Nursing Elites

1. What is the role of the spindle apparatus in cell division?

• A. To separate sister chromatids
• B. To move chromosomes to opposite poles of the cell
• C. To form a new nuclear envelope around each daughter cell
• D. To synthesize new DNA

Correct answer: B

Rationale: The spindle apparatus, composed of microtubules, plays a crucial role in cell division (mitosis and meiosis) by ensuring proper chromosome separation and distribution to opposite poles of the cell. This segregation is vital for creating two genetically identical daughter cells in mitosis or four haploid daughter cells in meiosis. Choice A is incorrect because the separation of sister chromatids is specifically carried out by kinetochore fibers within the spindle apparatus. Choice C is inaccurate as the formation of a new nuclear envelope occurs post chromosome segregation. Choice D is incorrect as DNA synthesis does not occur within the spindle apparatus; it takes place during the S phase of the cell cycle.

2. Which of the following lists of joint types is in the correct order for increasing amounts of permitted motion (least mobile to most mobile)?

• A. Hinge, condyloid, saddle
• B. Saddle, hinge, condyloid
• C. Saddle, condyloid, hinge
• D. Hinge, saddle, condyloid

Correct answer: A

Rationale: The correct order of joint types, from least mobile to most mobile, is hinge, condyloid, saddle. A hinge joint allows movement in one plane (like a door hinge), a condyloid joint allows movement in two planes but not rotation (like the wrist), and a saddle joint allows movement in multiple directions (like the thumb). Choice A, 'Hinge, condyloid, saddle,' is the correct sequence as it accurately represents the order of increasing permitted motion in joints. Choices B, C, and D are incorrect because they do not follow the correct order of joint types from least mobile to most mobile as required by the question.

3. What is the term for the first exposure to a specific pathogen, leading to the development of an initial immune response?

• A. Primary immune response
• B. Secondary immune response
• C. Hypersensitivity reaction
• D. Immunological tolerance

Correct answer: A

Rationale: The correct answer is A: Primary immune response. The primary immune response refers to the initial encounter with a specific pathogen, which triggers the development of the first immune response by the immune system. This response involves activating immune cells like B cells and T cells to produce antibodies and memory cells specific to that pathogen. On the other hand, the secondary immune response occurs upon re-exposure to the same pathogen and is characterized by a faster, stronger, and more effective immune response due to the presence of memory cells from the primary response. Choices B, C, and D are incorrect. The secondary immune response is the response upon re-exposure, hypersensitivity reactions are exaggerated immune responses to antigens, and immunological tolerance is the immune system's ability to recognize and tolerate self-antigens without mounting an immune response.

4. Immunoglobulin G (IgG) is the most abundant antibody type, responsible for:

• A. Immediate allergic reactions
• B. Neutralizing toxins and viruses
• C. Activating other immune cells
• D. Protecting newborns from infections

Correct answer: B

Rationale: Immunoglobulin G (IgG) is indeed the most prevalent antibody type in the blood and tissue fluids. Its primary functions include neutralizing toxins and viruses, promoting phagocytosis, and activating the complement system. IgG plays a crucial role in long-term immunity and provides passive immunity to newborns by crossing the placenta, safeguarding them from infections. Immediate allergic reactions are mainly mediated by IgE, not IgG. While IgM is known for activating other immune cells, IgG focuses on other key functions within the immune response, such as neutralizing pathogens and enhancing phagocytosis. Therefore, the correct answer is B, as IgG is primarily involved in neutralizing toxins and viruses, rather than the other options presented.

5. What is the primary function of the cardiovascular system?

• A. To transport oxygen and nutrients
• B. To regulate blood pressure
• C. To digest food
• D. To filter waste products

Correct answer: A

Rationale: The primary function of the cardiovascular system is indeed to transport oxygen and nutrients to various tissues in the body. Choice B, 'To regulate blood pressure,' is incorrect as blood pressure regulation is one of the functions of the cardiovascular system but not its primary function. Choice C, 'To digest food,' is incorrect as digestion is primarily a function of the digestive system, not the cardiovascular system. Choice D, 'To filter waste products,' is incorrect as waste product filtration is primarily carried out by the kidneys and liver, not the cardiovascular system.

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