HESI A2
HESI A2 Biology 2024
1. What happens to glucose during glycolysis?
- A. Its energy is entirely lost.
- B. It splits into molecules of pyruvic acid.
- C. It is stored in NADH.
- D. It joins with molecules of citric acid.
Correct answer: B
Rationale: During glycolysis, glucose undergoes a series of enzymatic reactions in the cytoplasm of the cell, resulting in its breakdown into two molecules of pyruvic acid. This process also generates ATP and NADH as energy carriers. Choice A is incorrect because glucose is not entirely lost, but rather converted into other molecules. Choice C is incorrect because NADH is a product of glycolysis, not a storage form for glucose. Choice D is incorrect as glucose does not join with molecules of citric acid during glycolysis, but rather in subsequent stages of cellular respiration.
2. What organelle pushes water out of the cell?
- A. Lysosomes
- B. Vacuoles (contractile)
- C. Mitochondria
- D. Nucleus
Correct answer: B
Rationale: The correct answer is B: Vacuoles (contractile). Vacuoles (contractile) are responsible for expelling excess water out of the cell. Lysosomes are involved in the digestion and removal of waste materials, mitochondria are the powerhouse of the cell involved in energy production, and the nucleus contains the cell's genetic material but does not play a role in pushing water out of the cell.
3. How does yeast reproduce?
- A. Binary fission
- B. Spore formation
- C. Budding
- D. Cloning
Correct answer: C
Rationale: Yeast typically reproduces through a process called budding. During budding, a small outgrowth forms on the parent yeast cell, gradually enlarging in size until it separates to become a new, genetically identical daughter cell. This method of reproduction allows yeast to rapidly multiply and grow in favorable conditions. It is different from binary fission, spore formation, and cloning. Binary fission involves the division of a single organism into two genetically identical organisms. Spore formation is a method seen in certain fungi where specialized cells develop into spores for reproduction. Cloning involves producing genetically identical copies of an organism. Therefore, budding is the correct answer for how yeast reproduces.
4. Which of the following types of hormones can diffuse through the cell membrane to bind to receptors inside the cell and stimulate a chemical response to a target cell?
- A. fat-soluble hormones
- B. amino acid derivatives
- C. hydrophilic hormones
- D. water-soluble hormones
Correct answer: A
Rationale: The correct answer is A: fat-soluble hormones. Fat-soluble hormones are able to diffuse through the cell membrane to bind to receptors inside the cell. This is because they are lipophilic, allowing them to cross the lipid bilayer easily. Once inside the cell, fat-soluble hormones can directly affect gene expression or cell function. Choice B, amino acid derivatives, and choice C, hydrophilic hormones, are not able to diffuse through the cell membrane as they are not lipophilic. Therefore, they cannot bind to receptors inside the cell. Choice D, water-soluble hormones, also cannot diffuse through the cell membrane as it is hydrophilic, making it unable to reach receptors inside the cell.
5. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
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