HESI A2
Biology HESI A2 Practice Test
1. Tonicity refers to the movement of:
- A. Water
- B. Solute
- C. Cells
- D. None of the above
Correct answer: A
Rationale: Tonicity refers to the movement of water across a membrane in response to differences in solute concentration. In a hypertonic solution, where there is a higher concentration of solutes outside the cell, water will move out of the cell to try to reach equilibrium. In a hypotonic solution, where there is a lower concentration of solutes outside the cell, water will move into the cell to balance the concentrations. Cells and solutes themselves do not actively move in response to tonicity; it is the movement of water that helps achieve equilibrium. Therefore, the correct answer is water (Choice A). Choices B, C, and D are incorrect as tonicity specifically refers to water movement and not the movement of solutes, cells, or none of the above.
2. Ocean waves may tear sponges into pieces, each of which may grow into a new sponge. What is this form of reproduction called?
- A. Budding
- B. Vegetative propagation
- C. Binary fission
- D. Fragmentation
Correct answer: D
Rationale: Fragmentation is the form of asexual reproduction where an organism breaks into fragments, and each fragment can grow into a new individual. In the case of sponges being torn into pieces by ocean waves, each piece has the potential to develop into a new sponge, making fragmentation the correct answer in this scenario. Budding is a form of asexual reproduction where a new organism develops as an outgrowth from the parent organism. Vegetative propagation involves the growth of new individuals from plant parts like stems or roots. Binary fission is a method of reproduction seen in some single-celled organisms where one cell divides into two identical cells.
3. Which of the following are considered the most important molecules in biology?
- A. Carbohydrates, lipids, protein, and nucleic acids
- B. Carbohydrates, lipids, protein, and calcium
- C. Carbohydrates, lipids, protein, and sulfur
- D. Carbohydrates, lipids, protein, and iron
Correct answer: A
Rationale: The correct answer is A: Carbohydrates, lipids, protein, and nucleic acids are considered the most important molecules in biology. Carbohydrates are essential for providing energy, lipids for storing energy and forming cell membranes, proteins for various structural and functional roles, and nucleic acids (DNA and RNA) for storing genetic information. Choices B, C, and D are incorrect because while carbohydrates, lipids, and proteins are crucial biomolecules, calcium, sulfur, and iron are not considered among the most important molecules in biology.
4. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
5. What type of transport moves substances across the cell membrane using energy?
- A. Passive Transport
- B. Active Transport
- C. Facilitated Diffusion
- D. Osmosis
Correct answer: B
Rationale: The correct answer is B: Active Transport. Active transport moves substances across the cell membrane by utilizing energy from the cell, typically in the form of ATP. This process allows the cell to move molecules against their concentration gradient, requiring energy expenditure. Choices A, C, and D are incorrect because passive transport does not require energy input, facilitated diffusion involves the assistance of proteins but does not directly use energy, and osmosis is the diffusion of water molecules specifically, not substances, across a selectively permeable membrane.
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