HESI A2
Biology HESI A2 Practice Test
1. Tonicity refers to the movement of:
- A. Water
- B. Solute
- C. Cells
- D. None of the above
Correct answer: A
Rationale: Tonicity refers to the movement of water across a membrane in response to differences in solute concentration. In a hypertonic solution, where there is a higher concentration of solutes outside the cell, water will move out of the cell to try to reach equilibrium. In a hypotonic solution, where there is a lower concentration of solutes outside the cell, water will move into the cell to balance the concentrations. Cells and solutes themselves do not actively move in response to tonicity; it is the movement of water that helps achieve equilibrium. Therefore, the correct answer is water (Choice A). Choices B, C, and D are incorrect as tonicity specifically refers to water movement and not the movement of solutes, cells, or none of the above.
2. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
3. What organelle do plant cells have that functions as storage, waste disposal, and protection?
- A. Nucleus
- B. Mitochondria
- C. Vacuoles
- D. Ribosomes
Correct answer: C
Rationale: Correct! Plant cells have vacuoles that serve as storage centers, help in waste disposal by containing and isolating harmful materials, and contribute to protection by storing toxic substances. The other choices are incorrect because the nucleus contains genetic material, mitochondria are responsible for energy production, and ribosomes are involved in protein synthesis.
4. What happens to messenger RNA when it reaches the cytoplasm?
- A. It attaches to a ribosome.
- B. It unzips, exposing nitrogen bases.
- C. It pairs with the DNA bases.
- D. It pulls free of the DNA strand.
Correct answer: A
Rationale: Messenger RNA (mRNA) carries genetic information from the DNA in the nucleus to the ribosomes in the cytoplasm. When mRNA reaches the cytoplasm, it attaches to a ribosome. The ribosome functions as the site for protein synthesis through translation, where the genetic code carried by mRNA is read and translated into a specific sequence of amino acids. Choices B, C, and D are incorrect because mRNA does not unzip, expose nitrogen bases, pair with DNA bases, or pull free of the DNA strand in the cytoplasm. The primary function of mRNA in the cytoplasm is to serve as a template for protein synthesis by binding to ribosomes.
5. Why doesn't an antibiotic work for treating the flu?
- A. The antibiotic is for a different type of infection
- B. The antibiotic is not effective against viruses
- C. The antibiotic is not prescribed in a high enough dosage
- D. None of the above
Correct answer: B
Rationale: The correct answer is B. Antibiotics are used to treat bacterial infections, not viral infections like the flu. The flu is caused by a virus, and antibiotics are ineffective against viruses. Choice A is incorrect because it does not address the fact that antibiotics do not work on viruses. Choice C is incorrect as the issue is not related to the dosage amount, but rather the nature of the infection. Choice D is incorrect as there is a specific reason why antibiotics do not work for the flu.
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