Nursing Elites

1. What type of genetic testing can reveal an individual's susceptibility to certain diseases?

• A. Karyotyping
• B. Pharmacogenomics
• C. Paternity testing
• D. Microarray analysis

Correct answer: D

Rationale: A) Karyotyping is a genetic test that examines an individual's chromosomes to detect abnormalities such as extra or missing chromosomes. It is not typically used to reveal an individual's susceptibility to certain diseases. B) Pharmacogenomics is the study of how genes affect a person's response to drugs. It focuses on how genetic variations can influence drug response, rather than susceptibility to diseases. C) Paternity testing is a genetic test used to determine the biological relationship between a child and an alleged father. It is not used to reveal an individual's susceptibility to diseases. D) Microarray analysis is a type of genetic testing that can reveal an individual's susceptibility to certain diseases by analyzing variations in their DNA. It can identify genetic markers associated with increased risk for specific conditions, allowing for personalized risk assessment and preventive measures.

2. Which organ in the body is responsible for filtering toxins from the blood?

• A. Kidneys
• B. Liver
• C. Heart
• D. Lungs

Correct answer: B

Rationale: The liver is the organ responsible for filtering toxins from the blood. It plays a crucial role in detoxification by processing and eliminating harmful substances from the body. The kidneys primarily filter waste and excess substances from the blood to form urine, while the heart pumps blood throughout the body and the lungs facilitate gas exchange by oxygenating blood. Therefore, the correct answer is the liver as it is specifically involved in detoxifying the blood.

3. What is the role of the spindle apparatus in cell division?

• A. To separate sister chromatids
• B. To move chromosomes to opposite poles of the cell
• C. To form a new nuclear envelope around each daughter cell
• D. To synthesize new DNA

Correct answer: B

Rationale: The spindle apparatus, composed of microtubules, plays a crucial role in cell division (mitosis and meiosis) by ensuring proper chromosome separation and distribution to opposite poles of the cell. This segregation is vital for creating two genetically identical daughter cells in mitosis or four haploid daughter cells in meiosis. Choice A is incorrect because the separation of sister chromatids is specifically carried out by kinetochore fibers within the spindle apparatus. Choice C is inaccurate as the formation of a new nuclear envelope occurs post chromosome segregation. Choice D is incorrect as DNA synthesis does not occur within the spindle apparatus; it takes place during the S phase of the cell cycle.

4. What enzymes do lysosomes contain, leading to their nickname as the cell's 'suicide bags'?

• A. Hydrolytic enzymes
• B. Ligases (bonding enzymes)
• C. Transferases (molecule transfer)
• D. Oxidoreductases (redox reactions)

Correct answer: A

Rationale: Lysosomes are organelles filled with hydrolytic enzymes that break down proteins, nucleic acids, lipids, and carbohydrates. These enzymes aid in digesting cellular waste and foreign substances, hence the term 'suicide bags' due to their involvement in cell degradation and recycling. Ligases are enzymes that catalyze the joining of two large molecules by forming a new chemical bond, not present in lysosomes. Transferases are enzymes that catalyze the transfer of functional groups from one molecule to another, not found in lysosomes. Oxidoreductases are enzymes involved in oxidation-reduction reactions, which are not the primary function of lysosomes.

5. Which of the following nucleobases does not exist in RNA?

• A. Uracil
• B. Thymine
• C. Cytosine
• D. Guanine

Correct answer: B

Rationale: The correct answer is 'B: Thymine'. Thymine is a nucleobase found in DNA but is replaced by uracil in RNA. RNA contains Uracil, Cytosine, and Guanine as its nucleobases. Cytosine and Guanine are present in both DNA and RNA, while Thymine is exclusive to DNA and Uracil is specific to RNA.

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