HESI A2
HESI A2 Practice Test Anatomy and Physiology
1. Which organelle is responsible for energy production in the cell?
- A. Nucleus
- B. Mitochondria
- C. Ribosomes
- D. Endoplasmic reticulum
Correct answer: B
Rationale: Mitochondria are the organelles responsible for energy production in the cell. They generate energy through cellular respiration, producing ATP, which is the primary energy currency of the cell. Known as the powerhouse of the cell, mitochondria play a vital role in meeting the energy demands of various cellular processes. The nucleus is responsible for storing genetic material, not energy production. Ribosomes are involved in protein synthesis, not energy production. The endoplasmic reticulum is involved in protein and lipid synthesis, as well as detoxification, but it is not primarily responsible for energy production.
2. Which organ system is primarily responsible for generating antibodies?
- A. The endocrine system
- B. The digestive system
- C. The lymphatic system
- D. The nervous system
Correct answer: C
Rationale: The correct answer is C: The lymphatic system. Antibodies are produced by specialized white blood cells called B-lymphocytes (or B cells) in response to foreign substances known as antigens. The lymphatic system includes lymph nodes, lymphatic vessels, tonsils, thymus, and spleen, which work together to produce and store antibodies to help the body fight off infections and diseases. Choice A, the endocrine system, is incorrect because it is responsible for hormone regulation, not antibody production. Choice B, the digestive system, is incorrect because its main function is to break down food and absorb nutrients, not produce antibodies. Choice D, the nervous system, is incorrect as it is responsible for transmitting signals throughout the body and coordinating body functions, not generating antibodies.
3. What is the main function of the large intestine?
- A. Absorption of nutrients
- B. Absorption of water
- C. Secretion of digestive enzymes
- D. Breaking down fats
Correct answer: B
Rationale: The main function of the large intestine is the absorption of water and electrolytes from indigestible food residues, helping to form solid waste (feces) for elimination. It mainly reabsorbs water and compacts the remaining material into feces, playing a crucial role in maintaining fluid balance in the body. Choices A, C, and D are incorrect because absorption of nutrients primarily occurs in the small intestine, secretion of digestive enzymes mainly occurs in the stomach and small intestine, and breaking down fats primarily occurs in the small intestine with the help of bile from the liver and enzymes.
4. What is the primary function of the hypothalamus?
- A. Regulates body balance and thermoregulation
- B. Controls hunger and thirst
- C. Regulates sleep and circadian rhythms
- D. Controls voluntary movements
Correct answer: A
Rationale: The primary function of the hypothalamus is to regulate body balance and thermoregulation. It plays a crucial role in maintaining overall body equilibrium by controlling functions such as body temperature and water balance. While the hypothalamus is also involved in hunger and thirst regulation, its main role is to ensure homeostasis by monitoring and adjusting body balance and temperature. Choices B, C, and D are incorrect because hunger and thirst regulation, sleep and circadian rhythm regulation, and control of voluntary movements are secondary functions of the hypothalamus compared to its primary role in maintaining body balance and thermoregulation.
5. Which gland produces the hormone melatonin?
- A. Pineal gland
- B. Thyroid gland
- C. Pituitary gland
- D. Adrenal gland
Correct answer: A
Rationale: The correct answer is the Pineal gland. The pineal gland is responsible for producing melatonin, a hormone that helps regulate the sleep-wake cycle. Melatonin secretion is influenced by light exposure. Higher levels are observed at night to promote sleep, while lower levels during the day encourage wakefulness. Choices B, C, and D are incorrect as they are not associated with the production of melatonin. The thyroid gland produces hormones like thyroxine and triiodothyronine, the pituitary gland controls various other glands, and the adrenal gland produces hormones like adrenaline and cortisol.
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