HESI A2
HESI A2 Biology 2024
1. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
2. The cell membrane consists of a bilayer of phospholipids with proteins, cholesterol, and glycoproteins. What does this bilayer create?
- A. Impermeable
- B. Permeable
- C. Selectively permeable
- D. Selectively impermeable
Correct answer: C
Rationale: The correct answer is 'Selectively permeable.' The cell membrane's bilayer structure allows it to be selectively permeable, meaning it can control the passage of substances. This property enables the membrane to regulate the entry and exit of specific molecules, ions, and other substances. Choice A, 'Impermeable,' is incorrect as the cell membrane is not completely impermeable and does allow certain substances to pass through. Choice B, 'Permeable,' is also incorrect as it does not address the selective nature of the membrane. Choice D, 'Selectively impermeable,' is a contradictory term and does not accurately describe the cell membrane's function.
3. The sum of all chemical reactions that occur in an organism is:
- A. product
- B. respiration
- C. metabolism
- D. synthesis
Correct answer: C
Rationale: Metabolism is the sum of all chemical reactions that occur within an organism to maintain life. It involves all the processes that break down molecules to release energy (catabolism) and build new molecules to support growth and maintenance (anabolism). Respiration refers specifically to the process of generating energy from the breakdown of glucose molecules. Synthesis is the creation of complex molecules from simpler ones. Therefore, metabolism is the most comprehensive term that encompasses all these processes within an organism.
4. Which structure controls the passage of substances into and out of the cell?
- A. Vacuole
- B. Cell Membrane
- C. Nuclear Membrane
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the Cell Membrane. The cell membrane acts as a barrier that controls the passage of substances into and out of the cell. It is selectively permeable, allowing only certain molecules to pass through. Vacuole (Choice A), Nuclear Membrane (Choice C), and Cytoplasm (Choice D) do not primarily regulate the passage of substances in and out of the cell. Vacuoles are responsible for storage, the nuclear membrane surrounds the nucleus providing protection, and the cytoplasm is the fluid where organelles are suspended.
5. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
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