Nursing Elites

1. What is the role of RNA interference in silencing genes?

• A. Increases protein production
• B. Promotes gene mutation
• C. Inhibits the expression of specific genes
• D. Repairs damaged DNA

Correct answer: C

Rationale: RNA interference (RNAi) is a biological process that involves the silencing of gene expression by inhibiting the translation of mRNA or by degrading mRNA molecules. This mechanism plays a crucial role in regulating gene expression and can be used to selectively silence specific genes. By interfering with the expression of specific genes, RNAi can downregulate protein production from those genes. Therefore, option C, 'Inhibits the expression of specific genes,' is the correct role of RNA interference in silencing genes. Options A, B, and D are incorrect because RNA interference does not increase protein production, promote gene mutation, or repair damaged DNA; its primary function is to inhibit gene expression by degrading or interfering with mRNA.

2. Which of the following water-soluble vitamins is NOT synthesized in the large intestine?

• A. B6
• B. Biotin
• C. Pantothenic acid (Vitamin B5)
• D. Vitamin K

Correct answer: A

Rationale: The correct answer is A: B6. Vitamin B6 is not synthesized in the large intestine, while biotin, pantothenic acid (Vitamin B5), and Vitamin K can be synthesized by gut microflora. Biotin, B5, and K are examples of water-soluble vitamins that can be produced in the large intestine, but B6 needs to be obtained through dietary sources. Therefore, B6 is the correct answer as it is not synthesized within the large intestine, unlike the other options.

3. Which of the following produces the first heart sound ('lub')?

• A. The closing of the aortic and pulmonary valves
• B. The closing of the tricuspid and mitral valves
• C. The opening of the aortic and pulmonary valves
• D. The opening of the tricuspid and mitral valves

Correct answer: B

Rationale: The correct answer is B. The first heart sound, known as the 'lub' sound, is produced by the closure of the tricuspid and mitral valves, which are the atrioventricular valves. This sound marks the beginning of systole in the cardiac cycle. Choice A, the closing of the aortic and pulmonary valves, is incorrect as these valves produce the second heart sound ('dub'). Choice C, the opening of the aortic and pulmonary valves, is incorrect because the first heart sound occurs during ventricular contraction (systole). Choice D, the opening of the tricuspid and mitral valves, is incorrect as the 'lub' sound is associated with the closure, not the opening, of these valves.

4. Which of the following are the blood vessels that transport blood away from the heart?

• A. arteries
• B. capillaries
• C. venules
• D. veins

Correct answer: A

Rationale: Arteries are blood vessels that carry oxygen-rich blood away from the heart to various parts of the body. Therefore, they are the vessels that transport blood away from the heart. Veins, on the other hand, transport blood back to the heart. Capillaries are tiny blood vessels where the exchange of nutrients and waste products occurs between blood and tissues, not vessels that transport blood to the heart. Venules are small veins that collect blood from capillaries and connect them to larger veins, rather than transport blood to the heart.

5. Which of the following layers of skin acts as an energy reserve by storing adipocytes and releasing them into circulation when energy is needed?

• A. epidermis
• B. dermis
• C. hypodermis
• D. stratum basale

Correct answer: C

Rationale: The hypodermis, also known as the subcutaneous tissue, is the deepest layer of the skin. This layer contains adipocytes (fat cells) that act as an energy reserve by storing excess energy in the form of fat. When energy is needed, these stored fats can be released into circulation to be used by the body's cells. The epidermis is the outermost layer of the skin, primarily responsible for providing a protective barrier. The dermis lies between the epidermis and hypodermis and contains blood vessels, nerves, and structures like hair follicles and sweat glands. The stratum basale is the deepest layer of the epidermis, responsible for cell renewal and regeneration.

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