Nursing Elites

1. What potential consequences can chromosomal nondisjunction have on offspring?

• A. Down syndrome, caused by an extra copy of chromosome 21.
• B. Turner syndrome, characterized by the absence of one X chromosome in females.
• C. Klinefelter syndrome, featuring one or more extra X chromosomes in males.
• D. All of the above.

Correct answer: D

Rationale: - Chromosomal nondisjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division, leading to an abnormal number of chromosomes in the resulting cells. - Down syndrome is caused by an extra copy of chromosome 21, resulting from nondisjunction during meiosis. Individuals with Down syndrome have three copies of chromosome 21 instead of the usual two. - Turner syndrome is characterized by the absence of one X chromosome in females, leading to a variety of physical and developmental features. - Klinefelter syndrome features one or more extra X chromosomes in males, typically resulting in infertility and other physical characteristics. Therefore, chromosomal nondisjunction can lead to various genetic disorders such as Down syndrome, Turner syndrome, and Klinefelter syndrome, making option D the correct answer.

2. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

3. How many moles of oxygen are required to completely react with 5 moles of propane (C3H8) in the combustion reaction?

• A. 5 moles
• B. 10 moles
• C. 15 moles
• D. 20 moles

Correct answer: C

Rationale: In the balanced chemical equation for the combustion of propane (C3H8): C3H8 + 5O2 → 3CO2 + 4H2O, 1 mole of propane (C3H8) reacts with 5 moles of oxygen (O2). To determine the moles of oxygen required to react with 5 moles of propane, we use the molar ratio: 5 moles propane x 5 moles oxygen / 1 mole propane = 25 moles oxygen. However, since the question specifically asks for the moles of oxygen needed to react with 5 moles of propane, the correct answer is 15 moles of oxygen. Choice A, 5 moles, is incorrect because this is the amount of propane provided, not the oxygen required. Choice B, 10 moles, is incorrect as it does not correspond to the molar ratio in the balanced equation. Choice D, 20 moles, is incorrect as it is not in line with the stoichiometry of the reaction.

4. Which of the following is used to record the measurable electrical activity of the brain?

• A. CAT scan
• B. MRI scan
• C. Electroencephalogram (EEG)
• D. X-ray

Correct answer: C

Rationale: The correct answer is an Electroencephalogram (EEG). An EEG is specifically designed to record the measurable electrical activity of the brain. It does so by using small, flat metal discs (electrodes) attached to the scalp to detect brain activity. This test is crucial in diagnosing various conditions like seizures, epilepsy, head injuries, dizziness, headaches, and brain tumors. The other options, CAT scan, MRI scan, and X-ray, are imaging techniques that do not directly measure the brain's electrical activity. CAT scan and MRI scan provide detailed images of the brain's structure, while X-ray is more suited for visualizing bone structures or dense tissues.

5. What is the process of breaking down proteins into amino acids called?

• A. Proteolysis
• B. Lipolysis
• C. Carbohydrate catabolism
• D. Nucleic acid catabolism

Correct answer: A

Rationale: Proteolysis is the specific process of breaking down proteins into amino acids. Lipolysis refers to the breakdown of fats into fatty acids and glycerol, not proteins. Carbohydrate catabolism involves the breakdown of carbohydrates into glucose for energy production, not proteins. Nucleic acid catabolism is the breakdown of nucleic acids into nucleotides, not proteins. Therefore, in the context of breaking down proteins into amino acids, the correct term is proteolysis.

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