Nursing Elites

1. Which of the following enzymes unwinds the double-stranded DNA during replication?

• A. Helicase
• B. Ligase
• C. Nuclease
• D. Polymerase

Correct answer: A

Rationale: Helicase is the enzyme responsible for unwinding the double-stranded DNA during replication by breaking the hydrogen bonds between the base pairs. This process creates the replication fork where DNA polymerase can then synthesize new DNA strands. Ligase functions to join Okazaki fragments on the lagging strand, not unwind DNA. Nuclease is involved in DNA repair by removing damaged DNA segments. Polymerase is responsible for synthesizing new DNA strands based on the existing template strands, not for unwinding the DNA.

2. Which term describes the ability of a substance to conduct electricity?

• A. Reactivity
• B. Density
• C. Conductivity
• D. Viscosity

Correct answer: C

Rationale: Conductivity is the correct term used to describe the ability of a substance to conduct electricity. Reactivity is the measure of a substance's tendency to undergo chemical reactions. Density refers to the mass per unit volume of a substance, while viscosity is a measure of a fluid's resistance to flow. In the context of conducting electricity, conductivity is the most appropriate term as it directly relates to the substance's electrical conductive properties.

3. What is the definition of work in physics?

• A. Force applied to an object at rest
• B. Force exerted by an object in motion
• C. Transfer of energy through motion along a direction
• D. Measure of an object's potential energy

Correct answer: C

Rationale: In physics, work is defined as the transfer of energy through motion along a direction. When a force is applied to an object, and the object moves in the direction of the force, work is done on the object. The work done is calculated as the force applied multiplied by the distance the object moves in the direction of the force. Choices A and B do not fully capture the essence of work, as work is about energy transfer through motion, not merely applying force to objects at rest or in motion. Choice D is incorrect as work is not a measure of an object's potential energy; rather, it is the transfer of energy through motion.

4. Parkinson's disease is a neurodegenerative disorder affecting which neurotransmitter?

• A. Dopamine
• B. Acetylcholine
• C. Serotonin
• D. Glutamate

Correct answer: A

Rationale: Parkinson's disease is primarily caused by the loss of dopamine-producing neurons in the brain. Dopamine is a neurotransmitter that plays a crucial role in coordinating movement. The reduction of dopamine levels leads to the characteristic motor symptoms of Parkinson's disease, such as tremors, rigidity, and bradykinesia. Choice B, acetylcholine, is involved in functions like muscle contraction and autonomic nervous system regulation but is not primarily affected in Parkinson's disease. Serotonin (Choice C) is involved in mood regulation and sleep, not the main neurotransmitter affected in Parkinson's disease. Glutamate (Choice D) is the major excitatory neurotransmitter in the central nervous system and is not primarily implicated in Parkinson's disease pathophysiology.

5. What is the largest bone in the human body?

• A. Femur (thigh bone)
• B. Tibia (shin bone)
• C. Humerus (upper arm bone)
• D. Scapula (shoulder blade)

Correct answer: A

Rationale: The femur, also known as the thigh bone, holds the title of the largest bone in the human body. Situated in the upper leg, the femur plays a vital role in supporting the body's weight and enabling movement. While the tibia (shin bone), humerus (upper arm bone), and scapula (shoulder blade) are all essential bones, none of them match the femur in terms of size and importance. The tibia, humerus, and scapula are comparatively smaller bones with specific functions in their respective areas of the body, but they do not surpass the femur in size or significance.

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