HESI A2
HESI A2 Biology 2024
1. What happens to messenger RNA when it reaches the cytoplasm?
- A. It attaches to a ribosome.
- B. It unzips, exposing nitrogen bases.
- C. It pairs with the DNA bases.
- D. It pulls free of the DNA strand.
Correct answer: A
Rationale: Messenger RNA (mRNA) carries genetic information from the DNA in the nucleus to the ribosomes in the cytoplasm. When mRNA reaches the cytoplasm, it attaches to a ribosome. The ribosome functions as the site for protein synthesis through translation, where the genetic code carried by mRNA is read and translated into a specific sequence of amino acids. Choices B, C, and D are incorrect because mRNA does not unzip, expose nitrogen bases, pair with DNA bases, or pull free of the DNA strand in the cytoplasm. The primary function of mRNA in the cytoplasm is to serve as a template for protein synthesis by binding to ribosomes.
2. What is the primary function of the endoplasmic reticulum in a cell?
- A. Energy production
- B. Protein synthesis
- C. Waste removal
- D. Transport of materials
Correct answer: D
Rationale: The endoplasmic reticulum's primary function is the transport of materials within the cell. It acts as a network of membranes to assist in the transportation of proteins and other substances throughout the cell. Choice A, 'Energy production,' is incorrect because the endoplasmic reticulum is not directly involved in energy production. Choice B, 'Protein synthesis,' is incorrect as protein synthesis mainly occurs in ribosomes, although the endoplasmic reticulum is involved in modifying and transporting proteins. Choice C, 'Waste removal,' is also incorrect as waste removal is primarily handled by other organelles like lysosomes and peroxisomes.
3. How should a researcher test the hypothesis that radiation from cell phones is significant enough to raise the temperature of water in a test tube?
- A. Dial a cell phone that rests beside a test tube of water, let it ring for two minutes, and record the temperature of the water before and after the two-minute interval.
- B. Dial a cell phone that rests beside a test tube of water; let it ring for two, three, and four minutes; and record the temperature of the water before and after each interval.
- C. Use three different brands of cell phone; dial each as it rests beside its own test tube of water, let it ring for two minutes, and record the temperature of the water before and after the two-minute interval.
- D. Use three different brands of cell phone, dial each and let one ring for two minutes, one for three minutes, and one for four minutes; record the temperature of the water before and after each interval.
Correct answer: A
Rationale: To test the hypothesis that radiation from cell phones raises the temperature of water in a test tube, the most appropriate method is to dial a cell phone next to a test tube of water, let it ring for a consistent two-minute interval, and record the temperature before and after. Choice A is correct because it provides a controlled approach to isolate the impact of the phone's radiation on the water temperature. Choices B, C, and D introduce additional variables that could confound the results. Choice B varies the duration of exposure, making it difficult to attribute temperature changes specifically to the radiation. Choice C introduces the factor of different cell phone brands, which could introduce variability not related to radiation. Choice D also varies exposure times and introduces the factor of multiple phone brands, making it harder to determine the direct impact of cell phone radiation on water temperature. Therefore, choice A is the most suitable option for this experiment.
4. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
5. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
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