Nursing Elites

1. What is the role of the spindle apparatus in cell division?

• A. To separate sister chromatids
• B. To move chromosomes to opposite poles of the cell
• C. To form a new nuclear envelope around each daughter cell
• D. To synthesize new DNA

Correct answer: B

Rationale: The spindle apparatus, composed of microtubules, plays a crucial role in cell division (mitosis and meiosis) by ensuring proper chromosome separation and distribution to opposite poles of the cell. This segregation is vital for creating two genetically identical daughter cells in mitosis or four haploid daughter cells in meiosis. Choice A is incorrect because the separation of sister chromatids is specifically carried out by kinetochore fibers within the spindle apparatus. Choice C is inaccurate as the formation of a new nuclear envelope occurs post chromosome segregation. Choice D is incorrect as DNA synthesis does not occur within the spindle apparatus; it takes place during the S phase of the cell cycle.

2. Which feedback loop inhibits the stimulus or the deviation from homeostasis?

• A. Negative feedback loop
• B. Positive feedback loop
• C. Inhibitory feedback loop
• D. Stimulating feedback loop

Correct answer: A

Rationale: The correct answer is A: Negative feedback loop. Negative feedback loops work to inhibit the stimulus or reduce the deviation from a set point, maintaining homeostasis by counteracting any changes from the norm. In this case, the negative feedback loop acts to minimize any deviation from the body's internal balance, ensuring stability and optimal functioning. Choice B, a positive feedback loop, amplifies the stimulus or deviation, moving systems away from homeostasis. Choice C, an inhibitory feedback loop, is not a commonly recognized term in the context of feedback mechanisms. Choice D, a stimulating feedback loop, is not a standard term and does not accurately describe a feedback loop's role in maintaining homeostasis.

3. What enzymes do lysosomes contain, leading to their nickname as the cell's 'suicide bags'?

• A. Hydrolytic enzymes
• B. Ligases (bonding enzymes)
• C. Transferases (molecule transfer)
• D. Oxidoreductases (redox reactions)

Correct answer: A

Rationale: Lysosomes are organelles filled with hydrolytic enzymes that break down proteins, nucleic acids, lipids, and carbohydrates. These enzymes aid in digesting cellular waste and foreign substances, hence the term 'suicide bags' due to their involvement in cell degradation and recycling. Ligases are enzymes that catalyze the joining of two large molecules by forming a new chemical bond, not present in lysosomes. Transferases are enzymes that catalyze the transfer of functional groups from one molecule to another, not found in lysosomes. Oxidoreductases are enzymes involved in oxidation-reduction reactions, which are not the primary function of lysosomes.

4. Anya was paid by Company X to analyze dwindling honeybee populations in the Southwest. After measuring hive populations over several months, she noticed no patterns in the geographic distributions of the deaths after comparisons with local maps of interest. This supported her hypothesis, so she took samples of the honey and the bees from the hives and performed dozens of dissections to confirm her suspicions. Which of the following is the most likely hypothesis upon which this research was performed?

• A. Honeybees are being killed off, and their hives are destroyed by other extremely aggressive species of bees from the South.
• B. Honeybees are contracting parasites in large droves.
• C. Honeybees are so sensitive to certain pesticides that they die on contact.
• D. Honeybees die in larger numbers around cell phone towers.

Correct answer: B

Rationale: The most likely hypothesis based on the information provided is that honeybees are contracting parasites in large droves. Anya observed no geographic patterns in hive deaths and proceeded to analyze honey and bees for further investigation. This suggests that she suspected a widespread issue affecting multiple hives simultaneously, consistent with a scenario where honeybees are being infected by parasites in high numbers, leading to dwindling populations across different locations. The other choices can be eliminated because there is no mention of aggressive species of bees from the South, no evidence pointing to pesticide sensitivity as the cause, and no indication of a correlation with cell phone towers in the information provided.

5. What are the structural and functional units responsible for creating and transporting urine, located in the cortex of the kidney?

• A. Glomerulus
• B. Nephrons
• C. Loops of Henle
• D. Distal tubules

Correct answer: B

Rationale: The correct answer is 'Nephrons.' Nephrons are the structural and functional units of the kidneys responsible for creating and transporting urine. Each kidney contains thousands of nephrons located in the cortex and medulla. The nephron consists of the renal corpuscle, which includes the glomerulus, and the renal tubule, which consists of the proximal tubule, loops of Henle, and distal tubule. While the glomerulus, loops of Henle, and distal tubules are all parts of the nephron, the nephrons as a whole are specifically responsible for creating and transporting urine.

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