in what way does spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints

ATI TEAS 7

TEAS 7 science practice questions

1. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

2. How do DNA and RNA function together as part of the human genome?

A. DNA carries genetic information from RNA to the cell cytoplasm.
B. RNA carries genetic information from DNA to the cell cytoplasm.
C. DNA and RNA carry genetic information from the cell nucleus to the cytoplasm.
D. DNA and RNA do not interact within the cell.

Correct answer: B

Rationale: The correct answer is B. RNA acts as a messenger carrying genetic instructions from the DNA in the nucleus to the cytoplasm, where proteins are synthesized. This process is known as transcription and translation, where DNA provides the blueprint for protein synthesis, and RNA delivers this information to the cellular machinery in the cytoplasm. Choice A is incorrect as it inaccurately states that DNA carries genetic information from RNA, which is the opposite of the actual flow of information. Choice C is incorrect as it suggests that both DNA and RNA together carry genetic information from the nucleus to the cytoplasm, which is not accurate. Choice D is incorrect as DNA and RNA do interact within the cell, playing crucial roles in genetic information processing and protein synthesis.

3. If every child in a certain family suffers from autism, what possible conclusion can be drawn about autism?

A. Autism may be lethal.
B. Autism may be genetic.
C. Autism is related to traditional nuclear family structures.
D. No conclusion can be drawn based on this evidence.

Correct answer: B

Rationale: The possible conclusion that can be drawn from every child in a certain family suffering from autism is that autism may be genetic. The fact that every child in the family has autism suggests a strong genetic influence on the condition within this particular family. This does not necessarily mean that autism is solely genetic in all cases, but in this specific family, the pattern of all children being affected points towards a genetic connection. Choice A is incorrect as the information provided does not suggest that autism is lethal. Choice C is incorrect as there is no evidence to support a relationship between autism and traditional nuclear family structures. Choice D is incorrect because a conclusion can be drawn from the given evidence, indicating a potential genetic link within this specific family.

4. Which division of the autonomic nervous system is responsible for the 'rest and digest' response, promoting relaxation and conservation of energy?

A. Sympathetic nervous system
B. Parasympathetic nervous system
C. Somatic nervous system
D. Central nervous system

Correct answer: B

Rationale: The correct answer is B: Parasympathetic nervous system. The parasympathetic nervous system is responsible for the 'rest and digest' response, promoting relaxation, conserving energy, and facilitating activities like digestion and lowering heart rate. The sympathetic nervous system, which is not the correct answer, triggers the 'fight or flight' response, preparing the body for stressful situations by increasing heart rate, dilating airways, and releasing adrenaline. The somatic nervous system (choice C) controls voluntary movements, not the autonomic functions related to 'rest and digest.' The central nervous system (choice D) includes the brain and spinal cord and is not specifically involved in the autonomic regulation of bodily functions like the 'rest and digest' response.

5. What is the approximate composition of blood?

A. 45% plasma, 55% formed elements
B. 55% plasma, 45% formed elements
C. 55% water, 45% blood cells
D. 45% water, 55% plasma

Correct answer: B

Rationale: Blood is composed of approximately 55% plasma (mostly water with proteins, electrolytes, and nutrients) and 45% formed elements (red blood cells, white blood cells, and platelets). Choice B is the correct answer. Choice A is incorrect as it reverses the percentages. Choice C is incorrect because it incorrectly states that blood cells make up 45% of blood, while they are part of the formed elements along with platelets. Choice D is incorrect as it suggests that water makes up 45% of blood, which is not accurate.