Nursing Elites

1. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?

• A. Both daughters will carry the disease.
• B. Both sons will carry the disease.
• C. One daughter may have the disease.
• D. One son may have the disease.

Correct answer: C

Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.

2. Which of the following is not found within a bacterial cell?

• A. mitochondria
• B. DNA
• C. vesicles
• D. ribosome

Correct answer: A

Rationale: The correct answer is A: mitochondria. Mitochondria are not found in bacterial cells. Bacterial cells lack membrane-bound organelles like mitochondria, which are commonly found in eukaryotic cells. Choices B, C, and D are all components that can be found within a bacterial cell. Bacterial cells contain DNA as their genetic material, vesicles for various cellular functions, and ribosomes for protein synthesis. Therefore, the presence of mitochondria is the distinguishing factor that is not found in bacterial cells, making option A the correct answer.

3. What is the first step in the conversion of glucose to pyruvate?

• A. Glycolysis
• B. Krebs cycle
• C. Electron transport chain
• D. Aerobic respiration

Correct answer: A

Rationale: The correct answer is Glycolysis. Glycolysis is the initial step in the conversion of glucose to pyruvate. During glycolysis, glucose is broken down into pyruvate through a series of enzymatic reactions. Choice B, the Krebs cycle, occurs after glycolysis in aerobic cellular respiration. Choice C, the Electron transport chain, is the final step in aerobic respiration where the majority of ATP is produced. Choice D, Aerobic respiration, is a broader term that encompasses glycolysis, the Krebs cycle, and the electron transport chain, but it is not the specific first step in the conversion of glucose to pyruvate.

4. Which of the following is true of the Krebs cycle?

• A. It is a redox reaction involving proteins produced during glycolysis
• B. It is a redox reaction involving sugars produced during glycolysis
• C. Protons are passed along a gradient to produce ATP
• D. It is also known as the glycolic acid cycle

Correct answer: B

Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.

5. From which component do RNA and DNA derive their names?

• A. From the sugar each contains
• B. From the structure of their nucleotides
• C. From the information they transfer
• D. From their formative processes

Correct answer: A

Rationale: RNA and DNA derive their names from the sugar each contains. RNA stands for Ribonucleic Acid, with 'ribo' indicating the ribose sugar in its structure. DNA stands for Deoxyribonucleic Acid, with 'deoxyribo' referring to the deoxyribose sugar in its structure. The sugars in RNA and DNA molecules distinguish them and are the basis for their names. Choices B, C, and D are incorrect as they do not accurately explain how RNA and DNA derive their names.

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