Nursing Elites

1. Where does glycolysis occur within the cell?

• A. Cytosol
• B. Nucleus
• C. Mitochondria
• D. Endoplasmic reticulum

Correct answer: A

Rationale: Glycolysis occurs in the cytosol, the liquid component of the cytoplasm, not in the nucleus, mitochondria, or endoplasmic reticulum. It is the initial step in cellular respiration and involves the breakdown of glucose into pyruvic acid. The process takes place in the cytosol as it does not require membrane-bound organelles like the mitochondria or endoplasmic reticulum for its completion.

2. Which type of capillary is the most common and least permeable?

• A. Fenestrated capillaries
• B. Sinusoidal capillaries
• C. Continuous capillaries
• D. Discontinuous capillaries

Correct answer: C

Rationale: The correct answer is C, continuous capillaries. Continuous capillaries are the most common and least permeable type of capillary. They are found in most tissues, including muscle and the nervous system. Continuous capillaries have a continuous endothelium without fenestrations or large gaps, which limits the movement of substances across their walls. Choice A, fenestrated capillaries, have pores (fenestrations) in their endothelial cells, making them more permeable than continuous capillaries. Choice B, sinusoidal capillaries, have a discontinuous endothelium with large gaps between cells, making them more permeable and allowing larger molecules and cells to pass through compared to continuous capillaries. Choice D, discontinuous capillaries, are similar to sinusoidal capillaries with a discontinuous endothelium, allowing for enhanced permeability compared to continuous capillaries.

3. Not all cells in the pancreas secrete insulin because of the hormone somatostatin, which inhibits the release of insulin by all cells. What type of intercellular chemical signal does this illustrate?

• A. Autocrine
• B. Neuromodulator
• C. Paracrine
• D. Pheromone

Correct answer: C

Rationale: The correct answer is C: Paracrine. Somatostatin acts in a paracrine manner by inhibiting the release of insulin from nearby cells within the pancreas. Paracrine signaling involves the secretion of signals that act on neighboring cells, as seen in this scenario where somatostatin affects nearby pancreatic cells without entering the bloodstream or affecting distant cells. Autocrine signaling involves cells responding to substances they themselves release, which is not the case here. Neuromodulators are chemicals that modulate the activity of neurons, not directly related to this scenario. Pheromones are chemicals released into the environment to communicate with individuals of the same species, not relevant to the signaling within the pancreas.

4. How do vaccines work?

• A. By directly killing pathogens
• B. By introducing weakened or inactive versions of pathogens to trigger an immune response
• C. By stimulating the immediate production of specific antibodies
• D. None of the above

Correct answer: B

Rationale: Vaccines work by introducing weakened or inactive versions of pathogens to trigger an immune response in the body. This exposure helps the immune system recognize and remember the pathogen, enabling a faster and more effective response upon future exposure. Vaccines do not directly kill pathogens but prepare the immune system for a potential encounter, enhancing protection. They also do not stimulate the immediate production of specific antibodies as the immune response takes time to develop upon vaccination. Choice A is incorrect because vaccines do not kill pathogens directly; they prime the immune system to recognize and respond to them. Choice C is incorrect because while vaccines lead to the production of specific antibodies, it is not immediate, as it takes time for the immune response to develop and produce these antibodies.

5. Which of the following describes an experiment?

• A. The final math grades for a group of students passing through each year of elementary school are examined.
• B. The health trends of smokers in a small random sample are examined.
• C. Citizens in a local community are surveyed to determine concerns related to the next election.
• D. The effects of a new drug are tested on a group of participants.

Correct answer: D

Rationale: Option D describes an experiment because it involves testing the effects of a new drug on a group of participants. In an experiment, researchers intentionally manipulate an independent variable (in this case, the new drug) to observe its effects on a dependent variable (the participants' health outcomes). This method allows for establishing cause-and-effect relationships between variables, which is a key characteristic of experimental research design. Choices A, B, and C do not represent experiments. Choice A involves observational analysis of math grades, choice B involves observational analysis of health trends, and choice C involves a survey, none of which involve manipulating variables to establish cause-and-effect relationships.

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