HESI A2
Biology HESI A2 Practice Test
1. Muscles are connected to bones by ______, and bones are connected to each other by ______.
- A. Muscles
- B. Tendons, ligaments
- C. Muscles
- D. Ligaments
Correct answer: B
Rationale: Muscles are connected to bones by tendons, which allow the muscle to exert force on the bone for movement. Bones are connected to each other by ligaments, which provide stability and support to the joints between bones. This relationship between muscles, tendons, bones, and ligaments is essential for proper movement and function of the musculoskeletal system. Choice A is incorrect because muscles are not directly connected to bones; tendons serve as the connection between muscles and bones. Choice D is incorrect because ligaments connect bones to each other, not muscles to bones.
2. Patient A, who weighs 68 kilograms, steps onto a scale 20 times. The scale consistently weighs Patient A as 75 kilograms. What is true of the measurement?
- A. It is valid, but not reliable.
- B. It is reliable, but not valid.
- C. It is both valid and reliable.
- D. It is neither reliable nor valid.
Correct answer: B
Rationale: The correct answer is B: 'It is reliable, but not valid.' The measurement is reliable because it consistently provides the same result (75 kg). However, it is not valid because it does not accurately reflect the true weight of Patient A (68 kg). Choice A is incorrect because if the scale consistently shows the same weight (75 kg), it is reliable. Choice C is incorrect because although the scale is consistent, the measurement does not reflect the true weight, making it not valid. Choice D is incorrect as the measurement is reliable but lacks validity.
3. Prokaryotic cells:
- A. Have a nucleus
- B. Have a capsule
- C. Have membrane-bound organelles
- D. Cannot move on their own
Correct answer: B
Rationale: Prokaryotic cells do not have a nucleus or membrane-bound organelles. One characteristic feature of prokaryotic cells is the presence of a capsule, which is a protective layer outside the cell wall. This capsule helps the prokaryotic cell adhere to surfaces, evade the host immune system, and protect against desiccation. Choice A is incorrect because prokaryotic cells lack a nucleus. Choice C is incorrect as prokaryotic cells do not have membrane-bound organelles. Choice D is incorrect as prokaryotic cells can move using structures like flagella or pili.
4. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
5. Which of the following structures is not directly involved in translation?
- A. tRNA
- B. mRNA
- C. ribosome
- D. DNA
Correct answer: D
Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.
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