HESI A2
Biology HESI A2 Practice Test
1. Which of the following is true of homozygous traits?
- A. They are haploid
- B. They are denoted AA
- C. They are denoted aa
- D. They are denoted Aa
Correct answer: B
Rationale: Homozygous traits have two identical forms of the gene, either both dominant (AA) or both recessive (aa). Therefore, choices B and C are true for homozygous traits. Choice A is incorrect because being haploid refers to having a single set of chromosomes, not necessarily homozygous traits. Choice D is incorrect as homozygous traits have identical alleles, so they are not denoted as Aa.
2. What happens to glucose during glycolysis?
- A. Its energy is entirely lost.
- B. It splits into molecules of pyruvic acid.
- C. It is stored in NADH.
- D. It joins with molecules of citric acid.
Correct answer: B
Rationale: During glycolysis, glucose undergoes a series of enzymatic reactions in the cytoplasm of the cell, resulting in its breakdown into two molecules of pyruvic acid. This process also generates ATP and NADH as energy carriers. Choice A is incorrect because glucose is not entirely lost, but rather converted into other molecules. Choice C is incorrect because NADH is a product of glycolysis, not a storage form for glucose. Choice D is incorrect as glucose does not join with molecules of citric acid during glycolysis, but rather in subsequent stages of cellular respiration.
3. Muscles are connected to bones by ______, and bones are connected to each other by ______.
- A. Muscles
- B. Tendons, ligaments
- C. Muscles
- D. Ligaments
Correct answer: B
Rationale: Muscles are connected to bones by tendons, which allow the muscle to exert force on the bone for movement. Bones are connected to each other by ligaments, which provide stability and support to the joints between bones. This relationship between muscles, tendons, bones, and ligaments is essential for proper movement and function of the musculoskeletal system. Choice A is incorrect because muscles are not directly connected to bones; tendons serve as the connection between muscles and bones. Choice D is incorrect because ligaments connect bones to each other, not muscles to bones.
4. What event occurs during telophase?
- A. The nuclear envelope disappears.
- B. Organelles double in number.
- C. Chromosomes separate.
- D. Two nuclei are formed.
Correct answer: D
Rationale: During telophase, the final stage of mitosis, the separated chromosomes reach opposite poles of the cell. At this stage, a new nuclear envelope forms around each set of chromosomes, creating two distinct nuclei. This marks the completion of cell division. Choices A, B, and C are incorrect because the disappearance of the nuclear envelope typically occurs during prophase, organelles do not double in number during telophase, and chromosomes separate during anaphase, not telophase.
5. Which statement is untrue?
- A. RNA is single-stranded.
- B. RNA contains uracil.
- C. DNA codes for proteins.
- D. DNA cannot be altered.
Correct answer: D
Rationale: DNA can be altered through various processes such as mutations, genetic engineering, and epigenetic modifications. Changes in DNA can occur naturally or through external influences, leading to variations in the genetic code. Therefore, the statement that DNA cannot be altered is untrue. Choices A, B, and C are true statements. RNA is indeed single-stranded, RNA contains uracil instead of thymine, and DNA serves as a template for protein synthesis.
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