Nursing Elites

1. What is the process by which RNA molecules are modified after transcription but before translation?

• A. Replication
• B. Splicing
• C. Editing
• D. Packaging

Correct answer: B

Rationale: B) Splicing is the correct answer. Splicing is the process by which non-coding regions (introns) are removed from pre-mRNA, and the remaining coding regions (exons) are joined together to form mature mRNA. This modification occurs after transcription but before translation. A) Replication is incorrect as replication is the process by which DNA is copied to produce a new DNA molecule, not RNA modifications. C) Editing may involve RNA editing, but it is not commonly used to describe the modification of RNA molecules after transcription. D) Packaging is not the correct term as it refers to the condensation and organization of DNA into chromatin in eukaryotic cells, not the modification of RNA molecules.

2. Which of the following lists of joint types is in the correct order for increasing amounts of permitted motion (least mobile to most mobile)?

• A. Hinge, condyloid, saddle
• B. Saddle, hinge, condyloid
• C. Saddle, condyloid, hinge
• D. Hinge, saddle, condyloid

Correct answer: A

Rationale: The correct order of joint types, from least mobile to most mobile, is hinge, condyloid, saddle. A hinge joint allows movement in one plane (like a door hinge), a condyloid joint allows movement in two planes but not rotation (like the wrist), and a saddle joint allows movement in multiple directions (like the thumb). Choice A, 'Hinge, condyloid, saddle,' is the correct sequence as it accurately represents the order of increasing permitted motion in joints. Choices B, C, and D are incorrect because they do not follow the correct order of joint types from least mobile to most mobile as required by the question.

3. Diabetic nephropathy, a complication of diabetes, affects the:

• A. Ureters
• B. Bladder
• C. Urethra
• D. Nephrons

Correct answer: D

Rationale: Diabetic nephropathy, a complication of diabetes, affects the nephrons. Nephrons are the functional units of the kidneys responsible for filtering blood and producing urine. The high blood sugar levels associated with diabetes can damage the nephrons over time, leading to kidney dysfunction and, ultimately, kidney failure. Choices A, B, and C are incorrect because diabetic nephropathy primarily impacts the nephrons in the kidneys, not the ureters, bladder, or urethra.

4. What is the primary function of the CRISPR-Cas9 system in gene editing?

• A. To amplify specific DNA sequences.
• B. To cut DNA at specific locations.
• C. To deliver genes into cells.
• D. To sequence entire genomes.

Correct answer: B

Rationale: The CRISPR-Cas9 system is a powerful tool used in gene editing to precisely target and cut DNA at specific locations within the genome. This system consists of a guide RNA that directs the Cas9 enzyme to the desired DNA sequence, where it creates a double-strand break. This break can then be repaired by the cell's natural DNA repair mechanisms, allowing for the introduction of specific genetic modifications. Options A, C, and D are incorrect as they do not accurately describe the primary function of the CRISPR-Cas9 system in gene editing. Amplifying DNA sequences, delivering genes into cells, and sequencing entire genomes are not the main functions of the CRISPR-Cas9 system, which is primarily focused on precise DNA cutting for targeted genetic modifications.

5. Which of the following is NOT a recommended method for preventing healthcare-associated infections (HAIs)?

• A. Handwashing with soap and water
• B. Proper use of personal protective equipment (PPE)
• C. Disinfecting and reusing sterile medical devices
• D. Using single-use sterile medical devices

Correct answer: C

Rationale: Disinfecting and reusing sterile medical devices is not a recommended method for preventing healthcare-associated infections (HAIs). Reusing sterile medical devices can increase the risk of infections due to inadequate sterilization or potential damage to the devices during the reprocessing process. Proper sterilization and disposal of single-use medical devices are essential in preventing the transmission of infections in healthcare settings. A) Handwashing with soap and water is a crucial method for preventing HAIs as it helps to remove and reduce the number of pathogens on the hands of healthcare workers, preventing the spread of infections. B) Proper use of personal protective equipment (PPE) such as gloves, gowns, masks, and eye protection is important in preventing the transmission of infections between patients and healthcare workers. C) Disinfecting and reusing sterile medical devices is not a recommended practice as it can lead to the transmission of infections if the devices are not adequately sterilized. Using single-use sterile medical devices helps to ensure that each patient receives a sterile device, reducing the risk of infections.

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