Nursing Elites

1. Which of the following antibodies can cross the placenta?

• A. IgA
• B. IgD
• C. IgG
• D. IgM

Correct answer: C

Rationale: The correct answer is IgG. IgG is the only antibody that can cross the placenta, providing passive immunity to the developing fetus. IgA, IgD, and IgM do not cross the placenta. IgA is mainly found in mucosal secretions, IgD is involved in the activation of B cells, and IgM is the first antibody produced in response to an infection, but it does not cross the placental barrier.

2. Which structure of the nervous system carries an action potential in the direction of a synapse?

• A. Cell body
• B. Axon
• C. Neuron
• D. Myelin

Correct answer: B

Rationale: The correct answer is the axon. The axon is the elongated, threadlike part of a neuron that carries nerve impulses away from the cell body towards other neurons or target cells, such as muscles or glands, in the direction of a synapse. Action potentials travel along the axon as electrical signals to communicate with neighboring cells. The cell body (choice A) contains the nucleus and organelles but does not transmit action potentials. Neuron (choice C) is a broad term that includes the entire nerve cell, not a specific structure. Myelin (choice D) is a fatty substance that surrounds and insulates axons, aiding in the conduction of nerve impulses, but it does not directly carry the action potential towards a synapse.

3. When a muscle shortens and generates force, this is called a:

• A. Contraction
• B. Relaxation
• C. Extension
• D. Atrophy

Correct answer: A

Rationale: When a muscle shortens and generates force, it is contracting. Contraction is the process by which muscle fibers develop tension and exert a pulling force on the bones they are attached to, resulting in movement. Relaxation refers to the phase when a muscle returns to its original length, allowing for rest or preparation for the next contraction. Extension, on the other hand, is the movement that increases the angle between body parts, moving them further apart. Atrophy is unrelated to muscle contraction and refers to the wasting away or decrease in size of muscle tissue due to disuse or disease. Therefore, the correct answer is 'Contraction.'

4. Which of the following is directly transcribed from DNA and represents the first step in protein synthesis?

• A. siRNA
• B. rRNA
• C. mRNA
• D. tRNA

Correct answer: C

Rationale: mRNA (messenger RNA) is directly transcribed from DNA in the nucleus during the process of transcription. It serves as a template for protein synthesis during translation in the cytoplasm. mRNA carries genetic information from the DNA to the ribosomes, where it determines the sequence of amino acids in a protein. Thus, mRNA represents the first step in protein synthesis as it carries the code from the DNA to be translated into a protein. Choice A, siRNA (small interfering RNA), is involved in post-transcriptional gene silencing and does not play a role in protein synthesis. Choice B, rRNA (ribosomal RNA), is a component of the ribosome and plays a structural and functional role in protein synthesis but is not directly transcribed from DNA. Choice D, tRNA (transfer RNA), is responsible for bringing amino acids to the ribosome during protein synthesis but is not directly transcribed from DNA.

5. What enzymes do lysosomes contain, leading to their nickname as the cell's 'suicide bags'?

• A. Hydrolytic enzymes
• B. Ligases (bonding enzymes)
• C. Transferases (molecule transfer)
• D. Oxidoreductases (redox reactions)

Correct answer: A

Rationale: Lysosomes are organelles filled with hydrolytic enzymes that break down proteins, nucleic acids, lipids, and carbohydrates. These enzymes aid in digesting cellular waste and foreign substances, hence the term 'suicide bags' due to their involvement in cell degradation and recycling. Ligases are enzymes that catalyze the joining of two large molecules by forming a new chemical bond, not present in lysosomes. Transferases are enzymes that catalyze the transfer of functional groups from one molecule to another, not found in lysosomes. Oxidoreductases are enzymes involved in oxidation-reduction reactions, which are not the primary function of lysosomes.

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