Nursing Elites

1. Which of the following hormones is primarily responsible for regulating metabolism?

• A. Insulin
• B. Testosterone
• C. Adrenaline
• D. Thyroid hormone

Correct answer: D

Rationale: Thyroid hormone is the correct answer as it is primarily responsible for regulating metabolism. It plays a crucial role in controlling the body's metabolic rate, affecting how the body uses energy from food. Thyroid hormone levels can influence metabolism, energy production, and body weight regulation. Insulin, choice A, is involved in regulating blood sugar levels, not directly metabolism. Testosterone, choice B, is a sex hormone that primarily affects the development of male reproductive tissues. Adrenaline, choice C, is involved in the fight-or-flight response and not primarily responsible for regulating metabolism.

2. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

3. Which of the following correctly orders the layers of the epidermis from most superficial to deepest?

• A. S. spinosum, S. basale, S. corneum, S. granulosum, S. lucidum
• B. S. corneum, S. lucidum, S. granulosum, S. spinosum, S. basale
• C. S. corneum, S. spinosum, S. basale, S. granulosum, S. lucidum
• D. S. basale, S. spinosum, S. granulosum, S. lucidum, S. corneum

Correct answer: B

Rationale: The correct order of the layers of the epidermis from most superficial to deepest is: Stratum corneum, Stratum lucidum, Stratum granulosum, Stratum spinosum, Stratum basale. Choice B, 'S. corneum, S. lucidum, S. granulosum, S. spinosum, S. basale,' provides the accurate layering from the outermost to the innermost layer of the epidermis. Choice A is incorrect as it starts with Stratum spinosum, which is not the most superficial layer. Choice C is incorrect as it places Stratum spinosum before Stratum basale. Choice D is incorrect as it starts with Stratum basale, which is the deepest layer of the epidermis.

4. What is the main function of peroxisomes in the cell?

• A. To break down hydrogen peroxide
• B. To synthesize lipids and other cellular components
• C. To package and transport proteins
• D. To store genetic material

Correct answer: A

Rationale: Peroxisomes are membrane-bound organelles found in eukaryotic cells that contain enzymes involved in various metabolic processes. One of the main functions of peroxisomes is to break down hydrogen peroxide, a toxic byproduct of metabolism, into water and oxygen through the action of the enzyme catalase. This process helps protect the cell from oxidative damage caused by hydrogen peroxide. While peroxisomes are involved in other metabolic functions such as lipid metabolism and the synthesis of bile acids, their primary role is the breakdown of hydrogen peroxide. Choices B, C, and D are incorrect because peroxisomes are not primarily responsible for synthesizing lipids, packaging and transporting proteins, or storing genetic material within the cell.

5. Rusting of iron is an example of

• A. Endothermic reaction
• B. Exothermic reaction
• C. Single displacement reaction
• D. Photochemical reaction

Correct answer: A

Rationale: The rusting of iron is an endothermic reaction. This means that it absorbs heat from its surroundings to occur. Rusting involves the slow oxidation of iron in the presence of oxygen and water. As energy is absorbed during this process, it is classified as an endothermic reaction. Choice B, an exothermic reaction, releases heat instead of absorbing it, which is not the case in rusting. Choices C and D are unrelated to the process of rusting and do not involve the absorption of heat from the surroundings.

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