Nursing Elites

1. What are fingernails and toenails primarily made of?

• A. Collagen (Collagen is found in the dermis)
• B. Keratin
• C. Melanin (Melanin provides pigment, not structure)
• D. Sebum (Sebum is an oily substance)

Correct answer: B

Rationale: Fingernails and toenails are primarily made of a protein called keratin. Keratin is a tough, fibrous protein that provides structure and strength to nails, hair, and the outer layer of skin. Collagen, as mentioned, is found in the dermis and is not the primary component of nails. Melanin provides pigment to the skin and hair, not the structure of nails. Sebum is an oily substance produced by the skin's sebaceous glands and is not a structural component of nails.

2. Which vitamin is essential for collagen production, a key component of connective tissues?

• A. Vitamin A
• B. Vitamin C
• C. Vitamin D
• D. Vitamin E

Correct answer: B

Rationale: Vitamin C is essential for collagen production, a key component of connective tissues. Collagen, a crucial protein, provides structure and strength to various body tissues, such as skin, tendons, ligaments, and blood vessels. Vitamin C plays a pivotal role in collagen synthesis by aiding in the hydroxylation of proline and lysine residues, which is essential for stabilizing the collagen structure. A deficiency in vitamin C can lead to impaired collagen production, resulting in conditions like scurvy, characterized by weakened connective tissues. Vitamin A (Choice A) is important for vision and immune function but is not directly involved in collagen production. Vitamin D (Choice C) is essential for calcium absorption and bone health but is not primarily responsible for collagen synthesis. Vitamin E (Choice D) acts as an antioxidant, protecting cells from damage, but it is not a key player in collagen production.

3. What is the significance of studying pedigrees in human genetics?

• A. Predicting the exact outcome of genetic crosses in humans.
• B. Tracing the inheritance of complex traits with multiple contributing genes.
• C. Identifying carriers of dominant genetic disorders.
• D. Determining the risk of acquiring a specific mutation de novo.

Correct answer: B

Rationale: Pedigrees are diagrams that show the relationships within a family and can be used to track the inheritance patterns of specific traits or diseases. While pedigrees can provide information on the inheritance of single gene disorders (such as identifying carriers of dominant genetic disorders, as mentioned in option C), their primary significance lies in studying complex traits with multiple contributing genes. These traits do not follow simple Mendelian inheritance patterns and are influenced by both genetic and environmental factors. By analyzing pedigrees, researchers can identify patterns of inheritance for complex traits, such as polygenic diseases or traits influenced by gene-environment interactions. Therefore, option B is the most appropriate choice as it captures the main significance of studying pedigrees in human genetics.

4. What is the structure of DNA?

• A. Single-stranded, linear
• B. Double-stranded, linear
• C. Double-stranded, helix
• D. Single-stranded, helix

Correct answer: C

Rationale: The correct answer is C: Double-stranded, helix. DNA is structured as a double helix formed by two strands of nucleotides. The nucleotides are paired with complementary bases (A-T and C-G) in the center, held together by hydrogen bonds. This double-stranded helical structure is a fundamental characteristic of DNA and essential for its function in storing genetic information. Choices A, B, and D are incorrect because DNA is not single-stranded; it consists of two strands that run antiparallel to each other and are connected via hydrogen bonds. Additionally, DNA does not have a linear structure but rather a helical one, providing stability and protection to the genetic information it carries.

5. Which type of joint allows for the most movement?

• A. Ball-and-socket joint (shoulder)
• B. Hinge joint (elbow)
• C. Fibrocartilaginous joint (wrists)
• D. Suture joint (skull)

Correct answer: A

Rationale: A ball-and-socket joint allows for the most movement among the options provided. This type of joint is characterized by a rounded end of one bone fitting into a cup-like socket of another bone, allowing for a wide range of motion in multiple directions. The shoulder joint is a prime example of a ball-and-socket joint, enabling movements such as flexion, extension, abduction, adduction, and rotation. In contrast, a hinge joint (option B) like the elbow primarily allows for movement in one plane (flexion and extension). Fibrocartilaginous joints (option C) like the wrists have limited movement due to the presence of cartilage between the bones. Suture joints (option D) in the skull are immovable joints that provide structural support but do not allow for significant movement.

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