HESI A2
HESI A2 Biology 2024
1. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
2. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
3. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
4. Where can epithelial tissue be found?
- A. Organ lining
- B. Heart muscle
- C. Tendons
- D. Spinal cord
Correct answer: A
Rationale: Epithelial tissue is primarily found lining the surfaces of organs, such as the skin and the linings of various internal organs like the digestive tract, respiratory tract, and blood vessels. It serves as a protective barrier and helps with absorption and secretion. Heart muscle is made up of cardiac muscle tissue, tendons are primarily composed of dense connective tissue, and the spinal cord is composed of nervous tissue, none of which are classified as epithelial tissue.
5. Which of the following animals would have the least energy efficiency in nutrient consumption?
- A. Cow
- B. Caterpillar
- C. Coyote
- D. Cricket
Correct answer: A
Rationale: Cows are ruminant animals that have multiple stomachs and require large amounts of food to digest and convert into energy. They have lower energy efficiency compared to insects like caterpillars, coyotes, and crickets, which have more efficient nutrient consumption processes. The digestive system and metabolic functions of cows result in them having the least energy efficiency in nutrient consumption among the given choices. Caterpillars, coyotes, and crickets have more efficient nutrient consumption processes, making them more energy-efficient than cows.
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