HESI A2
Biology HESI A2 Practice Test
1. Phenotype refers to the _ of an individual.
- A. Genetic makeup
- B. Actual physical appearance
- C. Recessive alleles
- D. None of the above
Correct answer: B
Rationale: Phenotype refers to the actual physical appearance and characteristics of an individual, which are determined by the interaction of both genetic makeup (genotype) and environmental factors. It includes visible traits such as height, eye color, and hair type. Choice A, genetic makeup, refers to the genotype, which is the genetic constitution of an organism. Choice C, recessive alleles, is a specific type of gene variant and does not encompass the entire concept of phenotype. Choice D, none of the above, is incorrect as phenotype does refer to the actual physical appearance of an individual.
2. 72 chromosomes undergo meiosis. How many chromosomes will be in each gamete?
- A. 18
- B. 36
- C. 72
- D. 144
Correct answer: A
Rationale: During meiosis, the number of chromosomes is halved in each gamete. Since 72 chromosomes undergo meiosis, each gamete will contain half of that number, which is 36 chromosomes. Therefore, the correct answer is 18 chromosomes in each gamete. Choice B (36 chromosomes) is incorrect because it represents the total number of chromosomes that undergo meiosis, not the number in each gamete. Choice C (72 chromosomes) is incorrect as it represents the initial number of chromosomes, not the number in each gamete after meiosis. Choice D (144 chromosomes) is incorrect as it doubles the initial number of chromosomes, which is not the outcome of meiosis.
3. In a strand of DNA, you would expect to see adenine paired with ___________.
- A. cytosine
- B. uracil
- C. thymine
- D. guanine
Correct answer: C
Rationale: In a strand of DNA, adenine always pairs with thymine through two hydrogen bonds. This pairing is a fundamental aspect of DNA structure, where adenine and thymine complement each other in the double helix. Choice A (cytosine) is incorrect because adenine does not pair with cytosine in DNA. Choice B (uracil) is incorrect as uracil is found in RNA, not DNA. Choice D (guanine) is incorrect as guanine pairs with cytosine, not adenine, in DNA.
4. Patient A, who weighs 68 kilograms, steps onto a scale 20 times. The scale consistently weighs Patient A as 75 kilograms. What is true of the measurement?
- A. It is valid, but not reliable.
- B. It is reliable, but not valid.
- C. It is both valid and reliable.
- D. It is neither reliable nor valid.
Correct answer: B
Rationale: The correct answer is B: 'It is reliable, but not valid.' The measurement is reliable because it consistently provides the same result (75 kg). However, it is not valid because it does not accurately reflect the true weight of Patient A (68 kg). Choice A is incorrect because if the scale consistently shows the same weight (75 kg), it is reliable. Choice C is incorrect because although the scale is consistent, the measurement does not reflect the true weight, making it not valid. Choice D is incorrect as the measurement is reliable but lacks validity.
5. How many pairs of chromosomes do all humans have?
- A. 24 pairs
- B. 23 pairs
- C. 22 pairs
- D. 20 pairs
Correct answer: B
Rationale: All humans have 23 pairs of chromosomes, totaling 46 chromosomes. Choice A is incorrect because humans do not have 24 pairs. Choice C is incorrect as humans have 23 pairs, not 22 pairs. Choice D is incorrect as humans have 23 pairs of chromosomes, not 20 pairs.
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