Nursing Elites

1. Which of the following correctly describes mitosis?

• A. Mitosis occurs in germ cells.
• B. Mitosis occurs in somatic cells.
• C. Mitosis involves the reduction of chromosome number by half.
• D. Mitosis produces four genetically different cells.

Correct answer: B

Rationale: The correct answer is B. Mitosis occurs in somatic cells where a single cell divides to produce two identical daughter cells. Germ cells undergo meiosis, not mitosis. Choice C is incorrect as mitosis results in the preservation of the same chromosome number in daughter cells. Choice D is inaccurate as mitosis produces genetically identical cells, not genetically different ones.

2. What is the name of the muscular ring that controls the passage of food from the esophagus to the stomach?

• A. Pyloric sphincter
• B. Cardiac sphincter
• C. Ileocecal valve
• D. Sphincter of Oddi

Correct answer: B

Rationale: The correct answer is the Cardiac sphincter (lower esophageal sphincter). It is situated at the junction of the esophagus and the stomach, controlling the passage of food into the stomach. The cardiac sphincter opens and closes to regulate the flow of food and prevent reflux. The pyloric sphincter, on the other hand, is located between the stomach and the small intestine, not the esophagus and stomach. The ileocecal valve is positioned between the small and large intestines, while the Sphincter of Oddi is found in the duodenum, not between the esophagus and stomach.

3. What is the significance of studying pedigrees in human genetics?

• A. Predicting the exact outcome of genetic crosses in humans.
• B. Tracing the inheritance of complex traits with multiple contributing genes.
• C. Identifying carriers of dominant genetic disorders.
• D. Determining the risk of acquiring a specific mutation de novo.

Correct answer: B

Rationale: Pedigrees are diagrams that show the relationships within a family and can be used to track the inheritance patterns of specific traits or diseases. While pedigrees can provide information on the inheritance of single gene disorders (such as identifying carriers of dominant genetic disorders, as mentioned in option C), their primary significance lies in studying complex traits with multiple contributing genes. These traits do not follow simple Mendelian inheritance patterns and are influenced by both genetic and environmental factors. By analyzing pedigrees, researchers can identify patterns of inheritance for complex traits, such as polygenic diseases or traits influenced by gene-environment interactions. Therefore, option B is the most appropriate choice as it captures the main significance of studying pedigrees in human genetics.

4. Which three parts make up the large intestine?

• A. Duodenum, ileum, jejunum
• B. Cecum, colon, rectum
• C. Ileum, jejunum, rectum
• D. Colon, cecum, ileum

Correct answer: B

Rationale: The correct answer is B: Cecum, colon, rectum. The large intestine is composed of the cecum, colon, and rectum. These parts are responsible for water absorption and feces formation. Choices A, C, and D are incorrect. A contains parts of the small intestine (duodenum, ileum, jejunum), C has a mix of small and large intestine parts, and D includes the small intestine part ileum. Understanding the correct anatomy of the large intestine is essential for distinguishing it from the small intestine.

5. What is the 'lock-and-key' model?

• A. Protein folding
• B. Enzyme-substrate interaction
• C. Muscle contraction
• D. Blood clotting

Correct answer: B

Rationale: The 'lock-and-key' model describes the specificity of the interaction between enzymes and their substrates. In this model, the enzyme's active site acts like a lock that can only be opened by the specific substrate molecule, which serves as the key. This specific binding ensures that enzymes catalyze particular reactions and do not interact with other molecules indiscriminately. Protein folding (option A) is the process by which a protein attains its functional three-dimensional structure but is not directly related to the lock-and-key model. Muscle contraction (option C) and blood clotting (option D) are complex biological processes but are not directly associated with the lock-and-key model of enzyme-substrate interaction.

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