Nursing Elites

1. What is a rod-shaped structure that forms when a single DNA molecule and its associated proteins coil tightly before cell division?

• A. Centromere
• B. Chromatid
• C. Chromosome
• D. Gene

Correct answer: C

Rationale: A chromosome is a rod-shaped structure that forms when a single DNA molecule and its associated proteins coil tightly before cell division. It contains the genetic material and is essential for cell division and replication. The centromere is a specific region of a chromosome that plays a role in cell division. A chromatid is one half of a duplicated chromosome, and a gene is a unit of heredity responsible for specific traits. Therefore, the correct answer is 'Chromosome' as it represents the entire condensed DNA molecule during cell division.

2. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

3. Which of the following organs is responsible for filtering waste from the blood?

• A. Liver
• B. Kidneys
• C. Pancreas
• D. Heart

Correct answer: B

Rationale: The correct answer is B: Kidneys. The kidneys play a vital role in filtering waste from the blood, regulating fluid and electrolyte balance in the body. The liver is involved in detoxification and metabolism, while the pancreas aids in digestion and blood sugar regulation. The heart is responsible for pumping blood throughout the body and does not directly filter waste from the blood.

4. Which type of tissue connects muscles to bones?

• A. Ligaments
• B. Tendons
• C. Cartilage
• D. Muscles

Correct answer: B

Rationale: The correct answer is B: Tendons. Tendons connect muscles to bones, not bones to muscles. They play a crucial role in transmitting the force generated by muscles to move bones, enabling movement. Ligaments (choice A) connect bones to bones, providing stability to joints. Cartilage (choice C) is a connective tissue found in joints, providing cushioning and flexibility. Muscles (choice D) are responsible for generating force through contraction but do not directly connect muscles to bones.

5. What is the primary function of nervous tissue?

• A. Movement
• B. Protection
• C. Communication and coordination
• D. Nutrient transport

Correct answer: C

Rationale: The primary function of nervous tissue is communication and coordination within the body. Nervous tissue is composed of neurons that transmit electrical signals and supporting cells known as neuroglia. Movement is primarily controlled by the muscular system, protection is mainly provided by the skeletal system and immune system, and nutrient transport is carried out by the circulatory system. Therefore, choices A, B, and D are incorrect as they do not align with the primary function of nervous tissue.

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