HESI A2
HESI A2 Biology Practice Test 2024
1. What is DNA made of?
- A. Proteins
- B. Nucleotides
- C. Lipids
- D. Carbohydrates
Correct answer: B
Rationale: DNA is made up of nucleotides, which are the building blocks of genetic material. Choice A (Proteins) is incorrect because while proteins play a crucial role in the body, they are not the building blocks of DNA. Choice C (Lipids) and Choice D (Carbohydrates) are also incorrect as they are not the primary components of DNA.
2. The procedure to focus an image using a compound microscope involves
- A. Adjusting the coarse adjustment each time a new magnification is selected
- B. Adjusting the fine adjustment each time a new magnification is selected
- C. Adjusting the stage each time a new magnification is selected
- D. All of the above
Correct answer: B
Rationale: When using a compound microscope, it is essential to adjust the fine adjustment knob each time you switch to a new magnification level. The fine adjustment knob allows for precise focusing on the specimen at different magnifications, ensuring a clear and sharp image. The coarse adjustment knob is typically used only at the lower magnification settings to bring the image into view roughly. Adjusting the stage may be necessary based on the size and thickness of the specimen, but it does not need to be done every time a new magnification is selected. Therefore, option B is the correct choice as it focuses on the key aspect of precise focusing during magnification changes.
3. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
4. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
5. Which organism reproduces via spore formation?
- A. Shelf fungus
- B. Lemon tree
- C. Smallmouth bass
- D. Staphylococcus
Correct answer: A
Rationale: The correct answer is A, Shelf fungus. Shelf fungus reproduces via spore formation. Spores are tiny, reproductive cells that are released into the environment to be carried by air or water, allowing the fungus to spread and reproduce. The other choices are incorrect because Lemon tree reproduces via seeds, Smallmouth bass reproduce sexually through the fertilization of eggs by sperm, and Staphylococcus bacteria reproduce by binary fission, dividing into two identical daughter cells.
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