Nursing Elites

1. What property of a substance remains constant regardless of the amount of the substance present?

• A. Mass
• B. Weight
• C. Density
• D. Volume

Correct answer: C

Rationale: The correct answer is C, Density. Density is a physical property of a substance that remains constant regardless of the amount of the substance present. Mass (Choice A) is the amount of matter in an object and can change depending on the amount of the substance. Weight (Choice B) is the force exerted on an object due to gravity and can vary with location. Volume (Choice D) is the amount of space occupied by a substance and can change if the amount of the substance changes.

2. What is the term for a genetic disorder caused by a mutation on the X chromosome?

• A. Autosomal dominant disorder
• B. Autosomal recessive disorder
• C. Sex-linked recessive disorder
• D. Sex-linked dominant disorder

Correct answer: C

Rationale: A genetic disorder caused by a mutation on the X chromosome is termed a sex-linked recessive disorder (Option C). This type of disorder is more commonly seen in males due to their single X chromosome, making them more vulnerable to X-linked mutations. Females have two X chromosomes, providing a protective effect against X-linked disorders.\n- Autosomal dominant disorders (Option A) result from a mutation in one copy of a gene on non-sex chromosomes (autosomes) and are not specifically related to the X chromosome.\n- Autosomal recessive disorders (Option B) occur due to mutations in both copies of a gene on autosomes, not on the X chromosome.\n- Sex-linked dominant disorders (Option D) are rare and lead to more severe symptoms in males as they only require one copy of the mutated gene on the X chromosome to express the disorder. However, this is not the term for a genetic disorder caused by an X chromosome mutation.

3. What cells compose the epidermis?

• A. Keratinocytes
• B. Epithelial cells
• C. Fibroblasts
• D. Melanocytes

Correct answer: A

Rationale: The correct answer is A - Keratinocytes. The epidermis is primarily composed of keratinocytes, which are a type of epithelial cell. Keratinocytes synthesize the protein keratin, providing protection against physical damage and water loss. While epithelial cells are correct, specifying keratinocytes is more precise. Fibroblasts are not the main cell type in the epidermis; they are found in the dermis, where they produce collagen and other extracellular matrix components. Melanocytes are responsible for producing melanin pigment in the skin and are also present in the epidermis, but they are not the predominant cell type like keratinocytes.

4. What ethical considerations are associated with the potential use of CRISPR-Cas9 technology in humans?

• A. Concerns about unintended consequences on the genome and potential off-target effects.
• B. Debates on modifying the human germline and potential eugenic implications.
• C. Accessibility and affordability of the technology, ensuring equitable access to benefits.
• D. Risks associated with CRISPR-Cas9 editing germline cells and potential long-term impacts.

Correct answer: B

Rationale: The correct answer is B. CRISPR-Cas9 technology allows precise editing of germline cells, raising ethical concerns about modifying the human gene pool. This includes potential eugenic implications, debates on altering future generations, and the moral implications of such genetic modifications. Choice A discusses unintended consequences and off-target effects, but the primary ethical consideration with CRISPR-Cas9 technology relates to altering the human germline. Choices C and D, while important factors, are not the central ethical dilemmas associated with using CRISPR-Cas9 technology in humans.

5. Which of the following is the cardiac muscle layer that forms the bulk of the heart?

• A. Endocardium
• B. Epicardium
• C. Fibrous skeleton
• D. Myocardium

Correct answer: D

Rationale: The correct answer is D, Myocardium. The myocardium is the cardiac muscle layer that comprises the majority of the heart's muscle mass. It is responsible for the heart's contractions, allowing it to pump blood throughout the body. The endocardium is the innermost layer of the heart lining the chambers, while the epicardium is the outermost layer covering the heart. The fibrous skeleton provides structural support and serves as an attachment point for cardiac muscle fibers. Therefore, choices A, B, and C are incorrect as they do not represent the primary muscle layer of the heart.

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