Nursing Elites

1. What is the microscopic functional unit of the kidney responsible for filtering blood?

• A. Ureter
• B. Nephron
• C. Renal pelvis
• D. Bladder

Correct answer: B

Rationale: The nephron is the correct answer as it is the microscopic functional unit of the kidney responsible for filtering blood. It is composed of a renal corpuscle (glomerulus and Bowman's capsule) and a renal tubule. The other options, such as (A) Ureter, (C) Renal pelvis, and (D) Bladder, do not play a role in filtering blood within the kidney. The ureter is a tube that carries urine from the kidney to the bladder. The renal pelvis is a part of the kidney where urine collects before entering the ureter. The bladder is an organ that stores urine until it is excreted from the body.

2. Which type of joint connects the bones of the skull?

• A. Synovial
• B. Fibrous
• C. Cartilaginous
• D. Ball-and-socket

Correct answer: B

Rationale: Fibrous joints connect the bones of the skull. These joints are immovable or provide very limited movement, providing stability and protection to the brain. Synovial joints (Choice A) are found in the limbs and allow for a wide range of movements. Cartilaginous joints (Choice C) are connected by cartilage and allow limited movement. Ball-and-socket joints (Choice D) allow for a wide range of motion, such as the hip and shoulder joints, but they do not connect the bones of the skull.

3. What type of genetic testing can reveal an individual's susceptibility to certain diseases?

• A. Karyotyping
• B. Pharmacogenomics
• C. Paternity testing
• D. Microarray analysis

Correct answer: D

Rationale: A) Karyotyping is a genetic test that examines an individual's chromosomes to detect abnormalities such as extra or missing chromosomes. It is not typically used to reveal an individual's susceptibility to certain diseases. B) Pharmacogenomics is the study of how genes affect a person's response to drugs. It focuses on how genetic variations can influence drug response, rather than susceptibility to diseases. C) Paternity testing is a genetic test used to determine the biological relationship between a child and an alleged father. It is not used to reveal an individual's susceptibility to diseases. D) Microarray analysis is a type of genetic testing that can reveal an individual's susceptibility to certain diseases by analyzing variations in their DNA. It can identify genetic markers associated with increased risk for specific conditions, allowing for personalized risk assessment and preventive measures.

4. What is the term for a genetic disorder caused by a mutation on the X chromosome?

• A. Autosomal dominant disorder
• B. Autosomal recessive disorder
• C. Sex-linked recessive disorder
• D. Sex-linked dominant disorder

Correct answer: C

Rationale: A genetic disorder caused by a mutation on the X chromosome is termed a sex-linked recessive disorder (Option C). This type of disorder is more commonly seen in males due to their single X chromosome, making them more vulnerable to X-linked mutations. Females have two X chromosomes, providing a protective effect against X-linked disorders.\n- Autosomal dominant disorders (Option A) result from a mutation in one copy of a gene on non-sex chromosomes (autosomes) and are not specifically related to the X chromosome.\n- Autosomal recessive disorders (Option B) occur due to mutations in both copies of a gene on autosomes, not on the X chromosome.\n- Sex-linked dominant disorders (Option D) are rare and lead to more severe symptoms in males as they only require one copy of the mutated gene on the X chromosome to express the disorder. However, this is not the term for a genetic disorder caused by an X chromosome mutation.

5. Endotoxins are toxic substances released by:

• A. Viruses
• B. Bacteria (gram-positive)
• C. Bacteria (gram-negative)
• D. Parasites

Correct answer: C

Rationale: Endotoxins are toxic substances that are part of the outer membrane of the cell wall of gram-negative bacteria. These toxins are released when the bacteria are destroyed or during bacterial growth. Endotoxins can cause a variety of harmful effects in the host, including fever, inflammation, and septic shock. Viruses do not produce endotoxins; they are typically associated with producing viral proteins that can be toxic to host cells. Gram-positive bacteria produce exotoxins, which are different from endotoxins found in gram-negative bacteria. Parasites, though capable of causing diseases, are not typically associated with the production of endotoxins.

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