Nursing Elites

1. What is the difference between polygenic inheritance and pleiotropy?

• A. Polygenic inheritance involves multiple genes influencing one trait, while pleiotropy involves one gene affecting multiple traits.
• B. Polygenic inheritance is found in simple Mendelian traits, while pleiotropy is found in complex traits.
• C. Polygenic inheritance is always quantitative, while pleiotropy can be qualitative or quantitative.
• D. Both involve multiple genes and multiple traits, but the specific mechanisms differ

Correct answer: A

Rationale: - Polygenic inheritance refers to the situation where a trait is influenced by multiple genes, each contributing a small effect to the phenotype. These traits often show continuous variation and are not easily categorized into discrete categories. - Pleiotropy, on the other hand, occurs when a single gene influences multiple, seemingly unrelated traits. This means that a mutation in one gene can lead to multiple phenotypic effects across different traits or characteristics. - Therefore, the key difference between polygenic inheritance and pleiotropy lies in the number of genes involved in influencing a trait (multiple genes in polygenic inheritance vs. one gene in pleiotropy) and the direction of influence (one trait affected by multiple genes in polygenic inheritance vs. multiple traits affected by one gene in pleiotropy).

2. Which blood type is considered a universal donor?

• A. A
• B. B
• C. AB
• D. O

Correct answer: D

Rationale: Blood type O is considered the universal donor because individuals with type O blood can donate red blood cells to individuals with any ABO blood type (A, B, AB, or O) without causing an adverse reaction. Type O blood lacks A or B antigens on the surface of red blood cells, minimizing the risk of an immune response when transfused into individuals with different blood types. Therefore, type O blood is in high demand for blood transfusions in emergency situations when the recipient's blood type is unknown or when there is a shortage of specific blood types. Choices A, B, and AB are not considered universal donors. Individuals with blood types A, B, or AB can only donate to individuals with compatible blood types to avoid adverse reactions since they have A and/or B antigens on the surface of their red blood cells, making them incompatible with all blood types.

3. How can bacteria acquire new genetic material from their environment?

• A. Transformation
• B. Transduction
• C. Conjugation
• D. All of the above

Correct answer: D

Rationale: A) Transformation: Transformation is the process by which bacteria can take up free DNA from their environment and incorporate it into their own genome, leading to the acquisition of new genetic material and traits. B) Transduction: Transduction involves the transfer of genetic material from one bacterium to another by a bacteriophage, a virus that infects bacteria. The bacteriophage carries bacterial DNA from one host cell to another, facilitating the transfer of genetic material. C) Conjugation: Conjugation is a mechanism of horizontal gene transfer in bacteria where genetic material is transferred between two bacterial cells in direct contact. This transfer is facilitated by a conjugative plasmid carrying the genetic information. Therefore, all the processes mentioned (transformation, transduction, and conjugation) are ways in which bacteria can acquire new genetic material from their environment.

4. Which of the following types of stem cells can differentiate into any cell type, including forming an entire organism?

• A. Totipotent stem cells
• B. Multipotent stem cells
• C. Pluripotent stem cells
• D. Hematopoietic stem cells

Correct answer: A

Rationale: Totipotent stem cells possess the unique ability to differentiate into any cell type, including forming an entire organism. These cells have the highest potency level and can give rise to both embryonic and extraembryonic cell types, allowing them to develop into a complete organism. Multipotent stem cells (Choice B) can differentiate into a limited range of cell types within a specific tissue or organ. Pluripotent stem cells (Choice C) can differentiate into any cell type in the body except for those needed to support and develop a fetus. Hematopoietic stem cells (Choice D) are a type of multipotent stem cell that can differentiate into various blood cell types.

5. How many amino acids can make up a protein?

• A. 10-20
• B. 50-100
• C. 100-500
• D. 1000+

Correct answer: A

Rationale: Proteins are made up of long chains of amino acids, and there are 20 standard amino acids commonly found in proteins. The sequence and arrangement of these amino acids determine the structure and function of a protein. While proteins can vary in size and complexity, the number of amino acids typically ranges from around 10 to 20 in smaller proteins to hundreds or even thousands in larger proteins. Therefore, the range of 10-20 amino acids is the most accurate representation of the number of amino acids that can make up a protein. Choices B, C, and D are incorrect as they provide ranges that are beyond the typical number of amino acids found in proteins and may lead to confusion. The correct answer is A (10-20).

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