HESI A2
HESI A2 Biology 2024
1. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
2. During protein synthesis, what process creates a complementary strand of RNA from a DNA template?
- A. Transcription
- B. Translation
- C. Transformation
- D. Replication
Correct answer: A
Rationale: The correct answer is 'Transcription.' During protein synthesis, transcription is the process that creates a complementary RNA strand from a DNA template. This process involves the synthesis of mRNA using DNA as a template. Choice B, 'Translation,' is incorrect as it is the process where the genetic code carried by mRNA is decoded to produce a specific polypeptide chain. Choice C, 'Transformation,' is not related to the synthesis of RNA from a DNA template. Choice D, 'Replication,' is the process of copying DNA to produce an identical DNA molecule, not RNA.
3. DNA bases include all but which of the following?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is not a DNA base; it is a base found only in RNA. The four bases in DNA are Adenine, Thymine, Cytosine, and Guanine. Choice A, Adenine, is a correct DNA base. Choice B, Thymine, is a correct DNA base. Choice D, Cytosine, is a correct DNA base. Therefore, Uracil is the only incorrect choice among the options provided.
4. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
5. How does an enzyme work on a chemical reaction that occurs in a substrate?
- A. An enzyme slows down the chemical reaction.
- B. An enzyme speeds up the chemical reaction.
- C. An enzyme has no effect on the chemical reaction.
- D. An enzyme stops most chemical reactions.
Correct answer: B
Rationale: Enzymes are biological catalysts that facilitate chemical reactions by lowering the activation energy required for the reaction to occur. This allows the reaction to proceed more quickly and efficiently. Enzymes do not change the overall outcome of the reaction, but they significantly increase the rate at which it takes place. Therefore, choice B, 'An enzyme speeds up the chemical reaction,' is the correct answer. Choices A, C, and D are incorrect because enzymes do not slow down, have no effect, or stop chemical reactions; instead, they accelerate the process by lowering the activation energy.
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