HESI A2
Biology HESI A2 2024
1. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
2. What is the composition of the plasma membrane?
- A. Proteins
- B. Lipids
- C. Carbohydrates
- D. Nucleotides
Correct answer: B
Rationale: The plasma membrane is composed of lipids, proteins, and carbohydrates. While proteins are an essential component of the plasma membrane, it is not the only constituent. Carbohydrates and lipids also play crucial roles in the structure and function of the plasma membrane. Nucleotides are not part of the primary structural components of the plasma membrane, making this choice incorrect.
3. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
4. Which of the following cell types has no nucleus?
- A. platelet
- B. red blood cell
- C. white blood cell
- D. phagocyte
Correct answer: B
Rationale: The correct answer is B, red blood cell. In humans, red blood cells do not have a nucleus. This unique feature allows them to have more space to carry oxygen efficiently. Platelets (choice A), white blood cells (choice C), and phagocytes (choice D) all have nuclei. Platelets are cell fragments, while white blood cells and phagocytes are types of immune cells that contain a nucleus for DNA and cellular functions.
5. What is the purpose of the mitochondria?
- A. Control the cell
- B. Create energy
- C. Create proteins
- D. Package waste for removal
Correct answer: B
Rationale: The correct answer is B: Create energy. The primary purpose of the mitochondria is to generate energy for the cell. Mitochondria are known as the 'powerhouses' of the cell because they produce ATP (adenosine triphosphate), which is the energy currency used by cells to carry out various functions and processes. Choice A is incorrect as the mitochondria do not control the cell but rather produce energy. Choice C is incorrect as protein synthesis primarily occurs in the ribosomes. Choice D is incorrect as packaging waste for removal is a function associated with lysosomes, not mitochondria.
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