HESI A2
HESI A2 Biology 2024
1. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
2. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
3. What is the role of ribosomes in the cell?
- A. Break down cellular waste
- B. Organize cellular division
- C. Synthesize proteins
- D. Provide cellular structure
Correct answer: C
Rationale: The correct answer is C: Synthesize proteins. Ribosomes are responsible for protein synthesis by linking amino acids together. Choice A is incorrect because ribosomes do not break down cellular waste. Choice B is incorrect as ribosomes do not organize cellular division. Choice D is incorrect because ribosomes do not provide cellular structure.
4. If bacteria are placed in a strong solution of salt water, they will shrink as water moves out of the bacteria. What is this process called?
- A. Dehydration synthesis
- B. Hydrolysis
- C. Osmosis
- D. Isotonic transport
Correct answer: C
Rationale: Osmosis is the process by which water molecules move across a semipermeable membrane from an area of lower solute concentration to an area of higher solute concentration. In this case, when bacteria are placed in a strong solution of salt water, the high concentration of solutes outside the bacteria causes water to move out of the bacteria, leading to shrinkage. This process is known as osmosis. Dehydration synthesis (Choice A) is a process where molecules combine by removing water. Hydrolysis (Choice B) is the breakdown of molecules by the addition of water. Isotonic transport (Choice D) does not accurately describe the specific movement of water in or out of bacterial cells in a hypertonic solution.
5. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
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