HESI A2
Biology HESI A2 Practice Test
1. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
2. Which cells in the human body lack nuclei?
- A. Nerve cells
- B. Red blood cells
- C. Liver cells
- D. Connective tissue cells
Correct answer: B
Rationale: Red blood cells, also known as erythrocytes, lack nuclei in humans. This absence of a nucleus allows more space for hemoglobin, the protein responsible for carrying oxygen, making red blood cells efficient at their function of oxygen transport in the body. Nerve cells (Choice A), liver cells (Choice C), and connective tissue cells (Choice D) all possess nuclei as they require genetic material for their functions, such as cell signaling, protein synthesis, and structural support.
3. Which organelle is responsible for organizing protein synthesis?
- A. Nucleus
- B. Ribosome
- C. Lysosome
- D. Vacuole
Correct answer: B
Rationale: The correct answer is B: Ribosome. Ribosomes are responsible for organizing protein synthesis by assembling amino acids. They are the cellular machinery where proteins are synthesized. The other choices, such as the nucleus, lysosome, and vacuole, do not directly participate in protein synthesis. The nucleus contains DNA and controls cell activities, the lysosome is involved in digestion and waste removal, and the vacuole is responsible for storage and maintaining cell turgor pressure.
4. Which organelle is the site of energy production?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion. The mitochondrion is the site of energy production in a cell. It is often referred to as the powerhouse of the cell because it is where cellular respiration occurs, generating energy in the form of adenosine triphosphate (ATP) through processes like the citric acid cycle and oxidative phosphorylation. The other organelles listed play different roles in the cell - vacuoles store materials, the cell membrane regulates the movement of substances in and out of the cell, and ribosomes are involved in protein synthesis.
5. In order, from lower to upper, the layers of the atmosphere are:
- A. Exosphere, thermosphere, mesosphere, stratosphere, troposphere
- B. Troposphere, stratosphere, mesosphere, thermosphere, exosphere
- C. Mesosphere, troposphere, stratosphere, thermosphere, exosphere
- D. Thermosphere, troposphere, stratosphere, mesosphere, exosphere
Correct answer: B
Rationale: The correct order of the layers of the atmosphere, from lower to upper, is troposphere, stratosphere, mesosphere, thermosphere, exosphere. The troposphere is the lowest layer where weather phenomena occur. The stratosphere contains the ozone layer, which absorbs and scatters the solar ultraviolet radiation. The mesosphere is where most meteorites burn up upon entering the Earth's atmosphere. The thermosphere is characterized by high temperatures due to the absorption of solar radiation. The exosphere is the outermost layer where the atmosphere transitions into space. Therefore, option B is the correct sequence, as it reflects the ascending order of the Earth's atmospheric layers.
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