HESI A2
Biology HESI A2 Practice Test
1. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
2. Which organelle is the site of energy production?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion. The mitochondrion is the site of energy production in a cell. It is often referred to as the powerhouse of the cell because it is where cellular respiration occurs, generating energy in the form of adenosine triphosphate (ATP) through processes like the citric acid cycle and oxidative phosphorylation. The other organelles listed play different roles in the cell - vacuoles store materials, the cell membrane regulates the movement of substances in and out of the cell, and ribosomes are involved in protein synthesis.
3. The procedure to focus an image using a compound microscope involves
- A. Adjusting the coarse adjustment each time a new magnification is selected
- B. Adjusting the fine adjustment each time a new magnification is selected
- C. Adjusting the stage each time a new magnification is selected
- D. All of the above
Correct answer: B
Rationale: When using a compound microscope, it is essential to adjust the fine adjustment knob each time you switch to a new magnification level. The fine adjustment knob allows for precise focusing on the specimen at different magnifications, ensuring a clear and sharp image. The coarse adjustment knob is typically used only at the lower magnification settings to bring the image into view roughly. Adjusting the stage may be necessary based on the size and thickness of the specimen, but it does not need to be done every time a new magnification is selected. Therefore, option B is the correct choice as it focuses on the key aspect of precise focusing during magnification changes.
4. DNA bases include all but which of the following?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is not a DNA base; it is a base found only in RNA. The four bases in DNA are Adenine, Thymine, Cytosine, and Guanine. Choice A, Adenine, is a correct DNA base. Choice B, Thymine, is a correct DNA base. Choice D, Cytosine, is a correct DNA base. Therefore, Uracil is the only incorrect choice among the options provided.
5. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
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