Nursing Elites

1. Which type of mutation involves a change in the number of chromosomes?

• A. Point mutation
• B. Frameshift mutation
• C. Missense mutation
• D. Aneuploidy

Correct answer: D

Rationale: A) Point mutation involves a change in a single nucleotide base pair within the DNA sequence. B) Frameshift mutation involves the insertion or deletion of nucleotides, causing a shift in the reading frame of the genetic code. C) Missense mutation involves a single nucleotide change that results in a codon that codes for a different amino acid. D) Aneuploidy involves a change in the number of chromosomes, where an individual may have an extra chromosome (trisomy) or a missing chromosome (monosomy). Aneuploidy can lead to genetic disorders such as Down syndrome (trisomy 21) or Turner syndrome (monosomy X). Changing the number of chromosomes is a characteristic feature of aneuploidy, making it the correct answer. Point mutation, frameshift mutation, and missense mutation do not involve a change in the number of chromosomes and are focused on alterations at the nucleotide level within the DNA sequence.

2. Which neuromuscular system controls voluntary movement?

• A. Autonomic
• B. Somatic
• C. Sympathetic
• D. Parasympathetic

Correct answer: B

Rationale: The correct answer is B, Somatic. The somatic nervous system controls voluntary movements of skeletal muscles. It is responsible for carrying sensory and motor information to and from the central nervous system. Choices A, C, and D are incorrect. The autonomic nervous system (choice A) controls involuntary functions such as heart rate and digestion. The sympathetic (choice C) and parasympathetic (choice D) nervous systems are subdivisions of the autonomic nervous system and are responsible for the body's fight-or-flight response and rest-and-digest functions, respectively.

3. A researcher wants to investigate the relationship between family income and quality of medical care. Which statement provides the best reason to conduct this investigation?

• A. The researcher can identify affordable medical care to recommend to low-income families.
• B. The investigation can help identify individuals who are healthy so they can maintain their health.
• C. Results of this investigation may identify a group of people who do not receive quality medical care and could benefit from improved medical treatments.
• D. There is a valid reason to conduct this investigation.

Correct answer: C

Rationale: The correct answer is C because identifying a group of individuals who do not receive quality medical care can lead to targeted interventions to improve their access to better medical treatments. This investigation can help address disparities in healthcare and improve outcomes for those in need. Choice A is incorrect because the focus is on identifying those who lack quality medical care, not just affordable care. Choice B is incorrect as it misinterprets the purpose of the investigation, which is to improve medical care for those not receiving quality care, rather than maintaining the health of those already healthy. Choice D is too vague and does not provide a specific reason for conducting the investigation, unlike choice C which highlights the potential benefits of identifying individuals in need of improved medical treatments.

4. What is the primary function of the CRISPR-Cas9 system in gene editing?

• A. To amplify specific DNA sequences.
• B. To cut DNA at specific locations.
• C. To deliver genes into cells.
• D. To sequence entire genomes.

Correct answer: B

Rationale: The CRISPR-Cas9 system is a powerful tool used in gene editing to precisely target and cut DNA at specific locations within the genome. This system consists of a guide RNA that directs the Cas9 enzyme to the desired DNA sequence, where it creates a double-strand break. This break can then be repaired by the cell's natural DNA repair mechanisms, allowing for the introduction of specific genetic modifications. Options A, C, and D are incorrect as they do not accurately describe the primary function of the CRISPR-Cas9 system in gene editing. Amplifying DNA sequences, delivering genes into cells, and sequencing entire genomes are not the main functions of the CRISPR-Cas9 system, which is primarily focused on precise DNA cutting for targeted genetic modifications.

5. Which of the following bones is part of the axial skeleton?

• A. Femur
• B. Humerus
• C. Skull
• D. Pelvis

Correct answer: C

Rationale: The correct answer is C: Skull. The axial skeleton consists of bones along the body's central axis, including the skull, vertebral column, ribs, and sternum. Choices A, B, and D are incorrect because the femur, humerus, and pelvis are part of the appendicular skeleton, which comprises the bones of the limbs and girdles.

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