HESI A2
HESI A2 Practice Test Anatomy and Physiology
1. Which of the following describes the process of osmosis?
- A. Diffusion of solutes across a membrane
- B. Movement of water across a selectively permeable membrane
- C. Movement of gases across a membrane
- D. Active transport of ions across a membrane
Correct answer: B
Rationale: Osmosis is the process where water molecules move across a selectively permeable membrane from an area of lower solute concentration to an area of higher solute concentration. This movement of water helps to equalize the concentration of solutes on both sides of the membrane. The correct description of osmosis is the movement of water across a selectively permeable membrane, making choice B the right answer. Choices A, C, and D are incorrect because osmosis specifically refers to the movement of water molecules, not solutes, gases, or ions across a membrane.
2. Which hormone is responsible for regulating the sleep-wake cycle?
- A. Melatonin
- B. Thyroxine
- C. Insulin
- D. Cortisol
Correct answer: A
Rationale: Melatonin, produced by the pineal gland, regulates the sleep-wake cycle by responding to light and darkness in the environment. It plays a crucial role in signaling the body when it's time to sleep and wake up, helping to establish and maintain a healthy circadian rhythm. Thyroxine, Insulin, and Cortisol do not directly regulate the sleep-wake cycle, making them incorrect choices for this question.
3. Which of the following is not an example of a nonspecific immune response?
- A. Inflammation
- B. Vasodilation
- C. Release of histamine
- D. Production of antibodies
Correct answer: D
Rationale: The correct answer is D, 'Production of antibodies.' Antibodies are generated as part of the specific immune response, which targets specific antigens. Nonspecific immune responses, such as inflammation, vasodilation, and histamine release, are general defense mechanisms aimed at combating various pathogens. Inflammation is a localized response to infection or injury, vasodilation increases blood flow to the affected area, and histamine release triggers inflammatory responses. It's vital to differentiate between nonspecific responses that provide immediate, general protection and specific responses designed to tackle particular threats.
4. What is the normal pH of human arterial blood?
- A. 6.8
- B. 7.4
- C. 7.9
- D. 8.2
Correct answer: B
Rationale: The normal pH of human arterial blood is approximately 7.4. This slightly alkaline pH is crucial for the proper functioning of enzymes and biochemical processes in the body. Any significant deviation from this pH level can result in serious health issues such as acidosis or alkalosis. Choice A (6.8) is incorrect as it is lower than the normal pH of arterial blood, indicating acidity. Choice C (7.9) and Choice D (8.2) are incorrect as they are higher than the normal pH of arterial blood, indicating alkalinity.
5. Which structure of the respiratory system is involved in gas exchange?
- A. Trachea
- B. Bronchioles
- C. Alveoli
- D. Larynx
Correct answer: C
Rationale: The alveoli are the primary site for gas exchange in the respiratory system. These tiny air sacs in the lungs are where oxygen is taken up into the bloodstream and carbon dioxide is released from the bloodstream into the lungs to be exhaled. The trachea (Choice A) is the windpipe that carries air to and from the lungs but is not directly involved in gas exchange. Bronchioles (Choice B) are smaller airway branches that lead to the alveoli but do not participate in gas exchange themselves. The larynx (Choice D) plays a role in producing sound and protecting the airway but is not primarily responsible for gas exchange.
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