HESI A2
HESI A2 Anatomy and Physiology 2023
1. What is the function of the pituitary gland?
- A. Regulating metabolism
- B. Producing bile
- C. Filtering blood
- D. Controlling muscle movement
Correct answer: A
Rationale: The pituitary gland, known as the 'master gland,' plays a crucial role in regulating various physiological processes by secreting hormones that control other endocrine glands. This includes the regulation of metabolism, growth, reproduction, stress response, and more. Therefore, the correct function of the pituitary gland is regulating metabolism, making choice A the correct answer. Choices B, C, and D are incorrect as the pituitary gland is not involved in producing bile, filtering blood, or controlling muscle movement.
2. Which cellular structure is responsible for protein synthesis?
- A. Nucleus
- B. Ribosome
- C. Endoplasmic reticulum
- D. Golgi apparatus
Correct answer: B
Rationale: The correct answer is B: Ribosome. Ribosomes, the cellular structures located in the cytoplasm or on the endoplasmic reticulum, are responsible for protein synthesis in the cell. They are the sites where mRNA is translated into proteins, making them essential for the synthesis of proteins in all living cells. The other choices, such as the nucleus (choice A), endoplasmic reticulum (choice C), and Golgi apparatus (choice D), are not directly involved in protein synthesis. The nucleus contains DNA and is responsible for housing the genetic material, the endoplasmic reticulum is involved in protein folding and transport, and the Golgi apparatus is responsible for modifying, sorting, and packaging proteins.
3. Which of the following is not part of the body’s secondary defense system?
- A. Macrophages
- B. Leukocytes
- C. T cells
- D. Cilia
Correct answer: D
Rationale: Cilia are not part of the body's secondary defense system. They are hair-like structures primarily involved in movement and transporting substances across cell surfaces, such as in the respiratory tract for debris and pathogen removal. However, cilia do not play a direct role in the immune response mechanisms characteristic of the body's secondary defense system. Macrophages, leukocytes, and T cells are immune cells that actively participate in the secondary defense system by targeting and eliminating pathogens.
4. When are gallstones most problematic?
- A. When they block a duct
- B. When they contain cholesterol
- C. When they contain bilirubin
- D. When they begin to dissolve
Correct answer: A
Rationale: Gallstones become most problematic when they block a duct, such as the bile duct or cystic duct. This blockage can lead to various complications, including inflammation, infection, and even damage to the gallbladder or liver. In severe cases, a blocked duct can cause intense pain, jaundice, and other serious symptoms that require medical intervention. Choices B, C, and D are incorrect because the presence of cholesterol or bilirubin in gallstones or the process of dissolution do not necessarily indicate when gallstones become most problematic. The critical issue arises when the stones obstruct a duct, leading to complications.
5. Which hormone initiates the preparation of the endometrium of the uterus for pregnancy?
- A. FSH
- B. Estrogen
- C. LH
- D. Progesterone
Correct answer: D
Rationale: Progesterone initiates the preparation of the endometrium of the uterus for pregnancy. It promotes the growth of blood vessels and glands in the endometrial lining, making it conducive for implantation and supporting early pregnancy. While estrogen helps in thickening the endometrium, it is progesterone that plays a crucial role in preparing it for pregnancy. FSH (Follicle-stimulating hormone) is involved in stimulating ovarian follicles, not directly in preparing the endometrium. LH (Luteinizing hormone) triggers ovulation but does not primarily prepare the endometrium for pregnancy.
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