duchenne muscular dystrophy is a recessive sex linked trait carried on the x chromosome in an example of an unaffected father and a female carrier who

HESI A2

Biology HESI A2 Practice Exam

1. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?

A. Both daughters will carry the disease.
B. Both sons will carry the disease.
C. One daughter may have the disease.
D. One son may have the disease.

Correct answer: C

Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.

2. What are the two catabolic pathways that lead to cellular energy production?

A. Fermentation and internal respiration
B. Fermentation and external respiration
C. Fermentation and cellular respiration
D. Fermentation and anaerobic respiration

Correct answer: C

Rationale: The correct answer is 'Fermentation and cellular respiration.' Fermentation is an anaerobic catabolic process that occurs in the absence of oxygen, producing limited amounts of ATP. Cellular respiration, on the other hand, is the aerobic catabolic pathway that occurs in the presence of oxygen and is the most efficient way of producing ATP. Choices A, B, and D are incorrect because internal respiration, external respiration, and anaerobic respiration are not the correct pathways leading to cellular energy production.

3. What happens to messenger RNA when it reaches the cytoplasm?

A. It attaches to a ribosome.
B. It unzips, exposing nitrogen bases.
C. It pairs with the DNA bases.
D. It pulls free of the DNA strand.

Correct answer: A

Rationale: Messenger RNA (mRNA) carries genetic information from the DNA in the nucleus to the ribosomes in the cytoplasm. When mRNA reaches the cytoplasm, it attaches to a ribosome. The ribosome functions as the site for protein synthesis through translation, where the genetic code carried by mRNA is read and translated into a specific sequence of amino acids. Choices B, C, and D are incorrect because mRNA does not unzip, expose nitrogen bases, pair with DNA bases, or pull free of the DNA strand in the cytoplasm. The primary function of mRNA in the cytoplasm is to serve as a template for protein synthesis by binding to ribosomes.

4. 72 chromosomes undergo meiosis. How many chromosomes will be in each gamete?

A. 18
B. 36
C. 72
D. 144

Correct answer: A

Rationale: During meiosis, the number of chromosomes is halved in each gamete. Since 72 chromosomes undergo meiosis, each gamete will contain half of that number, which is 36 chromosomes. Therefore, the correct answer is 18 chromosomes in each gamete. Choice B (36 chromosomes) is incorrect because it represents the total number of chromosomes that undergo meiosis, not the number in each gamete. Choice C (72 chromosomes) is incorrect as it represents the initial number of chromosomes, not the number in each gamete after meiosis. Choice D (144 chromosomes) is incorrect as it doubles the initial number of chromosomes, which is not the outcome of meiosis.

5. Where is the genetic information of a eukaryotic cell stored?

A. Mitochondria
B. Nucleus
C. Golgi Apparatus
D. Cytoplasm

Correct answer: B

Rationale: The correct answer is B: Nucleus. In eukaryotic cells, genetic information (DNA) is stored in the nucleus. This organelle acts as the control center of the cell, housing the DNA and regulating gene expression. Choices A, C, and D are incorrect because the genetic information is not stored in the mitochondria, Golgi Apparatus, or cytoplasm. The mitochondria are responsible for energy production, the Golgi Apparatus is involved in protein processing and packaging, and the cytoplasm is where various cellular activities take place, but none of these organelles store the genetic information.