HESI A2
Biology HESI A2 Practice Test
1. Tonicity refers to the movement of:
- A. Water
- B. Solute
- C. Cells
- D. None of the above
Correct answer: A
Rationale: Tonicity refers to the movement of water across a membrane in response to differences in solute concentration. In a hypertonic solution, where there is a higher concentration of solutes outside the cell, water will move out of the cell to try to reach equilibrium. In a hypotonic solution, where there is a lower concentration of solutes outside the cell, water will move into the cell to balance the concentrations. Cells and solutes themselves do not actively move in response to tonicity; it is the movement of water that helps achieve equilibrium. Therefore, the correct answer is water (Choice A). Choices B, C, and D are incorrect as tonicity specifically refers to water movement and not the movement of solutes, cells, or none of the above.
2. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
3. What organelle do plant cells have that functions as storage, waste disposal, and protection?
- A. Nucleus
- B. Mitochondria
- C. Vacuoles
- D. Ribosomes
Correct answer: C
Rationale: Correct! Plant cells have vacuoles that serve as storage centers, help in waste disposal by containing and isolating harmful materials, and contribute to protection by storing toxic substances. The other choices are incorrect because the nucleus contains genetic material, mitochondria are responsible for energy production, and ribosomes are involved in protein synthesis.
4. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
5. Which organelle is the site of energy production?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion. The mitochondrion is the site of energy production in a cell. It is often referred to as the powerhouse of the cell because it is where cellular respiration occurs, generating energy in the form of adenosine triphosphate (ATP) through processes like the citric acid cycle and oxidative phosphorylation. The other organelles listed play different roles in the cell - vacuoles store materials, the cell membrane regulates the movement of substances in and out of the cell, and ribosomes are involved in protein synthesis.
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