HESI A2
Biology HESI A2 Practice Exam
1. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
2. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
3. What provides the cell with the ability to move and propel?
- A. Microfilaments
- B. Microtubules
- C. Flagella
- D. Cilia
Correct answer: B
Rationale: Microtubules are the cellular structures responsible for cell movement and propulsion. Microtubules are part of the cytoskeleton and play a crucial role in various cellular processes, including cell motility and intracellular transport. While microfilaments also contribute to cell movement by enabling muscle contraction and cell shape changes, they are not primarily responsible for propelling the cell. Flagella and cilia are cellular appendages involved in cell movement, but they are composed of microtubules, making them the structures that move due to the actions of microtubules.
4. Within the biological hierarchical system of organization, which of the following is least inclusive?
- A. phylum
- B. order
- C. kingdom
- D. species
Correct answer: D
Rationale: The correct answer is 'D: species.' In the biological hierarchical system of organization, a species is the least inclusive level. A species consists of organisms that share similar characteristics and can interbreed to produce fertile offspring. On the other hand, a phylum, order, and kingdom are more inclusive classifications that encompass multiple species. Phylum groups together related classes, order groups together related families, and kingdom groups together related phyla. Therefore, species is the least inclusive category within the biological hierarchical system.
5. Which of the following is the structure of the male reproductive system that stores spermatozoa during the maturation process?
- A. vas deferens
- B. scrotum
- C. epididymis
- D. testicular artery
Correct answer: C
Rationale: The epididymis is the structure of the male reproductive system that stores spermatozoa during the maturation process. Sperm cells produced in the testes move to the epididymis, where they mature and become motile before being ejaculated. The vas deferens is responsible for transporting mature sperm to the urethra during ejaculation, the scrotum holds the testes and helps regulate their temperature for sperm production, and the testicular artery supplies blood to the testes. Therefore, choices A, B, and D are incorrect as they do not play a direct role in storing spermatozoa during the maturation process.
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