Nursing Elites

1. What is the difference between polygenic inheritance and pleiotropy?

• A. Polygenic inheritance involves multiple genes influencing one trait, while pleiotropy involves one gene affecting multiple traits.
• B. Polygenic inheritance is found in simple Mendelian traits, while pleiotropy is found in complex traits.
• C. Polygenic inheritance is always quantitative, while pleiotropy can be qualitative or quantitative.
• D. Both involve multiple genes and multiple traits, but the specific mechanisms differ

Correct answer: A

Rationale: - Polygenic inheritance refers to the situation where a trait is influenced by multiple genes, each contributing a small effect to the phenotype. These traits often show continuous variation and are not easily categorized into discrete categories. - Pleiotropy, on the other hand, occurs when a single gene influences multiple, seemingly unrelated traits. This means that a mutation in one gene can lead to multiple phenotypic effects across different traits or characteristics. - Therefore, the key difference between polygenic inheritance and pleiotropy lies in the number of genes involved in influencing a trait (multiple genes in polygenic inheritance vs. one gene in pleiotropy) and the direction of influence (one trait affected by multiple genes in polygenic inheritance vs. multiple traits affected by one gene in pleiotropy).

2. Which of the following is a function of the skeletal system?

• A. To produce red blood cells
• B. To provide structural support
• C. To transport nutrients
• D. To store fat

Correct answer: B

Rationale: The correct answer is B: To provide structural support. The skeletal system is primarily responsible for supporting the body's structure, protecting internal organs, facilitating movement, and storing minerals. While bones do play a role in producing red blood cells (hematopoiesis) in the bone marrow, the main function related to the question is providing structural support. Choices C and D are incorrect as the skeletal system is not involved in transporting nutrients or storing fat. The main functions of the skeletal system are related to support, protection, movement facilitation, mineral storage, and hematopoiesis.

3. Elements tend to gain or lose electrons to achieve stable electron configurations like those of noble gases. Their group number often indicates the number of electrons gained/lost and the resulting ionic charge, providing a good starting point for prediction.

• A. Ionic bonds involve electron sharing, while metallic bonds involve electron transfer.
• B. Ionic bonds are weak and directional, while metallic bonds are strong and non-directional.
• C. Ionic bonds exist between metals and non-metals, while metallic bonds exist only between metals.
• D. Ionic bonds form discrete molecules, while metallic bonds form extended structures.

Correct answer: C

Rationale: Ionic bonds typically form between metals and non-metals, where one atom donates electrons (cation) and the other accepts electrons (anion). This results in the transfer of electrons. Metallic bonds, on the other hand, occur between metal atoms where electrons are shared among a sea of delocalized electrons, leading to the characteristic properties of metals like malleability and conductivity. Choice A is incorrect because ionic bonds involve electron transfer, not sharing. Choice B is incorrect as ionic bonds are strong, not weak, and are non-directional, while metallic bonds are strong and non-directional. Choice D is incorrect as ionic bonds do not form discrete molecules but rather a lattice structure, whereas metallic bonds form extended structures.

4. Where is the scaphoid bone located in the body?

• A. Wrist
• B. Shoulder
• C. Spine
• D. Face

Correct answer: A

Rationale: The correct answer is A: Wrist. The scaphoid bone is one of the carpal bones located in the wrist. It is a small boat-shaped bone that is frequently involved in wrist injuries, such as falls onto an outstretched hand resulting in a scaphoid fracture. Choices B, C, and D are incorrect as the scaphoid bone is not located in the shoulder, spine, or face. Understanding the anatomical location of bones is crucial for diagnosing and treating injuries accurately.

5. What is the primary function of the CRISPR-Cas9 system in gene editing?

• A. To amplify specific DNA sequences.
• B. To cut DNA at specific locations.
• C. To deliver genes into cells.
• D. To sequence entire genomes.

Correct answer: B

Rationale: The CRISPR-Cas9 system is a powerful tool used in gene editing to precisely target and cut DNA at specific locations within the genome. This system consists of a guide RNA that directs the Cas9 enzyme to the desired DNA sequence, where it creates a double-strand break. This break can then be repaired by the cell's natural DNA repair mechanisms, allowing for the introduction of specific genetic modifications. Options A, C, and D are incorrect as they do not accurately describe the primary function of the CRISPR-Cas9 system in gene editing. Amplifying DNA sequences, delivering genes into cells, and sequencing entire genomes are not the main functions of the CRISPR-Cas9 system, which is primarily focused on precise DNA cutting for targeted genetic modifications.

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