HESI A2
Biology HESI A2 Practice Exam
1. RNA is made from DNA through a process called ___________.
- A. transcription
- B. synthesis
- C. translation
- D. replication
Correct answer: A
Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.
2. What is the term for the movement of ions and other molecular substances across cell membranes without the need for energy?
- A. Active Transport
- B. Passive Transport
- C. Diffusion
- D. Osmosis
Correct answer: B
Rationale: Passive transport refers to the movement of substances across cell membranes without the need for energy input. In contrast, active transport, choice A, requires energy to move substances against their concentration gradient. Diffusion, choice C, is a type of passive transport where substances move from an area of high concentration to low concentration. Osmosis, choice D, specifically refers to the movement of water molecules across a selectively permeable membrane.
3. Where is the slide typically placed on a microscope?
- A. Eyepiece
- B. Stage
- C. Focus knob
- D. Objective lens
Correct answer: B
Rationale: The slide is typically placed on the stage of a microscope. The stage is the platform where the slide containing the specimen is positioned for viewing. The eyepiece is where you look through to view the specimen, the focus knob is used to sharpen the image, and the objective lens is responsible for magnification. Therefore, the correct answer is the stage.
4. In which phase of mitosis do new nuclear membranes form around sets of chromosomes?
- A. Prophase
- B. Anaphase
- C. Telophase
- D. Interphase
Correct answer: C
Rationale: The correct answer is C, Telophase. During telophase, the final phase of mitosis, new nuclear membranes form around sets of chromosomes at the opposite poles of the cell. This process marks the completion of nuclear division in mitosis. Choices A, B, and D are incorrect because in prophase, chromosomes condense but nuclear membranes are not formed; in anaphase, chromosomes separate and move to opposite poles but no new nuclear membranes are formed; and in interphase, the cell prepares for division but nuclear membranes are not forming around sets of chromosomes.
5. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
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