HESI A2
HESI A2 Anatomy and Physiology 2023
1. Which of the following is the largest organ in the human body?
- A. Liver
- B. Skin
- C. Brain
- D. Heart
Correct answer: B
Rationale: The skin is the largest organ in the human body. It serves as a protective barrier against the environment, regulates temperature, and provides sensory information. The liver, brain, and heart are vital organs, but they are not as extensive as the skin. The liver is primarily responsible for detoxification and metabolism. The brain is the control center of the body, coordinating various functions. The heart is a crucial organ that pumps blood throughout the body. However, in terms of size, the skin surpasses all of these organs.
2. Where are B-lymphocytes produced?
- A. Thymus
- B. Red bone marrow
- C. Lymph nodes
- D. Spleen
Correct answer: B
Rationale: B-lymphocytes are produced in the red bone marrow. The red bone marrow is the primary site for B-cell development, where they mature before entering the circulation. The thymus is responsible for T-lymphocyte maturation, not B-lymphocytes. Lymph nodes and spleen play roles in immune responses but are not the primary sites for B-lymphocyte production.
3. Which connective tissue type attaches muscles to bones?
- A. Ligaments
- B. Tendons
- C. Cartilage
- D. Fascia
Correct answer: B
Rationale: Tendons are the correct answer. They are strong connective tissues that connect muscles to bones, allowing movement when muscles contract. Ligaments connect bones to other bones, providing joint stability. Cartilage is a firm, flexible connective tissue present in joints and the outer ear. Fascia is a connective tissue that surrounds muscles, blood vessels, and nerves, offering support and protection. Therefore, the correct tissue type that connects muscles to bones is tendons.
4. What is the function of hemoglobin in red blood cells?
- A. To fight infections
- B. To transport oxygen
- C. To carry carbon dioxide
- D. To store oxygen
Correct answer: B
Rationale: The correct answer is B: 'To transport oxygen.' Hemoglobin in red blood cells plays a crucial role in transporting oxygen. It binds to oxygen in the lungs and carries it to the body's tissues and organs for cellular respiration. Choices A, C, and D are incorrect because hemoglobin's primary function is to bind and transport oxygen, not to fight infections, carry carbon dioxide, or store oxygen.
5. Which of the following hormones is responsible for regulating metabolism?
- A. Insulin
- B. Thyroxine
- C. Glucagon
- D. Cortisol
Correct answer: B
Rationale: Thyroxine, produced by the thyroid gland, is the hormone responsible for regulating metabolism. It plays a fundamental role in controlling the body's metabolic rate, affecting processes such as energy production and utilization. Thyroxine also influences growth and development in the body. Choice A, Insulin, is involved in regulating blood sugar levels and promoting the storage of glucose. While insulin has an impact on metabolism, it is not primarily responsible for regulating overall metabolic rate. Choice C, Glucagon, acts in opposition to insulin, stimulating the release of glucose from the liver to increase blood sugar levels. Glucagon primarily targets glucose regulation rather than overall metabolism. Choice D, Cortisol, is known as the stress hormone and plays a role in the body's response to stress, regulation of blood pressure, immune function, and anti-inflammatory actions. While cortisol can have some effects on metabolism during stress responses, it is not the primary hormone responsible for regulating overall metabolic rate.
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