of air above that surface in the Earth's atmosphere. It is commonly measured in units such as pascals, millibars, or inches of mercury. Barometric density and aneroid pressure are not accurate descriptions for this phenomenon. Barometric density refers to the density of the atmosphere at a particular location, while aneroid pressure is linked to a type of barometer but not a comprehensive term for the force exerted by the weight of air.
5. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
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