HESI A2
Biology HESI A2 Practice Exam
1. Which form of fermentation is used to produce beer?
- A. Lactic acid fermentation
- B. Acetic acid fermentation
- C. Propionic acid fermentation
- D. Ethyl alcohol fermentation
Correct answer: D
Rationale: The correct answer is D, Ethyl alcohol fermentation. During beer production, yeast metabolizes sugars in the wort to produce ethanol (ethyl alcohol) and carbon dioxide, which are responsible for the alcohol content and carbonation in beer. Choices A, B, and C are incorrect because lactic acid fermentation produces lactic acid, acetic acid fermentation produces acetic acid, and propionic acid fermentation produces propionic acid, none of which are used in the production of beer.
2. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
3. What are the two catabolic pathways that lead to cellular energy production?
- A. Fermentation and internal respiration
- B. Fermentation and external respiration
- C. Fermentation and cellular respiration
- D. Fermentation and anaerobic respiration
Correct answer: C
Rationale: The correct answer is 'Fermentation and cellular respiration.' Fermentation is an anaerobic catabolic process that occurs in the absence of oxygen, producing limited amounts of ATP. Cellular respiration, on the other hand, is the aerobic catabolic pathway that occurs in the presence of oxygen and is the most efficient way of producing ATP. Choices A, B, and D are incorrect because internal respiration, external respiration, and anaerobic respiration are not the correct pathways leading to cellular energy production.
4. Genes control heredity in man and other organisms. This gene is ___
- A. A segment of DNA
- B. A bead-like structure on the chromosomes
- C. A protein molecule
- D. A segment of RNA
Correct answer: A
Rationale: Genes are sections of DNA that contain instructions for building and operating living organisms. These sections of DNA contain the genetic information that is passed on from one generation to the next. Genes are composed of specific sequences of nucleotides within the DNA molecule. Therefore, genes are best described as segments of DNA. Choice A is correct. Choice B is incorrect because genes are not bead-like structures on chromosomes but specific sequences of DNA. Choice C is incorrect because genes are not protein molecules but rather sequences of nucleotides. Choice D is incorrect because genes are not segments of RNA but DNA.
5. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
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