Nursing Elites

1. Which of the following structures acts like a funnel by delivering urine from the millions of collecting tubules to the ureters?

• A. The renal pelvis
• B. The renal cortex
• C. The renal medulla
• D. Bowman's capsule

Correct answer: A

Rationale: The correct answer is A: The renal pelvis. The renal pelvis serves as a reservoir for urine collected from the kidney's numerous collecting tubules, funneling it into the ureters for transport to the bladder. The renal cortex is the outer region of the kidney involved in filtration, while the renal medulla is the inner region responsible for concentrating urine. Bowman's capsule is part of the nephron and is involved in the initial filtration of blood in the kidney, not in funneling urine to the ureters.

2. What is the term for a genetic disorder caused by a mutation on the X chromosome?

• A. Autosomal dominant disorder
• B. Autosomal recessive disorder
• C. Sex-linked recessive disorder
• D. Sex-linked dominant disorder

Correct answer: C

Rationale: A genetic disorder caused by a mutation on the X chromosome is termed a sex-linked recessive disorder (Option C). This type of disorder is more commonly seen in males due to their single X chromosome, making them more vulnerable to X-linked mutations. Females have two X chromosomes, providing a protective effect against X-linked disorders.\n- Autosomal dominant disorders (Option A) result from a mutation in one copy of a gene on non-sex chromosomes (autosomes) and are not specifically related to the X chromosome.\n- Autosomal recessive disorders (Option B) occur due to mutations in both copies of a gene on autosomes, not on the X chromosome.\n- Sex-linked dominant disorders (Option D) are rare and lead to more severe symptoms in males as they only require one copy of the mutated gene on the X chromosome to express the disorder. However, this is not the term for a genetic disorder caused by an X chromosome mutation.

3. What is the 'lock-and-key' model?

• A. Protein folding
• B. Enzyme-substrate interaction
• C. Muscle contraction
• D. Blood clotting

Correct answer: B

Rationale: The 'lock-and-key' model describes the specificity of the interaction between enzymes and their substrates. In this model, the enzyme's active site acts like a lock that can only be opened by the specific substrate molecule, which serves as the key. This specific binding ensures that enzymes catalyze particular reactions and do not interact with other molecules indiscriminately. Protein folding (option A) is the process by which a protein attains its functional three-dimensional structure but is not directly related to the lock-and-key model. Muscle contraction (option C) and blood clotting (option D) are complex biological processes but are not directly associated with the lock-and-key model of enzyme-substrate interaction.

4. What is the first event to occur in a primary immune response?

• A. Macrophages phagocytose pathogens and present their antigens.
• B. Neutrophils aggregate and act as cytotoxic, nonspecific killers of pathogens.
• C. B lymphocytes make pathogen-specific antibodies.
• D. Helper T cells secrete interleukins to activate pathogen-fighting cells.

Correct answer: A

Rationale: The correct answer is A. The initial event in a primary immune response is the phagocytosis of pathogens by macrophages and the subsequent presentation of their antigens, which is crucial for initiating the adaptive immune response. Neutrophils (Choice B) are also involved in the innate immune response, but they typically respond after macrophages. B lymphocytes (Choice C) produce antibodies later in the adaptive immune response, and Helper T cells (Choice D) help in coordinating the immune response but are not the first cells to act in a primary immune response.

5. What is insulin, where is it produced, and what is its function?

• A. Produced in the liver, regulates fat storage
• B. Produced in the pancreas, regulates blood sugar
• C. Produced in the stomach, aids in digestion
• D. Produced in the kidneys, controls hydration

Correct answer: B

Rationale: Insulin is a hormone produced in the pancreas. Its primary function is to regulate blood sugar levels by facilitating the uptake of glucose by cells for energy. The other choices are incorrect as insulin is not produced in the liver (Choice A), stomach (Choice C), or kidneys (Choice D), and its function is not related to fat storage, digestion, or hydration. Therefore, the correct answer is B.

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