HESI A2
Biology HESI A2 Practice Exam
1. RNA is made from DNA through a process called ___________.
- A. transcription
- B. synthesis
- C. translation
- D. replication
Correct answer: A
Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.
2. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
3. In contrast with triglycerides, phospholipids are lacking one of which of the following components?
- A. Monosaccharide
- B. Glycerol
- C. Phosphates
- D. Fatty acid
Correct answer: B
Rationale: Phospholipids are structurally similar to triglycerides but lack one of the fatty acid chains that triglycerides possess. Triglycerides consist of three fatty acid chains attached to a glycerol molecule, while phospholipids have two fatty acid chains and a phosphate group attached to a glycerol backbone. Therefore, phospholipids are lacking the third fatty acid chain found in triglycerides. Choice A (Monosaccharide) is incorrect because neither triglycerides nor phospholipids contain monosaccharides in their structure. Choice C (Phosphates) is incorrect because phospholipids actually contain phosphates, unlike triglycerides. Choice D (Fatty acid) is incorrect as both triglycerides and phospholipids contain fatty acids, but the number of fatty acid chains differs between the two.
4. What type of transport moves substances across the cell membrane using energy?
- A. Passive Transport
- B. Active Transport
- C. Facilitated Diffusion
- D. Osmosis
Correct answer: B
Rationale: The correct answer is B: Active Transport. Active transport moves substances across the cell membrane by utilizing energy from the cell, typically in the form of ATP. This process allows the cell to move molecules against their concentration gradient, requiring energy expenditure. Choices A, C, and D are incorrect because passive transport does not require energy input, facilitated diffusion involves the assistance of proteins but does not directly use energy, and osmosis is the diffusion of water molecules specifically, not substances, across a selectively permeable membrane.
5. Which two bases are purines?
- A. Adenine (A)
- B. Cytosine (C)
- C. Thymine (T)
- D. Guanine (G)
Correct answer: A
Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.
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