HESI A2
HESI A2 Practice Test Biology
1. Which of the following organelles is responsible for producing ATP in cells?
- A. Nucleus
- B. Mitochondrion
- C. Chloroplast
- D. Lysosome
Correct answer: B
Rationale: The correct answer is 'Mitochondrion.' Mitochondria are known as the powerhouse of the cell and are responsible for producing ATP, the energy currency of the cell. The nucleus is responsible for storing genetic material and controlling cell activities, not for ATP production. Chloroplasts are found in plant cells and are responsible for photosynthesis, not ATP production. Lysosomes are involved in digestion and waste removal, not ATP production.
2. What is the main function of the ribosomes in the cell?
- A. DNA Replication
- B. Protein Synthesis
- C. Lipid Breakdown
- D. Cell Division
Correct answer: B
Rationale: The correct answer is B: Protein Synthesis. Ribosomes are cellular organelles responsible for synthesizing proteins. This process is crucial for various cellular functions. Choice A, DNA Replication, is incorrect as ribosomes are not involved in this process. Choice C, Lipid Breakdown, is also incorrect as ribosomes do not play a role in lipid metabolism. Choice D, Cell Division, is incorrect as ribosomes are not directly involved in the process of cell division.
3. During protein synthesis, what process creates a complementary strand of RNA from a DNA template?
- A. Transcription
- B. Translation
- C. Transformation
- D. Replication
Correct answer: A
Rationale: The correct answer is 'Transcription.' During protein synthesis, transcription is the process that creates a complementary RNA strand from a DNA template. This process involves the synthesis of mRNA using DNA as a template. Choice B, 'Translation,' is incorrect as it is the process where the genetic code carried by mRNA is decoded to produce a specific polypeptide chain. Choice C, 'Transformation,' is not related to the synthesis of RNA from a DNA template. Choice D, 'Replication,' is the process of copying DNA to produce an identical DNA molecule, not RNA.
4. Which organelle is responsible for detoxifying harmful substances in the cell?
- A. Endoplasmic Reticulum
- B. Lysosomes
- C. Peroxisomes
- D. Golgi Apparatus
Correct answer: C
Rationale: The correct answer is C, Peroxisomes. Peroxisomes are responsible for detoxifying harmful substances in the cell by breaking down fatty acids and producing hydrogen peroxide. This process helps protect the cell from damage caused by toxic substances. Choice A, Endoplasmic Reticulum, is involved in protein and lipid synthesis, not detoxification. Choice B, Lysosomes, contain enzymes for digestion and waste removal, not primarily detoxification. Choice D, Golgi Apparatus, is responsible for modifying, sorting, and packaging proteins for secretion, not detoxification.
5. Which cells in the human body lack nuclei?
- A. Nerve cells
- B. Red blood cells
- C. Liver cells
- D. Connective tissue cells
Correct answer: B
Rationale: Red blood cells, also known as erythrocytes, lack nuclei in humans. This absence of a nucleus allows more space for hemoglobin, the protein responsible for carrying oxygen, making red blood cells efficient at their function of oxygen transport in the body. Nerve cells (Choice A), liver cells (Choice C), and connective tissue cells (Choice D) all possess nuclei as they require genetic material for their functions, such as cell signaling, protein synthesis, and structural support.
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