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HESI A2

Biology HESI A2 Practice Test

1. Muscles are connected to bones by ______, and bones are connected to each other by ______.

Correct answer: B

Rationale: Muscles are connected to bones by tendons, which allow the muscle to exert force on the bone for movement. Bones are connected to each other by ligaments, which provide stability and support to the joints between bones. This relationship between muscles, tendons, bones, and ligaments is essential for proper movement and function of the musculoskeletal system. Choice A is incorrect because muscles are not directly connected to bones; tendons serve as the connection between muscles and bones. Choice D is incorrect because ligaments connect bones to each other, not muscles to bones.

2. Which organelle contains the genetic material of the cell?

Correct answer: D

Rationale: The correct answer is 'D: Nucleus.' The nucleus is the organelle that contains the cell's genetic material, which is the DNA. The genetic material in the nucleus controls the cell's activities and plays a crucial role in inheritance. Choices A, B, and C are incorrect because the Golgi apparatus is involved in modifying, sorting, and packaging of proteins; ribosomes are involved in protein synthesis; and endoplasmic reticulum is involved in protein and lipid synthesis and transportation, but none of them contain the genetic material of the cell.

3. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

4. During which phase of mitosis does the nuclear envelope disintegrate?

Correct answer: C

Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.

5. Where is the slide typically placed on a microscope?

Correct answer: B

Rationale: The slide is typically placed on the stage of a microscope. The stage is the platform where the slide containing the specimen is positioned for viewing. The eyepiece is where you look through to view the specimen, the focus knob is used to sharpen the image, and the objective lens is responsible for magnification. Therefore, the correct answer is the stage.

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