HESI A2
Biology HESI A2 Practice Test
1. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
2. In the scientific process, which of the following is a statement or explanation of certain events or happenings?
- A. hypothesis
- B. observation
- C. experiment
- D. conclusion
Correct answer: A
Rationale: A hypothesis is a statement or explanation of certain events or phenomena based on observations and prior knowledge. It is a testable prediction that guides the scientific investigation process. By formulating a hypothesis, scientists can make predictions and design experiments to gather data and test the validity of the hypothesis. Observations (choice B) involve gathering information through the senses. Experiments (choice C) are procedures carried out to support or refute a hypothesis. Conclusions (choice D) are deductions made based on the results of experiments and observations, but they are not the initial statement or explanation of events or happenings.
3. How many bones are included in the human skeletal system?
- A. 412
- B. 103
- C. Over 300
- D. 206
Correct answer: D
Rationale: There are 206 bones in the human skeletal system. This includes bones in the skull, spine, ribs, arms, legs, hands, and feet. The correct answer is 206 because that is the standard number of bones in an adult human body. Choices A, B, and C are incorrect as they do not reflect the accurate count of bones in the human skeletal system.
4. Which cellular structure is largely protective in function?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: C
Rationale: The correct answer is C: Cell membrane. The cell membrane, also known as the plasma membrane, is largely protective in function as it serves as a selectively permeable barrier that surrounds the cell, providing structural support and helping to maintain cell integrity. It regulates the movement of substances in and out of the cell, thus protecting the cell from harmful external factors while allowing essential nutrients to enter. Mitochondrion (choice A) is responsible for energy production, not primarily protective. Vacuole (choice B) is mainly involved in storage and transport. Ribosome (choice D) is involved in protein synthesis, not protective functions.
5. What happens to messenger RNA when it reaches the cytoplasm?
- A. It attaches to a ribosome.
- B. It unzips, exposing nitrogen bases.
- C. It pairs with the DNA bases.
- D. It pulls free of the DNA strand.
Correct answer: A
Rationale: Messenger RNA (mRNA) carries genetic information from the DNA in the nucleus to the ribosomes in the cytoplasm. When mRNA reaches the cytoplasm, it attaches to a ribosome. The ribosome functions as the site for protein synthesis through translation, where the genetic code carried by mRNA is read and translated into a specific sequence of amino acids. Choices B, C, and D are incorrect because mRNA does not unzip, expose nitrogen bases, pair with DNA bases, or pull free of the DNA strand in the cytoplasm. The primary function of mRNA in the cytoplasm is to serve as a template for protein synthesis by binding to ribosomes.
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