HESI A2
HESI A2 Biology 2024
1. What happens to messenger RNA when it reaches the cytoplasm?
- A. It attaches to a ribosome.
- B. It unzips, exposing nitrogen bases.
- C. It pairs with the DNA bases.
- D. It pulls free of the DNA strand.
Correct answer: A
Rationale: Messenger RNA (mRNA) carries genetic information from the DNA in the nucleus to the ribosomes in the cytoplasm. When mRNA reaches the cytoplasm, it attaches to a ribosome. The ribosome functions as the site for protein synthesis through translation, where the genetic code carried by mRNA is read and translated into a specific sequence of amino acids. Choices B, C, and D are incorrect because mRNA does not unzip, expose nitrogen bases, pair with DNA bases, or pull free of the DNA strand in the cytoplasm. The primary function of mRNA in the cytoplasm is to serve as a template for protein synthesis by binding to ribosomes.
2. Which molecules contain only carbon, hydrogen, and oxygen?
- A. Lipids and proteins
- B. Carbohydrates and lipids
- C. Proteins and carbohydrates
- D. Nucleic acids and proteins
Correct answer: B
Rationale: Carbohydrates and lipids are the molecules that contain only carbon, hydrogen, and oxygen. Carbohydrates such as sugars and starches are made up of carbon, hydrogen, and oxygen in a ratio of 1:2:1, while lipids such as fats and oils are composed of carbon, hydrogen, and oxygen as well. Lipids typically contain more carbon and hydrogen atoms compared to oxygen atoms. Proteins contain nitrogen in addition to carbon, hydrogen, and oxygen, while nucleic acids contain phosphorus in addition to carbon, hydrogen, and oxygen. Therefore, choices A, C, and D are incorrect as they include molecules that contain elements other than carbon, hydrogen, and oxygen.
3. Which statement is true of enzymes?
- A. They are made from lipids.
- B. They are made from proteins.
- C. They form double chains of DNA.
- D. They bind with catalysts.
Correct answer: B
Rationale: The correct answer is B: Enzymes are made from proteins. Enzymes are biological molecules that act as catalysts to speed up chemical reactions in living organisms. While the majority of enzymes are proteins, a few are made from RNA. The statement that enzymes are made from lipids (choice A) is incorrect. Enzymes do not form double chains of DNA (choice C) as their primary function is not related to DNA structure. Additionally, enzymes themselves do not bind with catalysts (choice D); instead, they act as catalysts to facilitate reactions.
4. The fur color in a population of dogs is controlled by two alleles: black (B) and tan (b). The black allele exhibits complete dominance. If the phenotype of the dog is tan fur, what is its genotype?
- A. BB
- B. Bb
- C. bb
- D. Not enough information
Correct answer: C
Rationale: The correct answer is C: "bb." Since tan fur is the recessive trait controlled by the allele 'b,' the only possible genotype for a dog with tan fur is 'bb.' If a dog had the genotype 'BB' or 'Bb,' the dominant trait (black fur) would be expressed, not tan fur. Choice D, 'Not enough information,' is incorrect because based on the information provided, we can deduce the genotype of a dog with tan fur.
5. The two catabolic pathways that lead to cellular energy production are:
- A. fermentation and protein synthesis
- B. cellular respiration and glycolysis
- C. fermentation and glycolysis
- D. cellular respiration and fermentation
Correct answer: D
Rationale: The correct answer is D: cellular respiration and fermentation. Cellular respiration involves the breakdown of glucose in the presence of oxygen to produce ATP, which is the primary source of energy for cells. Fermentation, on the other hand, occurs in the absence of oxygen and produces ATP through glycolysis followed by specific fermentation pathways. Choices A, B, and C are incorrect. Protein synthesis is a biosynthetic process, not a catabolic pathway for energy production. Glycolysis is a common step in both cellular respiration and fermentation, so it is not a pair of distinct catabolic pathways. Therefore, the most accurate pairing of catabolic pathways for cellular energy production is cellular respiration and fermentation.
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