HESI A2
Biology HESI A2 2024
1. How should a researcher test the hypothesis that eating chocolate leads to acne in teenagers?
- A. Take 100 teenagers and feed each one a different amount of chocolate daily for 60 days; then test for acne.
- B. Take 100 teenagers and feed 50 two bars of chocolate daily for 60 days while the other 50 eat no chocolate; then test for acne.
- C. Take 1 teenager and feed him or her two bars of chocolate for 30 days and no chocolate for 30 days; then test for acne.
- D. Take 100 teenagers and feed them no chocolate for 30 days and two bars of chocolate apiece for 30 days; then test for acne.
Correct answer: B
Rationale: Option B is the correct approach to test the hypothesis that eating chocolate leads to acne in teenagers. This method involves having a control group (50 teenagers not consuming chocolate) and an experimental group (50 teenagers consuming two bars of chocolate daily), which allows for comparison. By having two distinct groups, researchers can assess the impact of chocolate consumption on acne development. Option A lacks a control group for comparison, making it harder to attribute any observed effects specifically to chocolate consumption. Option C only involves a single subject, which limits the generalizability of the results. Option D, where all teenagers experience both conditions, does not allow for a direct comparison between chocolate consumption and acne development, as all subjects are exposed to both conditions.
2. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
3. The difference between diploid and haploid is as follows:
- A. Diploid organisms are multicellular
- B. Diploid cells are somatic
- C. Diploid cells have two sets of homologous chromosomes
- D. More than one of the above is true
Correct answer: D
Rationale: Option B correctly states that diploid cells are somatic cells that make up the body tissues and organs in an organism, while haploid cells are gametes involved in sexual reproduction. Option C accurately differentiates diploid and haploid cells based on their chromosome sets – diploid cells have two sets of homologous chromosomes (one from each parent), whereas haploid cells have one set of unpaired chromosomes. Therefore, the correct choice is D, as both statements in options B and C are accurate descriptions of the differences between diploid and haploid cells. Option A is incorrect because diploid and haploid refer to the number of sets of chromosomes in a cell, not whether the organism is multicellular or not.
4. A cell from heart muscle would more than likely contain an unusually high proportion of which of the following?
- A. lysosomes
- B. mitochondria
- C. mRNA
- D. ribosomes
Correct answer: B
Rationale: A cell from heart muscle would more than likely contain an unusually high proportion of mitochondria because the heart muscle requires a significant amount of energy to function properly. Mitochondria are the powerhouse of the cell and are responsible for producing energy in the form of ATP through cellular respiration. Therefore, to meet the high energy demands of the heart muscle, it would need a higher concentration of mitochondria compared to other cell types. Choices A, C, and D are incorrect because while lysosomes, mRNA, and ribosomes are essential components of a cell, they do not play as direct a role in meeting the high energy demands of heart muscle as mitochondria do.
5. Which of the following organelles is responsible for producing ATP in cells?
- A. Nucleus
- B. Mitochondrion
- C. Chloroplast
- D. Lysosome
Correct answer: B
Rationale: The correct answer is 'Mitochondrion.' Mitochondria are known as the powerhouse of the cell and are responsible for producing ATP, the energy currency of the cell. The nucleus is responsible for storing genetic material and controlling cell activities, not for ATP production. Chloroplasts are found in plant cells and are responsible for photosynthesis, not ATP production. Lysosomes are involved in digestion and waste removal, not ATP production.
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