HESI A2
HESI A2 Biology 2024
1. Which is not a product of the Krebs cycle?
- A. ATP
- B. Carbon dioxide
- C. Glucose
- D. NADH
Correct answer: C
Rationale: Glucose is not a direct product of the Krebs cycle. Glucose is a starting molecule that undergoes glycolysis outside the mitochondria to produce pyruvate, which then enters the mitochondrial matrix to participate in the Krebs cycle. The Krebs cycle primarily generates ATP, carbon dioxide, and NADH as products. Choices A, B, and D are all products of the Krebs cycle, making them incorrect answers.
2. What is the main function of the cell membrane?
- A. Energy production
- B. Communication
- C. Protein synthesis
- D. Waste removal
Correct answer: B
Rationale: The main function of the cell membrane is communication. It acts as a barrier that regulates the passage of substances in and out of the cell, maintaining cellular homeostasis. Choices A, C, and D are incorrect because energy production occurs in the mitochondria, protein synthesis takes place in the ribosomes, and waste removal is primarily handled by the lysosomes and other organelles within the cell.
3. How many chromosomes do sperm and egg produce in meiosis?
- A. 46
- B. 23
- C. 45
- D. 24
Correct answer: B
Rationale: Sperm and egg cells undergo meiosis to form gametes with half the number of chromosomes found in somatic cells. Each sperm and egg cell produces 23 chromosomes through meiosis. Choice A is incorrect because 46 chromosomes represent the diploid number found in somatic cells. Choice C is incorrect as it is an uncommon number for chromosome production in human gametes. Choice D is incorrect as the total number of chromosomes in sperm or egg cells is 23, not 24.
4. What is the term for the breakdown of glycogen into glucose subunits?
- A. Hydrolysis
- B. Reduction
- C. Metabolism
- D. Transpiration
Correct answer: A
Rationale: Hydrolysis is the term used to describe the breakdown of large molecules into smaller units by adding water. In the case of glycogen being broken down into glucose subunits, this process involves the addition of water molecules to break the glycosidic bonds between glucose molecules, resulting in the release of individual glucose subunits. This process is crucial for providing cells with a source of energy when needed. Choice B, Reduction, refers to a chemical reaction involving a gain of electrons or a decrease in oxidation state, not the breakdown of glycogen into glucose subunits. Choice C, Metabolism, is a broad term encompassing all biochemical processes in an organism, including anabolism and catabolism, but does not specifically describe the breakdown of glycogen into glucose subunits. Choice D, Transpiration, is the process of water movement through a plant and is not related to the breakdown of glycogen into glucose subunits.
5. Which two bases are purines?
- A. Adenine (A)
- B. Cytosine (C)
- C. Thymine (T)
- D. Guanine (G)
Correct answer: A
Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.
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