Nursing Elites

1. During embryonic development, all tissues originate from

• A. Epithelial tissue only
• B. Muscle tissue only
• C. Connective tissue only
• D. Embryonic germ layers

Correct answer: D

Rationale: During embryonic development, all tissues originate from the three primary germ layers: ectoderm, mesoderm, and endoderm. These germ layers give rise to various tissues and organs in the developing embryo through a process called gastrulation. Epithelial, muscle, and connective tissues are derived from these germ layers during development. Therefore, choices A, B, and C are incorrect as tissues do not originate from a single type of tissue but rather from the embryonic germ layers which differentiate into various tissues and organs.

2. What is the end product of glycolysis?

• A. Lactic acid
• B. ATP
• C. NADPH
• D. Pyruvic acid

Correct answer: D

Rationale: The correct answer is D: Pyruvic acid. The end product of glycolysis is pyruvic acid, not lactic acid, ATP, or NADPH. Pyruvic acid is a key intermediary in cellular respiration and can be further metabolized to produce energy through processes like the citric acid cycle and oxidative phosphorylation. Lactic acid is produced in the absence of oxygen during fermentation, ATP is a product of cellular respiration but not the direct end product of glycolysis, and NADPH is generated in other metabolic pathways such as the pentose phosphate pathway, not in glycolysis.

3. What checkpoint mechanism ensures all chromosomes are attached to the spindle fibers before anaphase begins?

• A. Prometaphase
• B. Metaphase
• C. Cyclin degradation
• D. Sister chromatid cohesion

Correct answer: A

Rationale: A) Prometaphase is the correct answer because it is the stage of mitosis where all chromosomes are attached to the spindle fibers before anaphase begins. During prometaphase, the nuclear envelope breaks down, allowing the spindle fibers to attach to the kinetochores of the chromosomes. This attachment is necessary for proper chromosome alignment and segregation during anaphase. B) Metaphase is incorrect because it is the stage where chromosomes are aligned at the metaphase plate but do not necessarily have all spindle fibers attached. C) Cyclin degradation is incorrect because it is a regulatory mechanism that controls the progression of the cell cycle but is not specifically related to ensuring all chromosomes are attached to spindle fibers. D) Sister chromatid cohesion is incorrect because it refers to the physical connection between sister chromatids that is maintained until anaphase, but it does not ensure that all chromosomes are attached to spindle fibers.

4. What term refers to the point of contact between a motor neuron and a muscle fiber, where communication occurs to initiate muscle contraction?

• A. Sarcomere
• B. Synapse
• C. Tendon
• D. Myofibril

Correct answer: B

Rationale: The correct answer is B, 'Synapse.' The synapse is the specific term that refers to the point of contact between a motor neuron and a muscle fiber, where communication occurs to initiate muscle contraction. At the synapse, neurotransmitters are released by the motor neuron, triggering the muscle fiber to contract. Choice A, 'Sarcomere,' is incorrect as a sarcomere is the basic unit of muscle contraction, not the point of contact between a motor neuron and a muscle fiber. Choice C, 'Tendon,' is incorrect as tendons are fibrous connective tissues that connect muscle to bone, not involved in neuronal communication. Choice D, 'Myofibril,' is incorrect as a myofibril is a structure within muscle fibers where muscle contractions occur, not the specific point of contact for communication between a motor neuron and a muscle fiber.

5. Which of the following enzymes unwinds the double-stranded DNA during replication?

• A. Helicase
• B. Ligase
• C. Nuclease
• D. Polymerase

Correct answer: A

Rationale: Helicase is the enzyme responsible for unwinding the double-stranded DNA during replication by breaking the hydrogen bonds between the base pairs. This process creates the replication fork where DNA polymerase can then synthesize new DNA strands. Ligase functions to join Okazaki fragments on the lagging strand, not unwind DNA. Nuclease is involved in DNA repair by removing damaged DNA segments. Polymerase is responsible for synthesizing new DNA strands based on the existing template strands, not for unwinding the DNA.

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