Nursing Elites

1. Differentiate between epithelial and connective tissue.

• A. Epithelial tissue lines surfaces and glands, while connective tissue supports tendons.
• B. Both are composed of cells, but epithelial tissue lines surfaces and glands, while connective tissue binds other tissues.
• C. Epithelial tissue covers surfaces and connective tissue supports muscle contraction.
• D. Epithelial tissue is the largest tissue type, while connective tissue is the smallest.

Correct answer: B

Rationale: Epithelial tissue covers surfaces and lines organs, while connective tissue provides support and structure throughout the body. Both are composed of cells, but their functions and locations differ. Epithelial tissue acts as a barrier to protect underlying tissues and organs, while connective tissue connects, supports, and separates different types of tissues and organs in the body. Choice A is incorrect as connective tissue supports and binds other tissues, not just tendons. Choice C is incorrect because connective tissue does not support muscle contraction; it provides support to various structures in the body. Choice D is incorrect as the size of a tissue type does not define its function; epithelial tissue and connective tissue serve different purposes in the body.

2. Which of the following is NOT a type of antibody?

• A. IgA
• B. IgM
• C. Interferon
• D. IgG

Correct answer: C

Rationale: A) IgA: This is a type of antibody found in mucosal areas such as the gut, respiratory tract, and genitourinary tract. It plays a role in mucosal immunity. B) IgM: This is a type of antibody produced during the primary immune response and is the first antibody to be produced in response to an infection. C) Interferon: Interferons are signaling proteins produced by cells in response to viral infections. They play a role in the immune response by interfering with viral replication, but they are not antibodies. D) IgG: This is the most abundant type of antibody in the bloodstream and is involved in long-term immunity. Therefore, the correct answer is C) Interferon, as it is not a type of antibody.

3. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

4. Which condition involves an overactive immune system attacking healthy tissues, leading to inflammation and damage?

• A. Immunodeficiency
• B. Autoimmune disease
• C. Allergy
• D. Cancer

Correct answer: B

Rationale: Autoimmune diseases occur when the immune system mistakenly targets and attacks healthy tissues in the body, leading to inflammation and damage. This is different from immunodeficiency, where the immune system is weakened and unable to effectively protect the body against infections. Allergies involve an exaggerated immune response to harmless substances, while cancer is characterized by uncontrolled cell growth. Therefore, the correct answer is autoimmune disease (Choice B) as it specifically describes the scenario of an overactive immune system attacking healthy tissues, distinguishing it from the other conditions listed.

5. When water boils, it changes from a liquid to a gas. This is an example of a:

• A. Chemical reaction
• B. Physical change
• C. Nuclear reaction
• D. Biological process

Correct answer: B

Rationale: This is a physical change because boiling water involves a change in state from liquid to gas without altering the chemical composition of the water molecules. In a chemical reaction, new substances are formed by breaking and forming chemical bonds, which is not the case during boiling. A nuclear reaction involves changes in atomic nuclei, which are not occurring during boiling. A biological process refers to activities related to living organisms, which is not applicable to the change from liquid to gas in boiling water.

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