Nursing Elites

1. What is the main target organ for insulin, the hormone produced by the pancreas?

• A. Liver
• B. Kidneys
• C. Muscles
• D. Brain

Correct answer: C

Rationale: The main target organ for insulin is muscles. Insulin plays a crucial role in regulating glucose metabolism by promoting the uptake of glucose into muscle cells. This glucose can then be utilized for energy production or stored for later use. Therefore, muscles are the primary site where insulin exerts its effects on glucose uptake and utilization. The liver primarily responds to insulin by regulating glucose storage and release, but the main target for insulin-mediated glucose uptake is muscles. Kidneys are not a target organ for insulin action in glucose metabolism. The brain does not heavily rely on insulin for glucose uptake as it primarily uses glucose independently of insulin for energy production.

2. What is the role of the spindle apparatus in cell division?

• A. To separate sister chromatids
• B. To move chromosomes to opposite poles of the cell
• C. To form a new nuclear envelope around each daughter cell
• D. To synthesize new DNA

Correct answer: B

Rationale: The spindle apparatus, composed of microtubules, plays a crucial role in cell division (mitosis and meiosis) by ensuring proper chromosome separation and distribution to opposite poles of the cell. This segregation is vital for creating two genetically identical daughter cells in mitosis or four haploid daughter cells in meiosis. Choice A is incorrect because the separation of sister chromatids is specifically carried out by kinetochore fibers within the spindle apparatus. Choice C is inaccurate as the formation of a new nuclear envelope occurs post chromosome segregation. Choice D is incorrect as DNA synthesis does not occur within the spindle apparatus; it takes place during the S phase of the cell cycle.

3. How do efferent fibers exit the spinal cord?

• A. Through the anterior aspect
• B. Through the dorsal aspect
• C. Through the ventral aspect
• D. Through the lateral aspect

Correct answer: C

Rationale: Efferent fibers, which carry motor commands, exit the spinal cord through the ventral aspect, also known as the anterior aspect. The correct answer is C, 'Through the ventral aspect.' Efferent fibers exiting through the ventral aspect are responsible for carrying motor commands from the spinal cord to the muscles and glands. Choices A, B, and D are incorrect. Efferent fibers do not exit through the dorsal, lateral, or anterior aspects of the spinal cord.

4. Which type of mutation involves a change in the number of chromosomes?

• A. Point mutation
• B. Frameshift mutation
• C. Missense mutation
• D. Aneuploidy

Correct answer: D

Rationale: A) Point mutation involves a change in a single nucleotide base pair within the DNA sequence. B) Frameshift mutation involves the insertion or deletion of nucleotides, causing a shift in the reading frame of the genetic code. C) Missense mutation involves a single nucleotide change that results in a codon that codes for a different amino acid. D) Aneuploidy involves a change in the number of chromosomes, where an individual may have an extra chromosome (trisomy) or a missing chromosome (monosomy). Aneuploidy can lead to genetic disorders such as Down syndrome (trisomy 21) or Turner syndrome (monosomy X). Changing the number of chromosomes is a characteristic feature of aneuploidy, making it the correct answer. Point mutation, frameshift mutation, and missense mutation do not involve a change in the number of chromosomes and are focused on alterations at the nucleotide level within the DNA sequence.

5. What is the difference between the atomic number and the mass number of an atom?

• A. The atomic number is the number of protons in the nucleus, while the mass number is the total number of protons and neutrons in the nucleus.
• B. The atomic number is the number of electrons in an atom, while the mass number is the total number of protons and neutrons in the nucleus.
• C. The atomic number is the number of neutrons in the nucleus, while the mass number is the total number of protons and electrons in an atom.
• D. The atomic number is the number of protons and neutrons in the nucleus, while the mass number is the total number of electrons in an atom.

Correct answer: A

Rationale: The atomic number of an atom represents the number of protons in its nucleus, which defines the element's identity. On the other hand, the mass number corresponds to the total sum of protons and neutrons in the nucleus. Therefore, the key distinction between the atomic number and the mass number lies in the fact that the atomic number specifically counts the protons, whereas the mass number encompasses both protons and neutrons. Choice B is incorrect because the atomic number is not related to the number of electrons but rather to the number of protons. Choice C is incorrect because the atomic number is not the number of neutrons but the number of protons. Choice D is incorrect because the atomic number does not include neutrons; it is solely the number of protons.

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