what happens to messenger rna as it reaches the cytoplasm
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HESI A2

HESI A2 Biology 2024

1. What happens to messenger RNA when it reaches the cytoplasm?

Correct answer: A

Rationale: Messenger RNA (mRNA) carries genetic information from the DNA in the nucleus to the ribosomes in the cytoplasm. When mRNA reaches the cytoplasm, it attaches to a ribosome. The ribosome functions as the site for protein synthesis through translation, where the genetic code carried by mRNA is read and translated into a specific sequence of amino acids. Choices B, C, and D are incorrect because mRNA does not unzip, expose nitrogen bases, pair with DNA bases, or pull free of the DNA strand in the cytoplasm. The primary function of mRNA in the cytoplasm is to serve as a template for protein synthesis by binding to ribosomes.

2. If both parents have polydactylism, what percentage of their offspring is predicted to manifest the anomaly?

Correct answer: B

Rationale: When both parents have polydactylism, they each possess at least one dominant allele for polydactylism. Through a Punnett square analysis, it can be determined that 50% of their offspring will inherit the dominant allele from both parents. This results in a 100% chance of manifesting the anomaly (2 out of 4 possibilities). Therefore, 50% of the offspring are predicted to manifest the anomaly. Choices A, C, and D are incorrect as they do not align with the principles of Mendelian genetics and Punnett square analysis.

3. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

4. ___________ is a symbiotic relationship in which one organism benefits and the other is not affected.

Correct answer: C

Rationale: The correct answer is 'Commensalism.' In commensalism, one organism benefits from the relationship while the other is neither helped nor harmed. This type of symbiotic relationship is characterized by one organism deriving a benefit, such as food or shelter, without impacting the other organism in any significant way. Choice A, 'Mutualism,' is a symbiotic relationship in which both organisms benefit. Choice B, 'Parasitism,' is a symbiotic relationship in which one organism benefits at the expense of the other. Choice D, 'Competition,' refers to a relationship in which organisms compete for limited resources, with both being affected in terms of access to resources.

5. How does an enzyme work on a chemical reaction that occurs in a substrate?

Correct answer: B

Rationale: Enzymes are biological catalysts that facilitate chemical reactions by lowering the activation energy required for the reaction to occur. This allows the reaction to proceed more quickly and efficiently. Enzymes do not change the overall outcome of the reaction, but they significantly increase the rate at which it takes place. Therefore, choice B, 'An enzyme speeds up the chemical reaction,' is the correct answer. Choices A, C, and D are incorrect because enzymes do not slow down, have no effect, or stop chemical reactions; instead, they accelerate the process by lowering the activation energy.

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