HESI A2
HESI A2 Anatomy and Physiology Practice Exam
1. When are gallstones most problematic?
- A. When they block a duct
- B. When they contain cholesterol
- C. When they contain bilirubin
- D. When they begin to dissolve
Correct answer: A
Rationale: Gallstones become most problematic when they block a duct, such as the bile duct or cystic duct. This blockage can lead to various complications, including inflammation, infection, and even damage to the gallbladder or liver. In severe cases, a blocked duct can cause intense pain, jaundice, and other serious symptoms that require medical intervention. Choices B, C, and D are incorrect because the presence of cholesterol or bilirubin in gallstones or the process of dissolution do not necessarily indicate when gallstones become most problematic. The critical issue arises when the stones obstruct a duct, leading to complications.
2. Which structure in the kidney filters blood to form urine?
- A. Nephron
- B. Glomerulus
- C. Bowman's capsule
- D. Loop of Henle
Correct answer: B
Rationale: The glomerulus is a key structure in the kidney responsible for filtering blood. It consists of a network of capillaries that filter waste products and excess substances from the blood, allowing the formation of urine. While the nephron, Bowman's capsule, and Loop of Henle are also essential components of the kidney's filtration system, the glomerulus is specifically involved in the initial blood filtration process. The nephron is the functional unit of the kidney, Bowman's capsule surrounds the glomerulus and collects the filtrate, and the Loop of Henle is responsible for reabsorption and concentration of urine, not the initial blood filtration.
3. Which organ is responsible for the production of insulin?
- A. Thyroid gland
- B. Pituitary gland
- C. Pancreas
- D. Adrenal gland
Correct answer: C
Rationale: The correct answer is C: Pancreas. The pancreas is responsible for producing insulin, a hormone that regulates blood glucose levels by facilitating the uptake of glucose into cells. Insulin is crucial for maintaining proper blood sugar levels and is produced by specialized cells within the pancreas known as beta cells. Choices A, B, and D are incorrect because the thyroid gland, pituitary gland, and adrenal gland do not produce insulin. The thyroid gland produces hormones that regulate metabolism, the pituitary gland releases various hormones that control other glands, and the adrenal gland produces hormones like cortisol and adrenaline.
4. Which hormone is secreted by the pancreas to lower blood glucose levels?
- A. Insulin
- B. Glucagon
- C. Somatostatin
- D. Cortisol
Correct answer: A
Rationale: Insulin is secreted by the pancreas to lower blood glucose levels by facilitating the uptake of glucose into cells. It promotes the storage of glucose as glycogen in the liver and muscles, reducing blood sugar levels. Glucagon, on the other hand, works to raise blood glucose levels by stimulating the breakdown of glycogen into glucose and releasing it into the bloodstream. Somatostatin regulates the endocrine system and inhibits the release of insulin and glucagon. Cortisol is a hormone produced by the adrenal glands, not the pancreas, and it plays a role in stress response and metabolism, but it does not directly lower blood glucose levels.
5. Which vitamin is essential for the synthesis of collagen?
- A. Vitamin C
- B. Vitamin D
- C. Vitamin B12
- D. Vitamin K
Correct answer: A
Rationale: The correct answer is Vitamin C. Vitamin C is essential for the synthesis of collagen, a protein crucial for maintaining the structure and integrity of skin, blood vessels, and bones. It plays a key role in the hydroxylation of proline and lysine residues in collagen synthesis, which is necessary for the stability and strength of collagen fibers. Choice B: Vitamin D is essential for bone health and calcium absorption but is not directly involved in collagen synthesis. Choice C: Vitamin B12 is important for red blood cell formation and neurological function but is not directly related to collagen synthesis. Choice D: Vitamin K is necessary for blood clotting and bone metabolism but does not play a direct role in collagen synthesis.
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