Nursing Elites

1. Which blood component is chiefly responsible for clotting?

• A. Platelets
• B. Red blood cells
• C. Antigens
• D. Plasma cells

Correct answer: A

Rationale: The correct answer is A: Platelets. Platelets are small cell fragments in the blood that play a crucial role in clotting. When there is an injury, platelets adhere to the site and release chemicals that help form a clot to prevent excessive bleeding. Red blood cells transport oxygen, antigens are substances that trigger an immune response, and plasma cells are a type of white blood cell involved in producing antibodies, none of which are primarily responsible for clotting.

2. What is the initial step of the scientific method?

• A. construct a hypothesis
• B. make observations
• C. analyze data
• D. form a question

Correct answer: B

Rationale: The first step of the scientific method is to make observations. This involves collecting data and information about a specific phenomenon or problem. Observations serve as the basis for developing a question to be explored further. Forming a hypothesis (Choice A) comes after making observations, as the hypothesis is an educated guess to explain the observations. Analyzing data (Choice C) occurs later in the scientific method after data has been collected and experiments conducted. Forming a question (Choice D) is a crucial step but typically follows observations in the scientific process.

3. What protein complex controls the progression of mitosis through its activation and degradation?

• A. Ribosome
• B. Cyclin-dependent kinase (CDK)
• C. Centriole
• D. Microtubule

Correct answer: B

Rationale: A) Ribosome: Ribosomes are cellular organelles responsible for protein synthesis and are not directly involved in controlling the progression of mitosis. B) Cyclin-dependent kinase (CDK): CDKs are a family of protein kinases that regulate the cell cycle, including the progression of mitosis. CDK activity is controlled by cyclins, which bind to CDKs to activate them at specific points in the cell cycle. The activation and degradation of cyclins regulate the activity of CDKs, which in turn control the progression of mitosis. C) Centriole: Centrioles are involved in organizing the microtubules of the mitotic spindle but do not directly control the progression of mitosis. D) Microtubule: Microtubules are structural components of the cytoskeleton and are involved in various cellular processes, including mitosis, but they do not control

4. Which of the following cations is found at the center of a heme?

• A. Cr (III)
• B. Cu (II)
• C. Iron (II)
• D. Iron (III)

Correct answer: C

Rationale: The correct answer is Iron (II) (Fe2+), which is the cation found at the center of a heme group. Heme contains an iron (II) ion that is coordinated within the porphyrin ring structure. This iron ion is crucial for the function of heme in binding and transporting oxygen in hemoglobin and myoglobin. Choice A (Cr (III)) is incorrect as chromium is not typically found at the center of a heme group. Choice B (Cu (II)) is incorrect as copper is not the cation typically present in heme. Choice D (Iron (III)) is also incorrect as heme predominantly contains iron (II) at its center, not iron (III).

5. What checkpoint mechanism ensures all chromosomes are attached to the spindle fibers before anaphase begins?

• A. Prometaphase
• B. Metaphase
• C. Cyclin degradation
• D. Sister chromatid cohesion

Correct answer: A

Rationale: A) Prometaphase is the correct answer because it is the stage of mitosis where all chromosomes are attached to the spindle fibers before anaphase begins. During prometaphase, the nuclear envelope breaks down, allowing the spindle fibers to attach to the kinetochores of the chromosomes. This attachment is necessary for proper chromosome alignment and segregation during anaphase. B) Metaphase is incorrect because it is the stage where chromosomes are aligned at the metaphase plate but do not necessarily have all spindle fibers attached. C) Cyclin degradation is incorrect because it is a regulatory mechanism that controls the progression of the cell cycle but is not specifically related to ensuring all chromosomes are attached to spindle fibers. D) Sister chromatid cohesion is incorrect because it refers to the physical connection between sister chromatids that is maintained until anaphase, but it does not ensure that all chromosomes are attached to spindle fibers.

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