HESI A2
HESI A2 Biology 2024
1. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
2. Select the strand of DNA that would match this segment: ACTTGCA
- A. TGAACGT
- B. GACCATG
- C. ACTTGCA
- D. None of the above
Correct answer: A
Rationale: The correct match for the DNA segment ACTTGCA is TGAACGT. In DNA, adenine (A) always pairs with thymine (T), and cytosine (C) always pairs with guanine (G). Therefore, the complementary strand to ACTTGCA should be TGAACGT, making choice A the correct answer. Choice B (GACCATG) does not follow the base pairing rules; hence, it is incorrect. Choice C (ACTTGCA) is the original segment, not its complementary strand. Choice D is incorrect as well because a matching strand does exist.
3. What cycle is the sequence of reactions by which most living cells generate energy during aerobic respiration?
- A. Calvin Cycle
- B. Krebs Cycle
- C. Photosynthesis
- D. Fermentation
Correct answer: B
Rationale: The Krebs Cycle is the correct answer. It is a series of reactions occurring in the mitochondria and is a crucial part of aerobic respiration. The Calvin Cycle is a part of photosynthesis, not respiration, making choice A incorrect. Photosynthesis (choice C) is the process by which plants, algae, and some bacteria convert light energy into chemical energy. Fermentation (choice D) is an anaerobic process that does not require oxygen and is not the primary energy-generating pathway during aerobic respiration, so it is incorrect.
4. Which of the following cell types has no nucleus?
- A. platelet
- B. red blood cell
- C. white blood cell
- D. phagocyte
Correct answer: B
Rationale: The correct answer is B, red blood cell. In humans, red blood cells do not have a nucleus. This unique feature allows them to have more space to carry oxygen efficiently. Platelets (choice A), white blood cells (choice C), and phagocytes (choice D) all have nuclei. Platelets are cell fragments, while white blood cells and phagocytes are types of immune cells that contain a nucleus for DNA and cellular functions.
5. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
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