HESI A2
Biology HESI A2 Practice Test
1. Which of the following is true of homozygous traits?
- A. They are haploid
- B. They are denoted AA
- C. They are denoted aa
- D. They are denoted Aa
Correct answer: B
Rationale: Homozygous traits have two identical forms of the gene, either both dominant (AA) or both recessive (aa). Therefore, choices B and C are true for homozygous traits. Choice A is incorrect because being haploid refers to having a single set of chromosomes, not necessarily homozygous traits. Choice D is incorrect as homozygous traits have identical alleles, so they are not denoted as Aa.
2. Which of the following bases is not present in RNA?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: B
Rationale: Thymine is not present in RNA. RNA uses uracil as one of its bases, which pairs with adenine. In RNA, adenine does not pair with thymine as in DNA. Cytosine and guanine are the other two bases found in both RNA and DNA.
3. Humans, or Homo sapiens, are part of the family ___________.
- A. Animalia
- B. Hominidae
- C. Mammalia
- D. Chordata
Correct answer: B
Rationale: Humans, or Homo sapiens, are part of the family Hominidae, which includes great apes such as gorillas, chimpanzees, and orangutans. This family belongs to the order Primates within the class Mammalia. Choice A (Animalia) refers to the animal kingdom, not the family of humans. Choice C (Mammalia) is the class to which the family Hominidae belongs, not the family itself. Choice D (Chordata) is the phylum to which humans and other animals with a notochord belong, not the specific family.
4. Why do high-salt content foods not require refrigeration to prevent spoilage?
- A. Osmosis
- B. Diffusion
- C. Active transport
- D. Passive transport
Correct answer: A
Rationale: Osmosis is the natural process that prevents high-salt content foods from spoiling without the need for refrigeration. Osmosis involves the movement of water across a semi-permeable membrane from an area of lower solute concentration (water) to an area of higher solute concentration (salt). In high-salt content foods, the salt acts as a preservative by drawing moisture out of bacteria or other microorganisms, making it difficult for them to survive and spoil the food. This process helps in preserving the food and preventing spoilage even without refrigeration. Choices B, C, and D are incorrect because they do not involve the specific mechanism of water movement in response to the salt concentration in high-salt content foods.
5. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
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