HESI A2
Biology HESI A2 2024
1. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
2. Which cells in the human body lack nuclei?
- A. Nerve cells
- B. Red blood cells
- C. Liver cells
- D. Connective tissue cells
Correct answer: B
Rationale: Red blood cells, also known as erythrocytes, lack nuclei in humans. This absence of a nucleus allows more space for hemoglobin, the protein responsible for carrying oxygen, making red blood cells efficient at their function of oxygen transport in the body. Nerve cells (Choice A), liver cells (Choice C), and connective tissue cells (Choice D) all possess nuclei as they require genetic material for their functions, such as cell signaling, protein synthesis, and structural support.
3. Which of the following is an example of human error in an experiment?
- A. an imperfectly calibrated scale
- B. contaminating a sterile sample by breathing on it
- C. a draft in the laboratory slightly changing the temperature of a liquid
- D. failure to account for wind speed when measuring distance traveled
Correct answer: B
Rationale: Contaminating a sterile sample by breathing on it is an example of human error in an experiment because it involves an action directly caused by the researcher that compromises the integrity of the sample. Breathing on a sterile sample introduces external contaminants that can affect the results. Choices A, C, and D involve factors not directly under the researcher's control or are technical errors that do not involve direct human actions.
4. Prokaryotic cells:
- A. Have a nucleus
- B. Have a capsule
- C. Have membrane-bound organelles
- D. Cannot move on their own
Correct answer: B
Rationale: Prokaryotic cells do not have a nucleus or membrane-bound organelles. One characteristic feature of prokaryotic cells is the presence of a capsule, which is a protective layer outside the cell wall. This capsule helps the prokaryotic cell adhere to surfaces, evade the host immune system, and protect against desiccation. Choice A is incorrect because prokaryotic cells lack a nucleus. Choice C is incorrect as prokaryotic cells do not have membrane-bound organelles. Choice D is incorrect as prokaryotic cells can move using structures like flagella or pili.
5. Enzymes can _ reactions.
- A. Catalyze
- B. Inhibit
- C. Stop
- D. None of the above
Correct answer: A
Rationale: Enzymes function as catalysts that promote and accelerate chemical reactions in biological systems. They do this by lowering the activation energy required for the reactions to occur, thereby speeding up the process without being consumed in the reaction. Enzymes facilitate reactions rather than inhibiting or stopping them. Therefore, the correct answer is 'Catalyze.' 'Inhibit' and 'Stop' are incorrect because enzymes do not hinder or halt reactions but rather enhance them.
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