HESI A2
Biology HESI A2 Practice Exam
1. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
2. Which cells in the human body lack nuclei?
- A. Nerve cells
- B. Red blood cells
- C. Liver cells
- D. Connective tissue cells
Correct answer: B
Rationale: Red blood cells, also known as erythrocytes, lack nuclei in humans. This absence of a nucleus allows more space for hemoglobin, the protein responsible for carrying oxygen, making red blood cells efficient at their function of oxygen transport in the body. Nerve cells (Choice A), liver cells (Choice C), and connective tissue cells (Choice D) all possess nuclei as they require genetic material for their functions, such as cell signaling, protein synthesis, and structural support.
3. Which is not one of the raw materials needed for cellular respiration?
- A. ADP
- B. Phosphate
- C. Water
- D. Glucose
Correct answer: C
Rationale: Water is not one of the raw materials needed for cellular respiration. The essential raw materials for cellular respiration include glucose (which is broken down to produce energy), oxygen, and ADP (adenosine diphosphate) and phosphate (which are necessary for the formation of ATP, the energy currency of cells). While water is crucial for many cellular processes and makes up a significant portion of cells, it is not directly involved as a raw material in the cellular respiration process.
4. Genes control heredity in man and other organisms. This gene is ___
- A. A segment of DNA
- B. A bead-like structure on the chromosomes
- C. A protein molecule
- D. A segment of RNA
Correct answer: A
Rationale: Genes are sections of DNA that contain instructions for building and operating living organisms. These sections of DNA contain the genetic information that is passed on from one generation to the next. Genes are composed of specific sequences of nucleotides within the DNA molecule. Therefore, genes are best described as segments of DNA. Choice A is correct. Choice B is incorrect because genes are not bead-like structures on chromosomes but specific sequences of DNA. Choice C is incorrect because genes are not protein molecules but rather sequences of nucleotides. Choice D is incorrect because genes are not segments of RNA but DNA.
5. How does yeast reproduce?
- A. Binary fission
- B. Spore formation
- C. Budding
- D. Cloning
Correct answer: C
Rationale: Yeast typically reproduces through a process called budding. During budding, a small outgrowth forms on the parent yeast cell, gradually enlarging in size until it separates to become a new, genetically identical daughter cell. This method of reproduction allows yeast to rapidly multiply and grow in favorable conditions. It is different from binary fission, spore formation, and cloning. Binary fission involves the division of a single organism into two genetically identical organisms. Spore formation is a method seen in certain fungi where specialized cells develop into spores for reproduction. Cloning involves producing genetically identical copies of an organism. Therefore, budding is the correct answer for how yeast reproduces.
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