duchenne muscular dystrophy is a recessive sex linked trait carried on the x chromosome in an example of an unaffected father and a female carrier who
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HESI A2

Biology HESI A2 Practice Exam

1. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?

Correct answer: C

Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.

2. How are molecules of water bonded to each other?

Correct answer: C

Rationale: Water molecules are bonded to each other by 'hydrogen' bonds. These bonds are not as strong as covalent bonds, which hold the atoms within each water molecule together (Choice B). Ionic bonds (Choice A) involve the transfer of electrons between atoms, which is not the case in water molecules. The term 'molecular' (Choice D) is too general and doesn't specifically describe the type of bond between water molecules.

3. Why does cytokinesis happen?

Correct answer: D

Rationale: Cytokinesis happens at the end of mitosis to physically separate the newly formed daughter cells. This allows the cell to divide into two separate daughter cells, each containing a complete set of genetic material (DNA) and organelles. The purpose of cytokinesis is to ensure that each daughter cell receives the necessary components to function independently. Choices A, B, and C are incorrect because cytokinesis does not directly involve DNA duplication, organelles converting energy, or killing bacteria.

4. During which phase is the chromosome number reduced from diploid to haploid?

Correct answer: D

Rationale: The correct answer is 'meiosis I.' During meiosis I, the chromosome number is reduced from diploid to haploid through two rounds of division. Choice A ('S phase') is incorrect as the S phase is part of the cell cycle where DNA is replicated. Choice B ('interphase') is also incorrect as interphase is the phase where the cell prepares for division. Choice C ('mitosis') is incorrect as mitosis is a process where a diploid cell divides to produce two identical diploid daughter cells, maintaining the chromosome number.

5. What is the role of tRNA during protein synthesis?

Correct answer: A

Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.

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