HESI A2
HESI A2 Biology 2024
1. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
2. Which organelle is found in protists but not in monerans?
- A. Golgi apparatus
- B. Chromosome
- C. Cytoplasm
- D. Cell membrane
Correct answer: A
Rationale: The Golgi apparatus is the correct answer. The Golgi apparatus is a cellular organelle responsible for processing and packaging proteins before they are transported to their final destination. Protists, being eukaryotic organisms, have membrane-bound organelles including the Golgi apparatus, which are absent in monerans. Monerans are prokaryotic organisms that lack membrane-bound structures such as the Golgi apparatus. Choices B, C, and D are incorrect as chromosomes, cytoplasm, and cell membranes are present in both protists and monerans.
3. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
4. Physical factors such as temperature and pH can alter enzyme activity because they have an effect on the enzyme's ___________.
- A. acidity
- B. shape
- C. chemistry
- D. substrate
Correct answer: B
Rationale: Physical factors such as temperature and pH can alter enzyme activity by affecting the enzyme's shape. Enzymes rely on their specific shapes to function properly and catalyze reactions. Any changes in temperature or pH can disrupt these shapes, causing the enzyme to become denatured and lose its functionality. Therefore, alterations in temperature and pH can impact enzyme activity by directly affecting their shapes. Choices A, C, and D are incorrect because while pH can affect acidity and chemical properties of the enzyme, and temperature can influence the enzyme-substrate interaction, the primary reason for enzyme activity alteration due to temperature and pH is the change in the enzyme's shape.
5. Which organelle provides storage space for the cell?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: B
Rationale: The correct answer is B: Vacuole. The vacuole is the organelle responsible for providing storage space in the cell. It stores water, nutrients, waste products, and other essential materials required by the cell. Vacuoles are crucial for maintaining cell structure and regulating cellular processes. Mitochondrion (choice A) is known as the powerhouse of the cell, responsible for producing energy. The cell membrane (choice C) is a protective barrier around the cell, regulating what enters and exits the cell. Ribosomes (choice D) are involved in protein synthesis, not storage.
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