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HESI A2

Biology HESI A2 Practice Test

1. Enzymes can _ reactions.

Correct answer: A

Rationale: Enzymes function as catalysts that promote and accelerate chemical reactions in biological systems. They do this by lowering the activation energy required for the reactions to occur, thereby speeding up the process without being consumed in the reaction. Enzymes facilitate reactions rather than inhibiting or stopping them. Therefore, the correct answer is 'Catalyze.' 'Inhibit' and 'Stop' are incorrect because enzymes do not hinder or halt reactions but rather enhance them.

2. What is the term for the movement of ions and other molecular substances across cell membranes without the need for energy?

Correct answer: B

Rationale: Passive transport refers to the movement of substances across cell membranes without the need for energy input. In contrast, active transport, choice A, requires energy to move substances against their concentration gradient. Diffusion, choice C, is a type of passive transport where substances move from an area of high concentration to low concentration. Osmosis, choice D, specifically refers to the movement of water molecules across a selectively permeable membrane.

3. Which of the following is always true about molecules?

Correct answer: C

Rationale: The statement that molecules move from high concentration to low concentration without using energy is always true due to the natural process of diffusion. This movement occurs to reach equilibrium and does not require any additional energy input directly from the molecule itself. Choice A is incorrect because not all molecules can travel through all cell membranes. Choice B is incorrect as molecules typically move from high concentration to low concentration in a process known as passive transport. Choice D is incorrect as molecules are in constant motion due to factors like temperature and kinetic energy.

4. Which part of cellular respiration produces the greatest amount of ATP?

Correct answer: A

Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.

5. Which two bases are purines?

Correct answer: A

Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.

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