HESI A2
Biology HESI A2 Practice Test
1. DNA bases include all but which of the following?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is not a DNA base; it is a base found only in RNA. The four bases in DNA are Adenine, Thymine, Cytosine, and Guanine. Choice A, Adenine, is a correct DNA base. Choice B, Thymine, is a correct DNA base. Choice D, Cytosine, is a correct DNA base. Therefore, Uracil is the only incorrect choice among the options provided.
2. Which organelle is responsible for organizing protein synthesis?
- A. Nucleus
- B. Ribosome
- C. Lysosome
- D. Vacuole
Correct answer: B
Rationale: The correct answer is B: Ribosome. Ribosomes are responsible for organizing protein synthesis by assembling amino acids. They are the cellular machinery where proteins are synthesized. The other choices, such as the nucleus, lysosome, and vacuole, do not directly participate in protein synthesis. The nucleus contains DNA and controls cell activities, the lysosome is involved in digestion and waste removal, and the vacuole is responsible for storage and maintaining cell turgor pressure.
3. Which of the following describes how a bacterium reproduces?
- A. Mitosis
- B. Meiosis
- C. Binary fission
- D. Cytokinesis
Correct answer: C
Rationale: Bacteria reproduce through a process called 'binary fission.' During binary fission, a bacterium duplicates its DNA and then divides into two identical daughter cells. This method is the primary way bacteria replicate. Choice A, 'Mitosis,' is incorrect because mitosis is a process specific to eukaryotic cells, where the nucleus divides to produce two identical nuclei. Choice B, 'Meiosis,' is incorrect as meiosis is a specialized type of cell division that produces gametes with half the chromosome number. Choice D, 'Cytokinesis,' is not the correct answer as cytokinesis is the physical process of cell division, which occurs after the genetic material has been divided in mitosis or meiosis.
4. What happens during anaphase?
- A. Chromosomes move to opposite ends of the spindle.
- B. Nuclear membrane and nucleoli disintegrate.
- C. Chromatids line up at the center of the spindle.
- D. Nuclear membrane and nucleoli form.
Correct answer: A
Rationale: During anaphase, the sister chromatids, joined at the centromere, separate and move towards opposite ends of the spindle apparatus. This movement ensures that each daughter cell receives an identical set of chromosomes. Choice B is incorrect as the disintegration of the nuclear membrane and nucleoli occurs during prophase. Choice C is incorrect as chromatids align at the center of the spindle during metaphase, not anaphase. Choice D is incorrect as the formation of the nuclear membrane and nucleoli occurs during telophase, not anaphase.
5. Which is not part of a nucleic acid?
- A. Sulfate
- B. Phosphate
- C. Carbon
- D. Nitrogen
Correct answer: A
Rationale: Sulfate is not part of a nucleic acid. Nucleic acids, such as DNA and RNA, are composed of nucleotide units, which consist of a phosphate group, a sugar molecule (ribose in RNA and deoxyribose in DNA), and a nitrogenous base. Carbon and nitrogen are essential elements found in nucleic acids, while sulfate is not a component of nucleic acid structure. Therefore, the correct answer is A: Sulfate.
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