HESI A2
HESI A2 Anatomy and Physiology Practice Exam
1. When are gallstones most problematic?
- A. When they block a duct
- B. When they contain cholesterol
- C. When they contain bilirubin
- D. When they begin to dissolve
Correct answer: A
Rationale: Gallstones become most problematic when they block a duct, such as the bile duct or cystic duct. This blockage can lead to various complications, including inflammation, infection, and even damage to the gallbladder or liver. In severe cases, a blocked duct can cause intense pain, jaundice, and other serious symptoms that require medical intervention. Choices B, C, and D are incorrect because the presence of cholesterol or bilirubin in gallstones or the process of dissolution do not necessarily indicate when gallstones become most problematic. The critical issue arises when the stones obstruct a duct, leading to complications.
2. Which hormone is produced by the pancreas?
- A. Insulin
- B. Glucagon
- C. Somatostatin
- D. Cortisol
Correct answer: A
Rationale: Insulin is the correct answer. Insulin is produced by the pancreas and plays a crucial role in regulating blood glucose levels. It facilitates the uptake of glucose into cells, helping to lower blood sugar levels. Glucagon, on the other hand, is also produced by the pancreas but functions to raise blood glucose levels by stimulating the release of glucose from the liver. Somatostatin is another hormone produced by the pancreas that helps regulate the endocrine system. Cortisol, produced by the adrenal glands, plays a role in stress response and metabolism, not by the pancreas.
3. Which gland produces melatonin?
- A. Pineal gland
- B. Thyroid gland
- C. Adrenal gland
- D. Pituitary gland
Correct answer: A
Rationale: The correct answer is the Pineal gland. This gland is responsible for producing melatonin, a hormone that helps regulate the sleep-wake cycle. Melatonin production is influenced by exposure to light, with levels typically rising in the evening to promote sleep and falling in the morning to aid wakefulness. The Thyroid gland (choice B) produces hormones that regulate metabolism, the Adrenal gland (choice C) produces hormones like adrenaline and cortisol, and the Pituitary gland (choice D) controls several other glands in the endocrine system.
4. Where do nearly all of the gaseous exchanges between air and blood take place in the lungs?
- A. Pleura
- B. Trachea
- C. Bronchioles
- D. Alveoli
Correct answer: D
Rationale: Nearly all gaseous exchanges between air and blood take place in the alveoli of the lungs. The walls of the alveoli are thin and surrounded by an extensive network of tiny blood vessels called capillaries. Oxygen from the air diffuses through the alveoli walls and into the bloodstream, while carbon dioxide, a waste product, diffuses from the blood into the alveoli to be exhaled out of the body. This process is essential for respiration and providing oxygen to the body's cells. Choices A, B, and C are incorrect. Pleura is the membrane surrounding the lungs, trachea is the windpipe that carries air to the lungs, and bronchioles are the smaller air passages in the lungs. However, the primary site for gaseous exchange is the alveoli due to their structure and function.
5. Which cellular structure is responsible for producing energy?
- A. Nucleus
- B. Mitochondria
- C. Ribosome
- D. Golgi apparatus
Correct answer: B
Rationale: Mitochondria are the organelles responsible for producing energy in the cell through a process called cellular respiration. They are often referred to as the powerhouses of the cell due to their role in generating ATP, the cell's energy currency. The nucleus is not involved in energy production but houses the cell's genetic material. Ribosomes are responsible for protein synthesis, not energy production. The Golgi apparatus is involved in processing and packaging proteins for secretion, not energy production.
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