HESI A2
HESI A2 Practice Test Biology
1. How many different types of nucleotides are there in DNA?
- A. one
- B. two
- C. four
- D. eight
Correct answer: C
Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.
2. What is the typical result of mitosis in humans?
- A. two diploid cells
- B. two haploid cells
- C. four diploid cells
- D. four haploid cells
Correct answer: A
Rationale: The correct answer is A: two diploid cells. Mitosis is a type of cell division that results in two daughter cells, each having the same number of chromosomes as the parent cell. In humans, the typical result of mitosis is the formation of two diploid cells, not haploid or four cells. Choice B, two haploid cells, is incorrect because mitosis produces genetically identical diploid cells. Choices C and D, four diploid cells and four haploid cells, respectively, are incorrect as mitosis results in two daughter cells, not four.
3. Which statement is untrue?
- A. RNA is single-stranded.
- B. RNA contains uracil.
- C. DNA codes for proteins.
- D. DNA cannot be altered.
Correct answer: D
Rationale: DNA can be altered through various processes such as mutations, genetic engineering, and epigenetic modifications. Changes in DNA can occur naturally or through external influences, leading to variations in the genetic code. Therefore, the statement that DNA cannot be altered is untrue. Choices A, B, and C are true statements. RNA is indeed single-stranded, RNA contains uracil instead of thymine, and DNA serves as a template for protein synthesis.
4. What kind of bond connects sugar and phosphate in DNA?
- A. hydrogen
- B. ionic
- C. covalent
- D. overt
Correct answer: C
Rationale: Sugar and phosphate are indeed connected by covalent bonds in DNA. Covalent bonds involve the sharing of electrons between atoms, which is essential for forming the backbone of the DNA molecule. Hydrogen bonds (Choice A) are important in holding the nitrogenous bases together in the DNA double helix but do not connect sugar and phosphate. Ionic bonds (Choice B) involve the transfer of electrons between atoms and are not the primary bond connecting sugar and phosphate in DNA. 'Overt' (Choice D) is not a type of chemical bond and is an incorrect distractor.
5. Which structure might be described as a core of nucleic acid surrounded by a protein coat?
- A. RNA
- B. Virus
- C. Blue-green alga
- D. Saprophyte
Correct answer: B
Rationale: A virus can be described as a core of nucleic acid (either RNA or DNA) surrounded by a protein coat, known as a capsid. This structure distinguishes viruses from other microorganisms such as blue-green algae (Cyanobacteria), fungi known as saprophytes, or individual RNA molecules. Viruses depend on a host cell to replicate and are considered non-living entities due to their inability to carry out metabolic functions independently.
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