Nursing Elites

1. What is the term for a genetic disorder caused by a mutation on the X chromosome?

• A. Autosomal dominant disorder
• B. Autosomal recessive disorder
• C. Sex-linked recessive disorder
• D. Sex-linked dominant disorder

Correct answer: C

Rationale: A genetic disorder caused by a mutation on the X chromosome is termed a sex-linked recessive disorder (Option C). This type of disorder is more commonly seen in males due to their single X chromosome, making them more vulnerable to X-linked mutations. Females have two X chromosomes, providing a protective effect against X-linked disorders.\n- Autosomal dominant disorders (Option A) result from a mutation in one copy of a gene on non-sex chromosomes (autosomes) and are not specifically related to the X chromosome.\n- Autosomal recessive disorders (Option B) occur due to mutations in both copies of a gene on autosomes, not on the X chromosome.\n- Sex-linked dominant disorders (Option D) are rare and lead to more severe symptoms in males as they only require one copy of the mutated gene on the X chromosome to express the disorder. However, this is not the term for a genetic disorder caused by an X chromosome mutation.

2. Which of the following produces the first heart sound ('lub')?

• A. The closing of the aortic and pulmonary valves
• B. The closing of the tricuspid and mitral valves
• C. The opening of the aortic and pulmonary valves
• D. The opening of the tricuspid and mitral valves

Correct answer: B

Rationale: The correct answer is B. The first heart sound, known as the 'lub' sound, is produced by the closure of the tricuspid and mitral valves, which are the atrioventricular valves. This sound marks the beginning of systole in the cardiac cycle. Choice A, the closing of the aortic and pulmonary valves, is incorrect as these valves produce the second heart sound ('dub'). Choice C, the opening of the aortic and pulmonary valves, is incorrect because the first heart sound occurs during ventricular contraction (systole). Choice D, the opening of the tricuspid and mitral valves, is incorrect as the 'lub' sound is associated with the closure, not the opening, of these valves.

3. Which term describes the allele for green eyes?

• A. Dominant
• B. Recessive
• C. Homozygous
• D. Heterozygous

Correct answer: B

Rationale: The correct answer is 'B: Recessive.' In genetics, eye color is determined by multiple genes, with green eyes often being associated with a recessive allele. When an individual carries two copies of the recessive allele for green eyes, they will express this eye color. Dominant alleles are expressed over recessive alleles. Homozygous refers to having two identical alleles for a particular gene, and heterozygous refers to having two different alleles. In this context, the allele for green eyes is recessive, meaning it is expressed only when an individual carries two copies of this specific allele. Therefore, 'Recessive' is the most appropriate term to describe the allele for green eyes, making it the correct answer.

4. Which of the following hormones helps regulate blood pressure by affecting kidney function?

• A. Insulin
• B. Testosterone
• C. Renin
• D. Estrogen

Correct answer: C

Rationale: Renin is the hormone that helps regulate blood pressure by affecting kidney function. It is released by the kidneys in response to low blood pressure or low blood volume. Renin plays a crucial role in the renin-angiotensin-aldosterone system, which is responsible for regulating blood pressure and fluid balance in the body. Insulin, testosterone, and estrogen do not directly impact blood pressure regulation through kidney function. Insulin is involved in regulating glucose metabolism, testosterone is a male sex hormone, and estrogen is a female sex hormone. Therefore, the correct answer is Renin (Choice C) because of its specific role in blood pressure regulation through kidney function.

5. The kidneys are bean-shaped organs responsible for filtering waste products from the blood. What is the main nitrogenous waste product the kidneys eliminate?

• A. Carbon dioxide
• B. Ammonia
• C. Urea
• D. Glucose

Correct answer: C

Rationale: The correct answer is C, urea. Urea is the main nitrogenous waste product eliminated by the kidneys. It is produced in the liver from protein metabolism and excreted in urine. Carbon dioxide is eliminated through the lungs as a waste product of cellular respiration and not by the kidneys. Ammonia, a toxic waste product, is converted to urea in the liver before being excreted by the kidneys. Glucose is a sugar that is reabsorbed by the kidneys and not excreted as waste.

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