in what way does spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints

ATI TEAS 7

TEAS 7 science practice questions

1. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

2. Which of the following best describes the relationship among density, volume, and mass?

A. As volume increases, density decreases.
B. As volume decreases, density increases.
C. An object's mass does not affect its density.
D. As volume decreases, mass increases.

Correct answer: B

Rationale: The correct answer is B: 'As volume decreases, density increases.' This is because density is defined as mass divided by volume. When volume decreases and mass remains constant, the ratio of mass to volume increases, leading to higher density. Choice A is incorrect because as volume increases, density typically remains constant or increases due to the mass also increasing. Choice C is incorrect because an object's density is directly influenced by its mass. Choice D is incorrect as decreasing volume does not lead to an increase in mass.

3. What is the normal (complete) flow of blood through the heart?

A. Right atrium → lungs → left atrium → body
B. Left atrium → left ventricle → body → right atrium
C. Right atrium → right ventricle → lungs → left atrium → left ventricle → aorta → body
D. Right ventricle → left ventricle → body

Correct answer: C

Rationale: The correct flow of blood through the heart starts with the right atrium receiving deoxygenated blood from the body, followed by the right ventricle pumping blood to the lungs for oxygenation. Oxygenated blood then returns to the heart through the left atrium, then passes to the left ventricle which pumps it out to the body through the aorta. This flow ensures that blood is properly oxygenated before circulating through the body. Choice A is incorrect as the blood does not go directly from the left atrium to the body, skipping the left ventricle. Choice B is incorrect as it does not follow the correct flow sequence in the heart. Choice D is incorrect as it does not include the full pathway of blood through the heart.

4. Which type of blood cell is responsible for carrying oxygen?

A. White blood cell
B. Red blood cell
C. Platelet
D. Plasma

Correct answer: B

Rationale: The correct answer is B: Red blood cell. Red blood cells, also known as erythrocytes, are responsible for carrying oxygen from the lungs to the body's tissues. They contain hemoglobin, a protein that binds to oxygen and transports it throughout the body. White blood cells (Choice A) are part of the immune system and help fight infections, not involved in carrying oxygen. Platelets (Choice C) are responsible for blood clotting, not oxygen transport. Plasma (Choice D) is the liquid component of blood that carries various substances like nutrients and waste products, but it does not directly carry oxygen.

5. What is the primary function of nephrons?

A. Store urine
B. Filter blood and remove waste products
C. Produce hormones
D. Control blood pressure

Correct answer: B

Rationale: Nephrons are the functional units of the kidneys responsible for filtering blood to remove waste products, excess ions, and water. This process leads to the formation of urine, aiding in maintaining the body's fluid and electrolyte balance. The primary function of nephrons is not to store urine but to filter blood and eliminate waste products. Choice C, 'Produce hormones,' is incorrect as nephrons primarily focus on filtration rather than hormone production. Choice D, 'Control blood pressure,' is also incorrect as while the kidneys do play a role in regulating blood pressure, it is not the primary function of nephrons within the kidneys.