HESI A2
Biology HESI A2 2024
1. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
2. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
3. Why are bacteria and blue-green algae often classified together?
- A. Both are gymnosperms.
- B. Both are prokaryotes.
- C. Both are autotrophs.
- D. Both are pathogens.
Correct answer: B
Rationale: Bacteria and blue-green algae (cyanobacteria) are often classified together because they are both prokaryotes. Prokaryotes are unicellular organisms that lack a membrane-bound nucleus and other membrane-bound organelles. This characteristic distinguishes them from eukaryotic organisms, which have these membrane-bound structures. Choice A is incorrect because gymnosperms are seed-producing plants with naked seeds, not bacteria or blue-green algae. Choice C is incorrect because being an autotroph (able to produce its own food) is not a reason for classifying them together. Choice D is incorrect because not all bacteria and blue-green algae are pathogens; many of them are beneficial or neutral to other organisms.
4. Where is the site of cellular respiration in eukaryotic cells?
- A. Nucleus
- B. Chloroplasts
- C. Mitochondria
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C: Mitochondria. Mitochondria are often referred to as the powerhouse of the cell because they are responsible for cellular respiration in eukaryotic cells. During cellular respiration, mitochondria generate energy in the form of ATP. Choices A, B, and D are incorrect. The nucleus is the organelle that houses the cell's genetic material, chloroplasts are responsible for photosynthesis in plant cells, and ribosomes are involved in protein synthesis, not cellular respiration.
5. Why do cells need to use exocytosis?
- A. To obtain energy
- B. To defend against invaders
- C. To remove waste products
- D. To undergo division
Correct answer: C
Rationale: Cells need to use exocytosis to remove waste products from the cell. Exocytosis is a process where cells release molecules or substances outside the cell by fusing vesicles with the cell membrane. This process is crucial for maintaining cellular homeostasis by efficiently eliminating waste materials. Choices A, B, and D are incorrect because exocytosis is specifically involved in the expulsion of molecules, not for obtaining energy, defending against invaders, or cell division.
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